Neuroimage
October 1, 2019
Jessica Samogin, Quanying Liu, Marco Marino et al.
Electrophysiological studies revealed that different neuronal oscillations, among which the alpha (8-13 Hz) rhythm in particular, but also the beta (13-30 Hz) and gamma (30-80 Hz) rhythms, are modulated during rest in the default mode network (DMN). Little is known, however, about the role of these rhythms in supporting DMN connectivity. Biophysical studies suggest that lower and higher...
Brain Imaging and Behavior
October 1, 2019
Inessa Kraft, Joana Bisol Balardin, João Ricardo Sato et al.
Quality of life is an important issue concerning people all over the world and affecting patients in the mental health field. When considering the potential neural links between quality of life and the brain, a brain network that comes into mind is the default mode network (DMN). Its architecture and function has been investigated in relation to various research fields including social and...
Secrets of Creativity
September 30, 2019
Marcus E. Raichle
Abstract: It may be surprising to learn that the brain’s intrinsic, ongoing activity is the dominant mode of brain function, present and largely nonconscious whether we are daydreaming, sleeping, or engaged in the full range of human behaviors. Intrinsic activity is easily seen in the ongoing electrical activity of the brain, where extensive averaging is needed to separate evoked activity from...
medRxiv
September 29, 2019
Lorenzo Pasquini, Fernanda Palhano-Fontes, Draulio B Araujo
24 citations
preprint
Abstract Background Neuroimaging studies have just begun to explore the acute effects of psychedelics on large-scale brain networks’ functional organization. Even less is known on the neural correlates of subacute effects taking place days after the psychedelic experience. This study explores the subacute changes of primary sensory brain networks and networks supporting higher-order affective...
Frontiers in Neurology
September 18, 2019
Yang Wang, Yun Qin, Hui Li et al.
Internet addiction (IA) has become a global mental and social problem, which may lead to a series of psychiatric symptoms including uncontrolled use of internet, and lack of concentration. However, the exact pathophysiology of IA remains unclear. Most of functional connectivity studies were based on pre-selected regions of interest (ROI), which could not provide a comprehensive picture of the...
Human Brain Mapping
September 18, 2019
Norman Zacharias, Francesco Musso, Felix Müller et al.
70 citations
In resting-state functional connectivity experiments, a steady state (of consciousness) is commonly supposed. However, recent research has shown that the resting state is a rather dynamic than a steady state. In particular, changes of vigilance appear to play a prominent role. Accordingly, it is critical to assess the state of vigilance when conducting pharmacodynamic studies with resting-state...
Trends in Cognitive Sciences
August 16, 2019
A. Satpute, Kristen A. Lindquist
Emotions are often assumed to manifest in subcortical limbic and brainstem structures. While these areas are clearly important for representing affect (e.g. valence, arousal), we propose that the default mode network (DMN) is additionally important for constructing discrete emotional experiences (of anger, fear, disgust, etc.). Findings from neuroimaging studies, invasive electrical stimulation...
Neuroimage
August 1, 2019
Lukasz Smigielski, Milan Scheidegger, Michael Kometer et al.
261 citations
Both psychedelics and meditation exert profound modulatory effects on consciousness, perception and cognition, but their combined, possibly synergistic effects on neurobiology are unknown. Accordingly, we conducted a randomized, double-blind, placebo-controlled study with 38 participants following a single administration of the psychedelic psilocybin (315 μg/kg p.o.) during a 5-day mindfulness...
Frontiers in Aging Neuroscience
July 2, 2019
Danilo Forghieri Santaella, Joana Bisol Balardin, Rui F. Afonso et al.
37 citations
Large-scale brain networks exhibit changes in functional connectivity during the aging process. Recent literature data suggests that Yoga and other contemplative practices may revert, at least in part, some of the aging effects in brain functional connectivity, including of the Default Mode Network (DMN). The aim of this cross-sectional investigation was to compare resting-state functional...
Nature Communications
June 4, 2019
T. Pascoal, S. Mathotaarachchi, M. Kang et al.
The link between brain amyloid-β (Aβ), metabolism, and dementia symptoms remains a pressing question in Alzheimer’s disease. Here, using positron emission tomography ([18F]florbetapir tracer for Aβ and [18F]FDG tracer for glucose metabolism) with a novel analytical framework, we found that Aβ aggregation within the brain’s default mode network leads to regional hypometabolism in distant but...