bioRxiv
February 12, 2021
S. Trova, Yukie Tsuji, Haruka Horiuchi et al.
preprint
Experienced meditators reduce the activity of the default mode network (DMN), a brain system preferentially active when people are not engaged in specific tasks. However, the neural modulation of the DMN in novices remain largely unexplored. By using electroencephalography, we investigated the DMN functional connectivity in two groups of novices: the meditation group practiced six consecutive...
Brain Connectivity
February 1, 2021
Danish M. Khan, Nidal Kamel, Mustapha Muzaimi et al.
Introduction: With the recent technical advances in brain imaging modalities such as magnetic resonance imaging, positron emission tomography, and functional magnetic resonance imaging ( f MRI), researchers' interests have inclined over the years to study brain functions through the analysis of the variations in the statistical dependence among various brain regions. Through its wide use in...
Developmental Cognitive Neuroscience
January 27, 2021
M. DeSerisy, Bruce Ramphal, D. Pagliaccio et al.
Background Anticorrelated resting state connectivity between task-positive and task-negative networks in adults supports flexible shifting between externally focused attention and internal thought. Findings suggest that children show positive correlations between task-positive (frontoparietal; FP) and task-negative (default mode; DMN) networks. FP-DMN connectivity also associates with...
Nature Reviews Neuroscience
January 22, 2021
Yaara Yeshurun, Mai Nguyen, Uri Hasson
701 citations
The default mode network (DMN) is classically considered an 'intrinsic' system, specializing in internally oriented cognitive processes such as daydreaming, reminiscing and future planning. In this Perspective, we suggest that the DMN is an active and dynamic 'sense-making' network that integrates incoming extrinsic information with prior intrinsic information to form rich, context-dependent...
Brain Communications
2021
AbstractCortical accumulation of amyloid beta is one of the first events of Alzheimer’s disease pathophysiology, and has been suggested to follow a consistent spatiotemporal ordering, starting in the posterior cingulate cortex, precuneus and medio-orbitofrontal cortex. These regions overlap with those of the default mode network, a brain network also involved in memory functions. Aberrant...
Pharmacology, Biochemistry, and Behavior
December 29, 2020
Sara de la Salle, Joëlle Choueiry, D. Shah et al.
N-methyl-D-aspartate receptor (NMDAR) antagonists administered to healthy humans results in schizophrenia-like symptoms, which are thought in part to be related to glutamatergically altered electrophysiological connectivity in large-scale intrinsic functional brain networks. Here, we examine resting-state source electroencephalographic (EEG) connectivity within and between the default mode...
Brain and Behavior
December 18, 2020
Zainab Sandhu, Onur Tanglay, I. Young et al.
The default mode network (DMN) is an important mediator of passive states of mind. Multiple cortical areas, such as the anterior cingulate cortex, posterior cingulate cortex, and lateral parietal lobe, have been linked in this processing, though knowledge of network connectivity had limited tractographic specificity.
Neuron
December 1, 2020
Jennifer D. Whitesell, Adam Liska, Ludovico Coletta et al.
Summary The evolutionarily conserved default mode network (DMN) is a distributed set of brain regions coactivated during resting states that is vulnerable to brain disorders. How disease affects the DMN is unknown, but detailed anatomical descriptions could provide clues. Mice offer an opportunity to investigate structural connectivity of the DMN across spatial scales with cell-type resolution....
medRxiv Preprint Server
November 26, 2020
Giulia Bommarito, Anjali Tarun, Younes Farouj et al.
7 citations
preprint
Background Modifications in brain function remain relatively unexplored in progressive multiple sclerosis (PMS), despite their potential to provide new insights into the pathophysiology of this disease stage.
Neural Plasticity
November 23, 2020
Yan Cui, Qiao Chen, Yang Xia et al.
The default-mode network (DMN) is believed to be associated with levels of consciousness, but how the functional connectivity (FC) of the DMN changes across different states of consciousness is still unclear. In the current work, we addressed this issue by exploring the coactive micropattern (CAMP) networks of the DMN according to the CAMPs of rat DMN activity during the sleep-wake cycle and...