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Lei Zhang

6 papers in the library · 109 citations · publishing 2011-2026

Papers

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Self-transcendence: Is External Feature Guidance Indispensable for Accelerating Diffusion Transformer Training?

arXiv Preprint Archive January 12, 2026 Lingchen Sun, Rongyuan Wu, Zhengqiang Zhang et al.

Recent works such as REPA have shown that guiding diffusion models with external semantic features (e.g., DINO) can significantly accelerate the training of diffusion transformers (DiTs). However, the use of pretrained external features as guidance signals introduces additional dependencies. We argue that DiTs actually have the power to guide the training of themselves, and propose...

Effects of long-term mindfulness meditation training on attentional capacity in professional male fencer athletes.

Scientific Reports April 15, 2025 Hong Ding, Lei Zhang, Chao Ma et al. 9 citations

Attention is a crucial cognitive ability for sports performance. The current research aimed to investigate whether long-term mindfulness meditation (MM) intervention enhances male athletes' attentional function and alters the activity of brain regions related to attention. In this experiment, we recruited 47 professional male fencer athletes completed two main trials-an MM trial and a control...

A whole genome atlas of 81 Psilocybe genomes as a resource for psilocybin production.

F1000Research September 23, 2021 Kevin Mckernan, Liam T. Kane, Yvonne Helbert et al. 10 citations

The Psilocybe genus is well known for the synthesis of valuable psychoactive compounds such as Psilocybin, Psilocin, Baeocystin and Aeruginascin. The ubiquity of Psilocybin synthesis in Psilocybe has been attributed to a horizontal gene transfer mechanism of a ~20Kb gene cassette. A recently published highly contiguous reference genome derived from long read single molecule sequencing has...

Mindfulness-based therapy versus cognitive behavioral therapy for people with anxiety symptoms: a systematic review and meta-analysis of random controlled trials

Annals of Palliative Medicine July 1, 2021 Jingjing Li, Zhu Cai, Xiaoming Li et al. 58 citations

BACKGROUND: Mindfulness-based interventions (MBIs) and cognitive behavioral therapy (CBT) have both been shown to be effective treatment approaches for anxiety. The purpose of this paper was to directly investigate the ability of MBIs and CBT to improve anxiety symptoms (primary outcome), as well as depression symptoms and sleep quality (second outcome). METHODS: We searched the following...

Mindfulness-based cognitive therapy for bipolar disorder: A systematic review and meta-analysis.

Psychiatry Research May 25, 2020 Rongrong Xuan, Xiaoming Li, Yuxi Qiao et al.

BACKGROUND Mindfulness-based cognitive therapy (MBCT) is an increasingly popular treatment for major depression and anxiety disorder, but has shown inconsistent efficacy for bipolar disorder (BD). Therefore, we conducted a meta-analysis to assess the general efficacy of MBCT for BD. METHODS Ten studies were identified that fulfilled the current inclusion criteria, including three controlled and...

1-[(1-Methyl-1H-imidazol-2-yl)methyl]-4-phenylpiperidines as mGluR2 Positive Allosteric Modulators for the Treatment of Psychosis

Journal of Medicinal Chemistry March 2, 2011 Lei Zhang, Michael A. Brodney, John Candler et al. 32 citations

A novel series of mGluR2 positive allosteric modulators (PAMs), 1-[(1-methyl-1H-imidazol-2-yl)methyl]-4-phenylpiperidines, is herein disclosed. Structure-activity relationship studies led to potent, selective mGluR2 PAMs with excellent pharmacokinetic profiles. A representative lead compound (+)-17e demonstrated dose-dependent inhibition of methamphetamine-induced hyperactivity and...