Journal of addiction psychiatry
August 14, 2026
Sue D. Muggar, Jaime A. Perez, F. Laviolette et al.
Objectives: To utilize a retrospective observational design to characterize adolescents aged 13 - 17 presenting to emergency rooms (ER) in the United States (US) from 2016 to 2024 with psychosis and/or delta-9-tetrahydrocannabinol (THC) exposure via urine drug screens (UDS) and to evaluate trends in THC exposure, psychiatric comorbidities, and demographics. Material and Methods: De-identified,...
PLoS One
August 13, 2026
Paige Copeland, Quinn Malone, Brian H. Dalton et al.
The psychoactive component of cannabis, Δ9-tetrahydrocannabinol (THC), is known to alter cognitive-motor function; however, despite the high prevalence of cannabis use globally, the time course of the effects of ingesting THC is unclear. To allow future studies to accurately time the assessment of the impacts of cannabis on behaviour, this study aimed to establish a detailed time series of...
Psychology of Addictive Behaviors
August 13, 2026
Bridgid M Conn, Alisha Osornio, Kaia Sheean et al.
Despite increased naturalistic psychedelic use in the United States, limited studies explore factors currently contributing to use among ethnically and racially diverse psychedelic and cannabis-using adults. This study employs thematic analysis using qualitative data to explore the factors contributing to contemporary psychedelic use. Qualitative interviews (conducted in 2022-2023) from a...
Psychopharmacology
August 11, 2026
Madison Wright, Justin Matheson, Adam Zaweel et al.
RATIONALE Sex differences in the effects of cannabis have been demonstrated in animals, though the human evidence is more equivocal. In particular, more work is needed to better understand interactions between sex and dose in determining acute pharmacological effects of cannabis, especially at higher potencies of Δ9-tetrahydrocannabinol (THC). OBJECTIVES Sex differences were examined following...
Frontiers in Pharmacology
August 10, 2026
N. Miguel-Ramiro, N. Lamanna-Rama, M. Casquero-Veiga et al.
Background Disruptions in the gut-brain-microbiota axis are increasingly linked to psychiatric disorders. While cannabinoids possess immunomodulatory and neuroprotective properties, their impact on the microbial architecture during critical neurodevelopmental periods remains poorly understood. This exploratory study investigated whether adolescent treatment with delta-9-tetrahydrocannabinol...
Alcoholism & Drug Abuse Weekly
August 10, 2026
Alison Knopf
Cannabis use and cannabis use disorder (CUD) are common in early‐onset psychosis. Clinical presentation is key when determining which is present and which to treat first. But reducing cannabis use would help. A study published in the Journal of the American Academy of Child and Adolescent Psychiatry found that cannabis use preceded the psychosis symptoms. Researchers found that screening and...
Neurochemical Research
August 8, 2026
Duarte R Carvalhinho, Sandra I Marques, Sandra Leal et al.
The endocannabinoid system (ECS) plays a key role in regulating neurogenesis and inflammatory processes in the brain. The increasing prevalence of Cannabis use among women highlights the importance of understanding sex-specific effects of cannabinoids, particularly in the context of hormonal interactions. This study aimed to investigate the effects of delta-9-tetrahydrocannabinol (THC) and...
Otago University Research Archive
August 4, 2026
Caitlin Elaine Thorburn
While cannabis has been reported to have many therapeutic utilisations, minimal studies have explored the use behaviours of individuals with ADHD in New Zealand. Due to the considerably high rates of cannabis use within this population, it is necessary that this gap in the literature is explored. Of the analyses that have been conducted, it appears that the self-medication hypothesis may...
bioRxiv (Cold Spring Harbor Laboratory)
August 4, 2026
Conor H. Murray, Michael Angyus, Sam Suchin et al.
preprint
Abstract Altered states of consciousness (ASC) refer to states that differ markedly from normal waking consciousness. ASC may occur spontaneously, such as in dreaming, or through consciousness modifying techniques, from meditation, to cannabis and psychedelics. The etymology behind the term psychedelic, meaning mind-manifesting, is based on the hypothesis that certain substances, including...
Brain Research Bulletin
August 1, 2026
Barkha J. Yadav-Samudrala, Laith E. Sawaqed, Caitlin J. Huguely Wilkinson et al.
While combined antiretroviral therapy (cART) has transitioned HIV-1 into a manageable chronic condition, it fails to eradicate latent viral reservoirs in the central nervous system (CNS) that drive persistent neuroinflammation and synaptodendritic injury. Consequently, people living with human immunodeficiency virus type-1 (HIV-1) often utilize cannabis to manage neurological symptoms, yet the...