Physiology & Behavior
April 17, 2026
Li Shen Chong, Rachel C. Bucher, Edward Merritt et al.
• Brief mindfulness intervention (bMBI) impacts autonomic nervous system functioning. • bMBI increased RSA and reduced SCL during mindfulness relative to the attention control condition. • bMBI reduced blood pressure after mindfulness and stress relative to controls. • The bMBI group displayed reciprocal RSA and SCL patterns (↑RSA, ↓SCL) during stress. • Controls showed non-reciprocal RSA-SCL...
Physiology & Behavior
September 1, 2025
Yiru Dong, Sebastian Goodwin-Groen, Jessie Ma et al.
4 citations
The activity-based anorexia (ABA) animal model captures key maladaptive behaviors of anorexia nervosa - starvation-evoked hyperactivity, voluntary food restriction, severe weight loss and elevated anxiety-like behavior. By repeating ABA induction, the model reveals an animal's gain of resilience against ABA relapses and concomitant synaptic plasticity. We review findings on the efficacy of...
Physiology & Behavior
May 20, 2025
Kaspar McCoy, Felicia Reed, Kyna‐anne Conn et al.
4 citations
Psilocybin, a serotonergic psychedelic, has emerged as a promising treatment for a range of mental health conditions, including anorexia nervosa. Recent insights from animal models and human imaging studies suggest psilocybin enhances cognitive flexibility and modifies reward processing - two core processes disrupted in anorexia nervosa. Both cognitive flexibility and reward processing are...
Physiology & Behavior
October 1, 2024
Jasmine Shakir, Megan Pedicini, Brianna C Bullock et al.
5 citations
There is growing interest in the therapeutic potential of psilocybin for the treatment of a wide variety of medical problems, and even for the promotion of wellbeing among healthy individuals. Interestingly, among the many proposed indications, both obesity and anorexia nervosa (AN) have been discussed. However, the effect of psilocybin on appetitive behavior and metabolism is not well known....
Physiology & Behavior
March 15, 2015
Hwi-Jin Im, Yoon-Jung Kim, Hyeong-Geug Kim et al.
Kouksundo is a traditional Korean mind-body practice that has been practiced for thousands of years. We investigated the effects of Kouksundo on oxidative stress-related biomarkers and stress hormones. A single-arm observational study was conducted on 57 Kouksundo trainees (34 males and 23 females). Blood samples were collected 30 min before and after Kouksundo practice (25 min for warm-up, 45...
Physiology & Behavior
January 28, 2015
Alexandre J. Oliveira-Lima, Renato Antunes Dos Santos, A.w. Hollais et al.
91 citations
BackgroundHallucinogenic drugs were used to treat alcoholic patients in the past, and recent developments in the study of hallucinogens led to a renewal of interest regarding the application of these drugs in the treatment of addiction. In this scenario, accumulating evidence suggests that the hallucinogenic brew ayahuasca (Aya) may have therapeutic effects on substance abuse problems.MethodsWe...
Physiology & Behavior
May 3, 2011
David M. Compton, Kerri L. Dietrich, Melissa C. Selinger et al.
21 citations
Foxy or Methoxy Foxy (5-methoxy-N,N-di(iso)propyltryptamine hydrochloride; 5-MeO-DIPT) is rapidly gaining popularity among recreational users as a hallucinogenic "designer drug." Unfortunately, much remain unknown about the consequences of its use on neuropsychological development or behavior. During one of two adolescent periods, the rats were given repeated injections of 5 mg/kg or 20 mg/kg...
Physiology & Behavior
August 1, 2006
María E. Reverón, Esther Y. Maier, Christine L. Duvauchelle
23 citations
Hyperthermia and hyperlocomotor activity are commonly reported acute effects of high dose, experimenter-delivered 3,4-methylenedioxymethamphetamine (MDMA). The current investigation was performed to determine short- to long-term physiological and behavioral changes induced by moderate intake MDMA self-administration. In the present study, rats self-administered MDMA (approx. 2.0-7.0 mg/kg/day)...
Physiology & Behavior
1987
T Archer, E Arweström, B G Minor et al.
32 citations
In experiments with both rats and mice the 5-HT agonists 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) and 5-methoxy-N,N-dimethyl-tryptamine (5-MeODMT) were shown to produce reliable analgesic effects after acute administration (1 mg/kg SC) in the tail-flick, hot-plate and shock-titration tests of nociception. Prior treatment with the noradrenaline neurotoxin,...