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A Meta-Analysis of Domestic and International Studies on the Effects of Meditation Programs for Cancer Patients: Focusing on Depression, Anxiety, Pain, and Quality of Life

Do-Hyeok Jang, Sungh-Ho Hwang

Korea Exercise Rehabilitation Welfare Association September 30, 2026 DOI: 10.66298/kerwa.2026.7.3.97 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Meta-analysis Peer reviewed
Population Cancer patients
Intervention Meditation-based interventions
Topics Anxiety Depression Meditation
Key findings Meditation-based interventions were associated with moderate reductions in depression and anxiety and small-to-moderate improvement in quality of life among cancer patients, but no significant effect on pain. The number of sessions moderated anxiety and marginally quality-of-life effects, and cancer type moderated pain effects, though these variables did not fully explain heterogeneity.

Abstract

This meta-analysis aimed to examine the effects of meditation-based interventions on psychological and physical outcomes in cancer patients. A total of 25 studies were included after a systematic literature search. Random-effects models were used to calculate pooled effect sizes (Hedges’ g), and meta-regression analyses were conducted to explore the moderating effects of the number of sessions, session duration, and cancer type (breast versus non-breast cancer). The results showed that meditation interventions were significantly associated with a moderate reduction in negative outcomes overall (Hedges’ g = –0.424, 95% CI [–0.613, –0.235], p < .001). Significant effects were observed for depression (g = –0.399, p = .001) and anxiety (g = –0.436, p = .001), whereas the effect on pain was not statistically significant (g = 0.104, p = .363). Quality of life showed a significant small-to-moderate improvement (g = 0.337, p = .029). Meta-regression analyses revealed that the number of sessions significantly moderated the effect on anxiety (β = 0.033, p = .024), indicating that studies with more sessions tended to show smaller anxiety reduction effects as the number of sessions increased, and marginally moderated the effect on quality of life (β = 0.081, p = .055), suggesting a potential cumulative benefit of additional sessions. In addition, cancer type was a significant moderator of the effect on pain, with non-breast cancer patients showing greater improvements than breast cancer patients. However, the moderator variables did not fully explain the between-study heterogeneity. In conclusion, this meta-analysis provides integrated evidence that meditation interventions are significantly associated with reduced depression and anxiety and improved quality of life among cancer patients. The findings also suggest that intervention effects may vary depending on the number of sessions and cancer type. These results offer practical implications for the design of meditation programs tailored to cancer patients.

Comparable studies

Other systematic reviews and meta-analyses on anxiety, most cited first.

Study Year Design Participants
Meditation Programs for Psychological Stress and Well-being Diverse adult clinical populations 2014 Meta-analysis n = 3,515
Research Review: The effects of mindfulness‐based interventions on cognition and mental health in children and adolescents – a meta‐analysis of randomized controlled trials Children and adolescents 2018 Systematic review and meta-analysis n = 3,666
Therapeutic effects of classic serotonergic psychedelics: A systematic review of modern‐era clinical studies Patients with cancer- or illness-related anxiety and depression, major depressive... 2020 Systematic review n = 188
Does Mindfulness Meditation Improve Anxiety and Mood Symptoms? A Review of the Controlled Research Clinical populations with medical and emotional disorders 2007 Systematic review n = 15
Antidepressive, anxiolytic, and antiaddictive effects of ayahuasca, psilocybin and lysergic acid diethylamide (LSD): a systematic review of clinical trials published in the last 25 years Patients from included clinical trials 2016 Systematic review

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