Page 613 of 857: studies 6,121 to 6,130 of 8,563, newest first. Back to the addiction overview
July 5, 2017 Eric Maisel
Human beings have used chemicals to alter their experience of life since the beginning of time: peyote, magic mushrooms, Scotch, marijuana, cocaine, nicotine, caffeine, heroin, red wine. The list of chemicals used by human beings for the purpose of feeling different is very long. It is only metaphoric—and a profoundly dangerous and ill-chosen metaphor—to call these “medications that treat the...
Psychopharmacology July 2017 Erin M Rock, Cheryl L Limebeer, Gavin N Petrie et al.
Cannabis is commonly used by humans to relieve stress. Here, we evaluate the potential of intraperitoneally (i.p.) administered Δ9-tetrahydrocannabiol (THC) and cannabidiolic acid (CBDA, the precursor of cannabidiol [CBD]) to produce dose-dependent effects on anxiety-like responding in the light-dark (LD) emergence test of anxiety-like responding in rats, when administered acutely or...
Current Psychiatry Reports July 2017 Flavie Waters, Umberto Moretto, Thien Thanh Dang‐Vu
Little is known about the presence of parasomnias such as nightmare disorder, sleep paralysis, REM sleep behavior disorder (RBD), and sleep-related eating disorders (SRED) in people with mental illness. A predominant view suggests that psychotropic medications might be contributing to parasomnias. This article summarizes knowledge regarding the relationships between psychiatric disorders and...
Cerebral Cortex July 1, 2017 P. Tacikowski, Christopher C. Berger, H. Ehrsson
Conceptual self-awareness is a mental state in which the content of one's consciousness refers to a particular aspect of semantic knowledge about oneself. This form of consciousness plays a crucial role in shaping human behavior; however, little is known about its neural basis. Here, we use functional magnetic resonance imaging (fMRI) and a visual masked priming paradigm to dissociate the...
Perichoresis July 1, 2017 Yadav Sumati 6 citations
Abstract Humans have always been and still are fascinated by the elusive phenomenon of soul and have devised various approaches to interpret it and attribute different names to it; depending on which part, which religion, which tribe and which sect of the world they belong to. Theologians to philosophers to spiritual thinkers to literary authors and critics to scientists—all seem to be...
The Journal of Alternative and Complementary Medicine July 1, 2017 Sarah Bowen, Vanessa C Somohano, Rachel E Rutkie et al.
As rates of opiate misuse rise in the United States, so do significant associated health and financial consequences to afflicted individuals, their families, and society at large. Methadone maintenance therapy (MMT) is one evidence-based approach to treating opiate addiction, yet supplemental psychosocial treatment to support this approach is lacking. Mindfulness-based relapse prevention (MBRP)...
Medical Hypotheses July 1, 2017 E Garcia-Rill
Gamma activity has been proposed to promote the feed forward or "bottom-up" flow of information from lower to higher regions of the brain during perception. The pedunculopontine nucleus (PPN) modulates waking and REM sleep, and is part of the reticular activating system (RAS). The properties of PPN cells are unique in that all PPN neurons fire maximally at gamma band frequency regardless of...
Psychopharmacology July 1, 2017 Rainer Kraehenmann, Dan Pokorný, Leonie Vollenweider et al.
Rationale Accumulating evidence indicates that the mixed serotonin and dopamine receptor agonist lysergic acid diethylamide (LSD) induces an altered state of consciousness that resembles dreaming. Objectives This study aimed to test the hypotheses that LSD produces dreamlike waking imagery and that this imagery depends on 5-HT2A receptor activation and is related to subjective drug effects....
Forensic Toxicology July 1, 2017 Genri Kawahara, Hideyuki Maeda, Ruri Kikura-Hanajiri et al. 17 citations
N -Benzyl-substituted 2C class phenethylamines (NBOMes) are psychoactive designer drugs, with strong hallucinogenic and stimulant effects, even at low doses. The designer drug, 2-(4-bromo-2, 5-dimethoxyphenyl)- N -(2-methoxybenzyl) ethanamine (25B-NBOMe) is considered to be one of the most potent agonists of the serotonin-2A (5-HT_2A) receptor. Recently, we reported the first lethal case of...
Neurotoxicity Research July 1, 2017 Jana Ruda-Kucerova, Zuzana Babinska, Tibor Stark et al. 26 citations
Ketamine may prove to be a potential candidate in treating the widespread drug addiction/substance abuse epidemic among patients with schizophrenia. Clinical studies have shown ketamine to reduce cocaine and heroin cravings. However, the use of ketamine remains controversial as it may exacerbate the symptoms of schizophrenia. Therefore, the aim of this study is to characterize the effects of...