BACKGROUND: Investigations of the electrophysiology of gaseous anesthetics xenon and nitrous oxide are limited revealing inconsistent frequency-dependent alterations in spectral power and functional connectivity. Here, the authors describe the effects of sedative, equivalent, stepwise levels of xenon and nitrous oxide administration on oscillatory source power using a crossover design to...
Abstract: Introduction: This study examines the effectiveness of integrating mindfulness-based techniques within therapy for women suffering to achieve orgasm. Although widely applied in psychotherapy, this approach has only recently been introduced in the treatment of female sexual dysfunction. Aim: To compare the effectiveness of a video-based self-administered treatment, rooted within the...
The chapter follows Jacques Derrida’s development from one end of his career to its conclusion and argues that the whole project of deconstruction must be understood in relation to the concept of worldlessness. The first part of the chapter is concerned with Derrida’s critique of Edmund Husserl. Derrida argues that the phenomenological concept of worldlessness is based on the auto-affective...
AbstractThe present paper argues that experimental phenomenology has an important role to play in research on mindfulness. Experimental phenomenology is defined as a subcategory of phenomenology (defined as the science of our subjective experience of being in the world), which explores the effects of intentional variations of subjective experiencing (direction of attention and choice of...
Background: Nitrous oxide (N2O) has been used in clinical and recreational settings for over 150 years. Through inactivation of the Vitamin B12 dependent enzyme, methionine synthase, N2O can lead to the development of peripheral neuropathy. This study sought to determine the relationship between the exposure and risk of neurological symptoms in the largest ever sample of users. Design: Data are...
Though there was initial interest in the use of psychedelic drugs for psychiatric treatment, bad outcomes and subsequent passage of the Substance Act of 1970, which placed psychedelic drugs in the Schedule I category, significantly limited potential progress. More recently, however, there has been renewal in interest and promise of psychedelic research. The purpose of this review is to...
This study consists of a description on pre-reflexive processes in learning how to fight. The objective of this investigation is to present and discuss them through phenomenology as a philosophical and methodological point of view. It is a way to comprehend each phenomenon from its own structure, not apart from the reality of those who live it. In embodied corporal practices, the body...
Alexander Dawson has produced a stellar piece of comparative scholarship on the history of peyote and its uses in both Mexico and the United States. He opens his book with an 1833 cholera epidemic that plagued a small town in northern Mexico and the attempt by a pioneering doctor to use local remedies to solve the crisis. This introductory chapter paves the way for the multifaceted remainder of...
Access of sensory information to consciousness is thought to be mediated through ignition of neural activity in the prefrontal cortex (PFC). Ignition occurs once activity elicited by sensory input crosses a threshold, which has been shown to depend on brain state fluctuations. However, the neural correlates of fluctuations and their interaction with the neural representations of conscious...
Mephedrone (4-MMC, mephedrone) is a synthetic cathinone derivative included in the class of new psychoactive substances. It is commonly used simultaneously with alcohol (ethanol). The aim of the present study was to evaluate the interactions on subjective, cardiovascular and hormone effects and pharmacokinetics between mephedrone and alcohol in humans. Eleven male volunteers participated as...