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The Journal of Sexual Medicine

ISSN 1743-6095, 1743-6109

13 papers in the library · 21 citations · publishing 2008-2026

Papers

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(107) Chemsex: The Neuropharmacology of Pleasure and Risk

The Journal of Sexual Medicine June 1, 2026 M Almada, R Neto, A Pinto et al.

Abstract Introduction Emerging in the late 1990s within sexualized contexts, chemsex-the intentional use of psychoactive substances to enhance or prolong sexual activity-has evolved from a niche practice to a globally recognized public health concern, particularly among LGBTQ populations and men who have sex with men (MSM). Early accounts involved 3,4-methylenedioxymethamphetamine (MDMA) and...

DOI: 10.1093/jsxmed/qdag118.094 (opens in new tab) Full text (opens in new tab) Pleasure Public health Neuropharmacology Disease +9

Psychedelic research and sexuality: opportunities and pitfalls.

The Journal of Sexual Medicine February 1, 2026 Hendrikus Knegtering, Thalia Herder, Nynke Boonstra et al.

Psychedelic-assisted therapy (PAT) is increasingly investigated as a treatment for depression, post-traumatic stress disorder (PTSD), and substance use disorder. In the United States (US) and European Union, esketamine has been approved for the treatment of depression, while psilocybin and 3,4-methylenedioxymethamphetamine (MDMA) have received Breakthrough Therapy Designation in the US for...

DOI: 10.1093/jsxmed/qdag025 (opens in new tab) Psychedelic-assisted therapy Sexual function Sexual dysfunction Psychedelics

(PNM-42) Use of psychedelic drugs as an adjunct in couples psychotherapy and sex therapy

The Journal of Sexual Medicine February 1, 2026 F. Pereira, E. Cruz

Despite clinical investigations with psychedelics for severe cases of mood disorders and PTSD and current research suggesting such applicability, research on their application in couples therapy and sex therapy is scarce. The objective of this systematic review was to highlight these drugs as adjuvants for such patients. Literature research was conducted using the terms “couple’s therapy” or...

Mindfulness and daily sexual function: a dyadic diary study.

The Journal of Sexual Medicine July 22, 2025 Emily Jarvis, Jackie S Huberman, Natalie O Rosen

Difficulties with sexual function are common with implications for couples' psychological and relationship well-being. Sexual mindfulness (ie, non-judgmental present-moment awareness during sexual activity) has been positively linked to sexual function in cross-sectional studies, but associations in the context of couples' daily lives are lacking. The aim of this study was to determine if...

Homework adherence in mindfulness-based cognitive interventions for female sexual dysfunction: a scoping review.

The Journal of Sexual Medicine October 1, 2024 Fernanda Rafaela Cabral Bonato, Nicolas De Oliveira Cardoso, Lori A Brotto

Background: Mindfulness-based cognitive therapy (MBCT) includes regular home practice of mindfulness exercises as a key means of cultivating mindfulness. Although there are instruments available for measuring homework adherence following cognitive behavioral therapy (CBT), little is known about measuring homework practice in MBCT studies for sexual dysfunction. Aim: In this review we sought to...

DOI: 10.1093/jsxmed/qdae108 (opens in new tab) Full text (opens in new tab) Humans Patient compliance Sexual dysfunctions, psychological Sexual dysfunction, physiological +4

A virtual, group-based mindfulness intervention for midlife and older women with low libido lowers sexual distress in a randomized controlled pilot study

The Journal of Sexual Medicine June 23, 2023 Holly N Thomas, Lori A Brotto, Flor de Abril Cameron et al. 21 citations

BACKGROUND: Distressing low libido is common among women and has significant negative impacts; mindfulness has shown promise to increase sexual desire in women with low libido, but existing interventions are not tailored to midlife and older women. AIM: We adapted a mindfulness intervention to meet the needs of this population and conducted a pilot randomized controlled trial to assess...

(267) Ecstasy' - Accurate or Deceptive Name? A Systematic Review of MDMA Effects on the Male Sexual Response Cycle

The Journal of Sexual Medicine May 1, 2023 Julie Suyama, Alexandra Dubinskaya, Karyn Eilber et al.

3,4-Methylenedioxymethamphetamine (MDMA, ‘Ecstasy’ or ‘Molly’) is a synthetic psychostimulant and entactogenic drug of abuse that augments feelings of pleasure, increases energy, and distorts sensory perception. MDMA increases serotonin, dopamine, and norepinephrine neurotransmission within the mesolimbic reward pathway, which impacts human sexual function. While dopamine is implicated as a...

009 Predictors of Altered States of Consciousness Triggered by Sexual Activity

The Journal of Sexual Medicine May 1, 2022 R. Costa, Jacopo Ellero

ABSTRACT Introduction Altered states of consciousness (ASCs) refer to marked changes in usual waking consciousness. Sexual arousal, orgasm, and resolution, are modulated by neural pathways that are also activated by psychoactive substances that trigger ASCs. Relatedly, self-report studies show that sexual activity may trigger ASCs. However, investigation about sex-related ASCs is scarce. More...

A Randomized Study Comparing Video-Based Mindfulness-Based Cognitive Therapy With Video-Based Traditional Cognitive Behavioral Therapy in a Sample of Women Struggling to Achieve Orgasm

The Journal of Sexual Medicine February 1, 2020 Françoise Adam, Pascal De Sutter, James Day et al.

Abstract: Introduction: This study examines the effectiveness of integrating mindfulness-based techniques within therapy for women suffering to achieve orgasm. Although widely applied in psychotherapy, this approach has only recently been introduced in the treatment of female sexual dysfunction. Aim: To compare the effectiveness of a video-based self-administered treatment, rooted within the...

How Cannabis Alters Sexual Experience: A Survey of Men and Women.

The Journal of Sexual Medicine November 1, 2019 E. Wiebe, Alanna Just

INTRODUCTION Cannabis is reported to enhance sexual function; yet, previous studies have shown that physiological and subjective indices of sexual arousal and motivation were associated with decreased availability of circulating endocannabinoid concentrations. AIM To explain this contradiction, we evaluated which aspects of sexual experience were enhanced or diminished by cannabis use. METHODS...

A Systematic Review on Mindfulness Meditation-Based Interventions for Sexual Dysfunctions.

The Journal of Sexual Medicine October 1, 2019 Izabela Jąderek, Michał Lew‐Starowicz

INTRODUCTION Mindfulness-based therapies (MBT) are more and more frequently used in the treatment of sexual dysfunctions; therefore, it seems very important to assess evidence-based data on the clinical efficacy of these interventions. AIM To provide a systematic review of published studies into the efficacy of MBT in the treatment of sexual dysfunctions. METHODS The material for the analysis...

A Comparison of Mindfulness-Based Cognitive Therapy Vs Cognitive Behavioral Therapy for the Treatment of Provoked Vestibulodynia in a Hospital Clinic Setting.

The Journal of Sexual Medicine June 1, 2019 Lori A Brotto, S. Bergeron, Bozena Zdaniuk et al.

INTRODUCTION Chronic and distressing genito-pelvic pain associated with vaginal penetration is most frequently due to provoked vestibulodynia (PVD). Cognitive behavioral therapy (CBT) significantly reduces genital pain intensity and improves psychological and sexual well-being. In general chronic pain populations, mindfulness-based approaches may be as effective for improving pain intensity as...

A mindfulness-based group psychoeducational intervention targeting sexual arousal disorder in women.

The Journal of Sexual Medicine July 2008 Lori A Brotto, Rosemary Basson, Mijal Luria

Despite their widespread prevalence, there are no existing evidence-based psychological treatments for women with sexual desire and arousal disorder. Mindfulness, the practice of relaxed wakefulness, is an ancient eastern practice with roots in Buddhist meditation which has been found to be an effective component of psychological treatments for numerous psychiatric and medical illnesses. In...