Abstract Background The Yaqui Intercultural Medicine Clinic was established in 2020 to provide accessible, culturally-attuned treatment for substance use and mental health disorders among an Indigenous Yaqui community in Mexico. The treatment program integrates ayahuasca ceremonies and psychotherapeutic support within a community-based outpatient treatment service. This observational pilot...
January 23, 2025Talha Imtiaz, Ehsan Ali, Muhammad Farooq Azhar
San Pedro cactus (Echinopsis pachanoi), also known as (Trichocereus pachanoi) belongs to the family Cactaceae it is identified by its tall, columnar, blue-green stems with 6–8 columns and spaced areoles that produce up to seven spines of yellowish to brown color. It can grow up to 6 m tall with multiple branches, producing highly fragrant, white nocturnal flowers. This fast-growing cactus is...
Recent research on the potential therapeutic value of psychedelic substances has led to changes in media representation and drug policy in some U.S. states. Yet, little is known about lay perceptions of these substances. The current study aimed to describe health perceptions of psychedelic substances, test differences in perceptions of therapeutic vs. recreational use of psychedelic substances,...
Background and Clinical Significance: Treatment resistant psychiatric disorders affect millions of people across the globe. Ketamine has been employed as a treatment option for those with treatment resistant depression, as well as for chronic pain and alcohol use disorder. However, case presentations and research has been limited on the outcomes, and furthermore there is even less on the...
Background: Psilocybin is a natural alkaloid with therapeutic potential in the treatment of different mental disorders. Bibliometric information on its use is still scattered in the literature. Objective: To investigate the temporal and bibliometric patterns of publications and the specificity of psilocybin in the treatment of mental disorders. Method: Performed a bibliometric analysis using...
There is increasing evidence of ketamine's therapeutic potential in reducing substance use in individuals with substance use disorders. However, its effects on tobacco use disorder are unknown. We investigated the effect of a subanesthetic dose of ketamine on tobacco use. This randomized, single-blind, placebo-controlled, pilot study administered intravenous ketamine to individuals with tobacco...
MDMA or 3,4- methylenedioxymethamphetamine is a psychoactive substance, exhibiting mild hallucinogenic properties, that became widely known as a recreational party drug. However, its ability in helping individuals access deeply rooted emotions has prompted significant interest in its potential applications within clinical practice. MDMA’s mechanism of action involves increasing the release of...
This paper critically evaluates the concept of saṅkhāra within early Theravāda Buddhist knowledge, addressing gaps in prior studies by Bandusena Wickranmasinghe Dadanayaka and Venerable Nodhiñana, who primarily emphasize the doctrinal and causal aspects of saṅkhāra without substantial engagement with its psychological implications. This research focuses on saṅkhāra’s role as “mental formations”...
This exploratory study examines the effects of a single, brief (3-h) Chamber Restricted Environmental Stimulation Therapy (REST) session on emotional experience, state mindfulness, and physiological regulation in young adults. Previous research has shown preliminary evidence, that REST offers a range of benefits in managing stress and mental well-being. We focused on young adult population, a...
Postoperative cognitive dysfunction (POCD) is characterized by a decline in cognitive functions, including memory, attention, and executive abilities, following surgery, with no effective therapeutic drugs currently available. Arketamine, the (R)-enantiomer of ketamine, has shown promise in mitigating cognitive deficits in animal models. In this study, we investigated whether arketamine could...