Emerging psychedelic research highlights the therapeutic potential and broader positive psychological transformation of psychedelic-assisted therapy. While naturalistic studies support these outcomes, gaps remain in understanding the specific nature of perceived benefits and in the availability of validated instruments to assess them. This study aimed to develop and validate the Perceived...
Insomnia is a prevalent sleep disorder characterised by difficulty initiating or maintaining sleep, which significantly impacts both physical and mental health. Pharmacological treatments, while effective, pose risks of side effects and dependency. Meditation, a mind-body practice with ancient roots, has emerged as a promising, non-pharmacological intervention for managing insomnia.This review...
Rather than a passive reflection of nociception, pain is shaped by the interplay between one's experiences, current cognitive-affective states, and expectations. The placebo response, a paradoxical yet reliable phenomenon, is postulated to reduce pain by engaging mechanisms shared with active therapies. It has been assumed that mindfulness meditation, practiced by sustaining nonjudgmental...
Artificial intelligence (AI) has made some remarkable advances in recent years, particularly within the area of large language models (LLMs) that produce human-like conversational abilities via utilizing transformer-based architecture. These advancements have sparked growing calls to develop tests not only for intelligence but also for consciousness. However, existing benchmarks assess...
In accordance with Bud (A.D.) Craig's theories, we maintain that ascending physiological signals in their temporal dynamics are a necessary prerequisite for human time judgments. Functional neuroimaging and psychophysiological evidence have increasingly demonstrated that the subjective judgment of time is based on the physical and emotional self. The psychological literature reveals how...
The last few years have seen exponential growth in interest, investment, advocacy, and research into psychedelics as therapeutics. This reflects an optimism about the potential promise of psychedelics as therapeutics. As with all therapeutic interventions, research is needed not only into their benefits but also potential risks. Indeed, when substances with therapeutic potential are scrutinized...
After a dormant period of over 30 years, research into the use of traditional as well as some non-traditional psychedelics has enjoyed a resurgence around the world. This paper investigates the biological and psychological operations of psychedelics, comparing its, merits relative to other mental health care approaches. This form of therapy is unique in that it aims to heal, rather than merely...
Frontiers in Psychiatry2025Rebecca Paetow, Maike Franziska Dohrn, Michelle Finner-Prével et al.
Nitrous oxide (N2O) is used for anesthetic purposes but has gained popularity as a recreational substance. Despite its potentially severe adverse effects, knowledge about N2O use within psychiatric populations is limited. This study aimed to evaluate the life-time prevalence and patterns of N2O consumption among patients with psychiatric disorders. A retrospective observational cohort study was...
This epilogue synthesizes Gnostic cosmology, the "ontological turn" in anthropology, and systems theory to present a rigorous diagnostic framework for the converging crises of the modern era. The text posits that our current geopolitical and psychological malaise is not merely a series of policy failures, but the manifestation of a fundamental ontological war - a struggle over the nature of...
Methamphetamine is a common addictive industrial substance. Medicinal plants such as Artemisia absinthium L. with anti-inflammatory, antioxidant, analgesic, neuroprotective, antidepressant, and antipyretic properties may help patients reduce withdrawal syndrome symptoms. Five treatment groups received intraperitoneal (i.p.) injections of 3,4-methylenedioxymethamphetamine (MDMA) and an ethanolic...