Ketamine therapy is effective in alleviating symptoms of psychiatric disorders such as depression and anxiety; however, its increasing recreational use raises concerns about potential abuse. Hericium erinaceus mycelium, which contains the bioactive compound erinacine A, has shown promise in promoting brain health. This study investigated whether H. erinaceus mycelium and erinacine A could...
This research project presents a six-year autoethnographic case study examining recurrent sleep paralysis through the lens of lived experience. While sleep paralysis is commonly explained through neurophysiological mechanisms—particularly REM atonia intrusion—there remains a significant gap in qualitative literature capturing how the condition is experienced subjectively over time. The purpose...
2026Sanaz Pourgoli, Maryam Dehghan, Kamran Pourmohammad Ghouchani et al.
Objective: The purpose of this study was to investigate the effect of compassion-based acceptance and commitment integrated therapy on reducing cortisol hormone levels and improving mindfulness in infertile women undergoing hormone therapy. Methods and Materials: This study employed a quasi-experimental design with a pretest–posttest control group. The statistical population consisted of...
Functional connectomes (FCs) derived from fMRI are unique to an individual and can be reliably distinguished from those of others. However, the neurobiological basis for this "fingerprint"-like uniqueness remains unclear. One hypothesis holds that FC fingerprinting reflects idiosyncratic conscious experiences, while an alternative suggests that stable, intrinsic brain functional network...
The clinical use of psychedelic substances and Psychedelic-Assisted Therapy (PAT) is an area of growing interest that also raises significant social concerns and controversy. Despite existing legal restrictions, empirical research on substances such as psilocybin, mescaline, MDMA, LSD, DMT, and ibogaine has been developing, particularly in the treatment of conditions such as treatment-resistant...
Spirituality has long been recognized as a fundamental dimension of human health and well-being, yet its integration into mental health frameworks remains limited. This essay explores how spirituality is experienced as a coping resource for mental well-being, highlighting mechanisms through which spiritual and religious practices support emotional regulation, resilience, and a sense of purpose....
The global burden of chronic diseases and mental health disorders has intensified the need for holistic interventions such as yoga. Isha Yoga, a comprehensive system integrating physical postures, breathwork, and meditation, has demonstrated preliminary benefits in stress reduction and physiological regulation. This systematic review evaluates the effects of Isha Yoga practices on mental and...
Ciprofol is a novel GABAergic intravenous anesthetic with a rapid onset and favorable safety profile; however, the neural mechanisms underlying the induction and reversal of unconsciousness remain unclear. Electroencephalogram (EEG) microstates provide millisecond-scale markers of large-scale brain network dynamics and may reveal frequency-specific signatures of ciprofol' s effects on...
Consciousness has long been a focus of philosophical inquiry. Philosophers have employed thoughts supported by language and logic as a primary tool to examine the essence and structure of consciousness in mostly adult humans. Language elevates the abstraction of thought and has significantly contributed to the advancement of civilization. Within an individual, language plays a significant role...
Spiritual care occupations-spiritual direction and professional chaplaincy chief among them-occupy a professional jurisdiction whose cognitive foundation is not a body of techniques but an ontological commitment: the claim that the phenomena they address (vocation, discernment, encounter, the experience of being addressed by something exceeding the self) are real in a manner not exhaustively...