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Addiction: all studies

Page 17 of 855: studies 161 to 170 of 8,547, newest first. Back to the addiction overview

Research

Are Psychedelics Effective for Treating Substance Use Disorders?

May 28, 2025 David A. Gorelick

Current evidence remains insufficient to support the use of psychedelics for substance use disorders in routine clinical practice. Psilocybin has the most supportive data for alcohol use disorder, though it is of moderate quality. The evidence quality is generally low, with significant risk of bias due to poor blinding. Only half of identified studies were RCTs, with 44% conducted over 50 years...

The correlation between mindfulness and relapse prediction in individuals with substance use disorder: a cross-sectional study from Turkey.

Journal of ethnicity in substance abuse May 23, 2025 Sinem Aytop, Maral Kargin

The aim of this study is to examine the correlation between mindfulness and relapse prediction in individuals with substance use disorder. The study was conducted on individuals who were diagnosed with substance use disorders and were receiving at the psychiatry outpatient clinic of a university hospital in Turkey. In the study, 193 individuals with substance use disorders were reached. The...

Race/ethnicity moderates the associations between lifetime psilocybin use and opioid use disorder

PLoS One May 7, 2025 Grant Jones 2 citations

Background: Opioid use disorder (OUD) is a debilitating health condition that is associated with significant morbidity and mortality in the U.S. While preliminary studies have demonstrated that psilocybin is associated with lowered odds of OUD, current research in this domain suffers from a lack of investigation into the impact of race/ethnicity on this association. Objective: To assess the...

Evaluating the Effectiveness of Psychedelic-Assisted Therapy in Treating Alcohol Use Disorders: A Review

Alcoholism Treatment Quarterly May 2, 2025 Ritika Shah, Ashish Sarangi

ABSTRACT Background Alcohol Use Disorder (AUD) is a widespread condition with serious health, social, and economic impacts, often marked by relapse despite the availability of FDA-approved treatments. Recent studies suggest that psychedelic substances, such as psilocybin, Lysergic acid diethylamide (LSD), ayahuasca, etc. may offer novel therapeutic potential in treating AUD by modulating...

Recreational Ketamine Use among Individuals with Opioid Use Disorder: Demographics, Motivations, and Polysubstance Use.

Substance Use & Misuse May 1, 2025 Corinne L Chandler, Mance E Buttram, Matthew S Ellis 1 citation

Data show that recreational ketamine use appears to be increasing. This study aimed to understand how ketamine fits into broader polysubstance use in individuals with opioid use disorder (OUD). Survey data were collected from a sample of treatment-seeking individuals with OUD in March 2022. Of 301 respondents, 28.6% reported lifetime ketamine use. Ketamine use was more frequently reported among...

A Comparison of the Effectiveness of Group Counseling Based on Mindfulness-Based Cognitive Therapy and Metacognitive Therapy on Academic Procrastination and Internet Addiction among High School Students

پژوهش‌های کاربردی روانشناختی April 26, 2025 Hossein Ilanloo, Sedigheh Ahmadi, Kianoosh Zahrakar

The objective of the current investigation was to evaluate the efficacy of group counseling that is based on mindfulness-based cognitive therapy and metacognitive therapy in the context of academic procrastination and internet addiction among high school students. A control group was included in the study, which employed a quasi-experimental design with a pretest-posttest-follow-up approach...

DOI: 10.22059/japr.2025.337055.644161 (opens in new tab) Full text (opens in new tab) Academic procrastination Group counseling Internet addiction Metacognitive therapy +1

Adjunctive ketamine vs. buprenorphine in co-occurring major depressive disorder and opioid use disorder: a randomized, double-blind clinical trial assessing anxiety symptom severity and craving intensity.

Trials April 17, 2025 Arash Mansoori, Amir Bazrafshan, Jamshid Ahmadi et al. 4 citations

The concomitant presence of major depressive disorder (MDD) and opioid use disorder (OUD) poses a formidable clinical challenge, warranting effective interventions that address both psychiatric and addictive components. This study sought to compare the efficacy of adjunctive ketamine and buprenorphine in mitigating anxiety symptom severity and craving intensity in individuals with co-occurring...

Rare but relevant: Ketamine-induced cystitis - an in-depth review for addiction medicine.

Addiction April 4, 2025 Asem Abdelrahman, Mo Belal 4 citations

Ketamine-induced cystitis is an increasingly recognized complication associated with the addictive use of ketamine, a dissociative anesthetic. This article provides a comprehensive overview, focusing on its pathophysiology, clinical presentation, diagnosis, management strategies, and implications for addiction treatment. The British Association of Urological Surgeons consensus serves as a...

DOI: 10.1111/add.70052 (opens in new tab) Full text (opens in new tab) Ketamine bladder dysfunction Ketamine cystitis Ketamine uropathy Ureteric stricture +6

Ketamine-Assisted Psychotherapy for Addiction: Mechanisms, Evidence, and Clinical Implications

April 1, 2025 Ryan D Ward

Substance use disorders (SUDs) are notoriously difficult to treat due to complex biopsychosocial underpinnings and high relapse rates. Recent evidence positions ketamine-assisted psychotherapy (KAP) as a promising intervention for treatment-resistant addiction. This review explores ketamine’s neurobiological mechanisms, its synergistic effect with psychotherapy, and clinical data supporting its...

Mindful Self-Compassion for Veterans with Morally Injurious Experiences and Co-Occurring Posttraumatic Stress Disorder and Substance Use Disorder: A Feasibility Study.

Journal of dual diagnosis April 1, 2025 Erica Eaton, Christy Capone, Shannon Reese et al. 2 citations

Objective: This study evaluates the feasibility and acceptability of delivering Mindful Self-Compassion (MSC) to veterans with moral injury and co-occurring PTSD and substance use disorder (PTSD-SUD). Methods: Veterans (N = 26; M age = 50.92; 100% male) were recruited for an 8-week MSC group. Participants completed measures of self-compassion, guilt, shame, PTSD, and substance use outcomes at...