Abstract Background and aims This is the first systematic review of the extant literature on all major psychedelic‐assisted treatment for alcohol use disorder (AUD), tobacco use disorder (TUD) and other substance use disorders (SUD). We aimed to summarise the evidence for efficacy of psychedelic‐assisted treatment for AUD, TUD, and SUD; to evaluate its quality; and to offer recommendations for...
Addiction medicine is confronting challenges brought about by changes in our modern world, including shifts in the drug market and the increasing digitalization of our environments. This article highlights some of these challenges and explores potential strategies to address them. The field is also advancing through robust research momentum in psychedelic-assisted psychotherapy. Additionally,...
The current opioid crisis has had an unprecedented public health impact. Approved medications for opioid use disorder (OUD) exist, yet their limitations indicate a need for innovative treatments. Limited preliminary clinical studies suggest specific psychedelics might aid OUD treatment, though most clinical evidence remains observational, with few controlled trials. This review aims to bridge...
Smartphone Addiction (SA) is a rising global behavioral issue among adolescents. Extant studies rarely explore interventions to lower the risk of SA and increase resilience for adolescents. To investigate the feasibility of the study protocol designed with a cluster-RCT and examine the preliminary effect of the first 4-week group mindfulness-based cognitive program (MBCP) on Smartphone...
This article examines the question of whether living beings possess an innate, unchangeable nature or have the capacity for fundamental transformation—a question with profound implications for treating addiction-related physical illness. By integrating diverse perspectives from religious and philosophical traditions, mystical thought, modern neuroscience, genetics, and clinical approaches to...
Objective: Previous studies claim a healing effect on psychological and medical symptoms beyond the biopsychosocial construct of medicine to include a “spiritual” aspect with added experience of wholeness and well-being. A recommendation for the development of a human ontological model for research of this spiritual domain has been suggested. The objective of this study was to test feasibility...
Despite decades of neuroscience research and significant investment in addiction neuroimaging, clinical outcomes for individuals with substance use and behavioural addictions remain poor. Only 1.8% of people with substance use disorders receive effective treatment, highlighting a major disconnect between mechanistic understanding and clinical utility. This paper calls for a reorientation of...
Psychedelic-assisted therapy is a remarkably promising treatment for substance use disorders and for alcohol use disorder (AUD) in particular. Research supporting psychedelics as a safe and effective pharmacotherapy for AUD and its comorbid psychiatric conditions dates from the late1940s and includes over 2,000 published studies. There are, however, challenges to the clinical implementation of...
Substance use disorders (SUDs), including alcohol, opioid, and cocaine dependencies, present significant challenges in public health. Current treatment modalities often face limitations in efficacy and accessibility, necessitating exploration of novel therapeutic approaches. Ketamine, originally recognized for its anesthetic properties, has garnered attention for its potential in treating SUDs...
Psychedelic therapies have emerged as a modality of treatment for several treatment resistant diseases, including post-traumatic stress disorder (PTSD), treatment resistant depression, substance use disorders, anxiety, and obsessive-compulsive disorders. Arguably more than with other therapies, their success is dependent on the facilitator and the context of the administration. Several programs...