Mini-Reviews in Medicinal Chemistry
September 18, 2026
Fatemeh Abolhasani, Hojjat Rezaiezadeh, Mohammad Amin Langarizadeh et al.
Psilocybin, a compound found in certain species of Psilocybe mushrooms, shows potential as a treatment for various psychiatric conditions. In the past decade, a growing body of evidence has shown the effectiveness of psilocybin in treating conditions, such as treatment-resistant depression, generalized anxiety disorder, post-traumatic stress disorder, and substance use disorders. This review...
Journal of Psychoactive Drugs
September 18, 2026
Suzana Mat Isa, Aini Ismafairus Abd Hamid, Muhamad Zabidi Ahmad et al.
), further studies are needed to measure its neurobiological impacts. This exploratory study employed resting-state functional magnetic resonance imaging (rs-fMRI) to examine alterations in brain activity and functional connectivity (FC) among kratom users. A total of 43 respondents were recruited (22 regular kratom users and 21 healthy controls). RS-fMRI data were acquired using a 1.5T GE...
Zenodo (CERN European Organization for Nuclear Research)
September 18, 2026
Morteza Niami
preprint
Abstract: Intensity has occupied a significant position in modern and contemporary philosophy, particularly in accounts of duration, affect, difference, embodiment, becoming, and material transformation. From Bergson’s analysis of qualitative multiplicity and duration to Deleuze’s ontology of intensive difference, and from phenomenological accounts of lived affectivity to contemporary...
Behavioral and Brain Sciences
September 17, 2026
Eva Jablonka, Simona Ginsburg, Zohar Z Bronfman
Seth's claim that only biological or biological-like systems can be conscious leaves open the question of what renders only some organisms conscious. We address this question by pointing to the material, ontogenetic, memory, and evaluative affordances of living organisms and arguing that evolved, minimal consciousness requires complex cognitive-affective architecture for which these biological...
Psychiatry and Clinical Neurosciences
September 17, 2026
T Nakamura, Matthias Michel, Hakwan Lau
Disturbances of conscious experience are central features of many psychiatric and mental health disorders. Experimental studies of conscious perception are therefore increasingly cited in clinical and translational work under the assumption that they identify neural mechanisms specific to subjective experience. Over the past decades, recording and analysis techniques have advanced substantially...
Cells
September 17, 2026
Katarzyna Lipke, Agnieszka Piwowar
Formerly recognized as an opioid receptor, the sigma-1 receptor (σ1R) is a multifunctional chaperone protein that plays a crucial role in regulating neuronal signaling, neuroprotection, and synaptic plasticity. Increasing evidence highlights a tight functional association between the σ1R and the N-methyl-D-aspartate receptor (NMDAR), a central mediator of excitatory neurotransmission and...
Frontiers in Computational Neuroscience
September 17, 2026
A. K. Pradeep
Human conscious thought often appears as a diffuse, unstable, and only partly verbalizable field until attention, questioning, decision, or speech stabilizes it into a reportable form. This manuscript develops a quantum-inspired neural framework for that transition. The proposal does not claim that consciousness literally depends on microscopic quantum computation, that the brain implements a...
ادبیات عرفانی
September 17, 2026
Haniye Pakravan, Ehsan Reisi
Ecstatic rituals are regarded as among the oldest religious concepts across diverse cultures. These rituals occupy a central and foundational position within certain spiritual traditions and belief systems, while in other religious or cultural contexts, they are rejected or marginalized. In several intellectual and faith-based traditions, trance is understood as a form of altered consciousness...
Warwick Research Archive Portal
September 15, 2026
Erol Čopelj
This work develops a phenomenological account of mindfulness, and related phenomena. It is divided into two main parts. The aim of part one is to articulate a pre-phenomenological sketch of mindfulness (and related phenomena) by (1) drawing on passages from some of the classic works of Western literature and everyday life, (2) through an interpretation of the Satipaṭṭhāna Sutta and (3) by the...
Thoughts Review
September 15, 2026
Oshaque Ali
Scholarship on Shah Abdul Latif Bhittai (1689–1752) recognises him as a vernacular Sufi poet of eighteenth-century Sindh, while studies of Karbala have examined its enduring ethical, ritual, political, and mystical significance. However, the relationship between Karbala and Latif’s poetic tradition remains comparatively underexplored. Existing studies often discuss Sur Kedaro as a lament for...