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Mini-Reviews in Medicinal Chemistry

ISSN 1875-5607, 1389-5575

3 papers in the library · publishing 2026

Papers

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Exploring the Therapeutic Potential of Psilocybin: A Comprehensive Review of Clinical Trial Evidence and Implications for Rescheduling

Mini-Reviews in Medicinal Chemistry September 18, 2026 Fatemeh Abolhasani, Hojjat Rezaiezadeh, Mohammad Amin Langarizadeh et al.

Psilocybin, a compound found in certain species of Psilocybe mushrooms, shows potential as a treatment for various psychiatric conditions. In the past decade, a growing body of evidence has shown the effectiveness of psilocybin in treating conditions, such as treatment-resistant depression, generalized anxiety disorder, post-traumatic stress disorder, and substance use disorders. This review...

Beyond a Psychotropic Plant: Exploring the Ethnomedicinal Value of Anadenanthera colubrina var. cebil.

Mini-Reviews in Medicinal Chemistry March 30, 2026 Romina Belen González, Gonzalo Adrián Ojeda, Ana Melissa González Miragliotta et al.

Anadenanthera colubrina var. cebil (Griseb.) is an ecologically adaptable species native to South America, thriving across a variety of ecosystems, including the dry forests and savannas of Brazil, Argentina, Paraguay, and Bolivia, as well as the Andean highlands of Peru and Chile. Beyond its ecological significance, A. colubrina var. cebil is noted for its traditional use in ethnomedicine and...

Psilocybin: Chemical Foundations and Emerging Therapeutic Potential.

Mini-Reviews in Medicinal Chemistry March 24, 2026 Shivaputra A Patil, Holly C Hunsberger

Psilocybin, chemically known as (4-phosphoryloxy-N, N-dimethyltryptamine, 4-PODMT), is derived from the psychoactive mushroom genus, Psilocybe. Of the four active metabolites, psilocin readily enters systemic circulation. The psychoactive effects of psilocin are thought to arise through partial agonist effects at the 5-HT2A receptor. Psychedelic drugs, including psilocybin, are having a...