European Journal of Pharmacology
September 15, 2026
Anna Brancato, Martina Cicero, Valentina Castelli et al.
Stress is a major determinant of psychopathology, with coping and cognitive impairment arising from abnormal glucocorticoid activity and brain-derived neurotrophic factor (BDNF)-dependent neuroplasticity in the hippocampus. The endocannabinoid system modulates stress and hippocampal functioning since early development, thus its early-life disruption may program vulnerability to stress-related...
Zenodo (CERN European Organization for Nuclear Research)
September 15, 2026
Ivanna J. Joseph, Adam Schiavi, Dylan Bruschi
preprint
We propose a falsifiable framework in which the benefit of transcranial direct current stimulation (tDCS) during contemplative training depends on the practice being performed. Focused attention (FA), open monitoring (OM), and loving-kindness/compassion (LK) engage overlapping networks with potentially different functional emphases. We hypothesize that FA benefits more from a...
Filosofia Unisinos
September 15, 2026
Róbson Ramos Dos Reis
In this paper, I propose a collaborative approach to analysing the phenomenal experience of episodic remembering, bringing together contemporary phenomenology of existential feelings with metacognitive approaches to the feeling of pastness. I explore the issue of how existential feelings, through their pre-intentional function, can constitute the intentionality and valence of the epistemic...
Research, Society and Development
September 15, 2026
João Acyr Chueiry Filho, Giovanna Azevedo Rodrigues, Luiz Costa et al.
Mediumship is a complex human phenomenon that can be investigated by cognitive psychiatry and consciousness neuroscience without theological assumptions or psychopathological reductionism. This study aimed to formulate and theoretically substantiate a neuroconnectomic, genetic, and psychofunctional hypothesis of mediumship as a network phenotype characterized by greater interhemispheric...
Scientific Reports
September 15, 2026
Sakshi Chauhan, Sahil Sankhyan, Kirti Tripathi et al.
Zen meditation has been widely recognized for its psychological and physiological benefits; however, the differential impacts of meditation experience on psychophysiological biomarkers remain underexplored. This study bridges a crucial gap by investigating how Zen meditation influences anxiety, sleep quality, and EEG-derived brain activity in novice and experienced meditators. Over three days,...
Psychotropes
September 15, 2026
Zoë Dubus
Durant la première vague d’études occidentales sur les propriétés thérapeutiques du LSD, l’une de ses indications principales dans le modèle « psychédélique » (administration de fortes doses en une à trois séances, surtout utilisée en Amérique du Nord) concerne le traitement de la dépendance à l’alcool. À l’inverse, en Europe, où se développait le modèle « psycholytique » (faibles doses...
Chinese medical journal
September 15, 2026
Yingjie Du, Xiangting Zhao, Quan Chen et al.
Psilocybin facilitates fear extinction in rodents, but its clinical utility is hampered by 5-hydroxytryptamine (5-HT) 2A-receptor-mediated hallucinogenic effects. This study aimed to explore whether 5-HT2A receptor is obligatory for psilocybin's fear extinction and neuroplasticity effect. Male C57BL/6J mice underwent auditory-cue fear conditioning. Ketanserin (5-HT2A/2C antagonist) or MDL100907...
Neuroimage
September 14, 2026
Luxin Fan, Xin Wen, Fa Lu et al.
Whether propofol-induced loss of consciousness (LOC) reflects a single thalamocortical transition or involves temporally dissociable local and interregional dynamics remains unclear. Using stereo-electroencephalography recordings from the anterior nucleus of the thalamus, prefrontal cortex, and temporal cortex during anesthesia induction, we quantified permutation entropy, spectral power,...
Zenodo (CERN European Organization for Nuclear Research)
September 14, 2026
Shaun Robinson
preprint
Psilocybin and related psychedelics can induce transient states of increased neural variability, context sensitivity, and plasticity-associated signaling. We hypothesize that selected companion botanicals can be composed with psilocybin to create a reproducible physiological and experiential lens, a botanical context, that biases the qualitative trajectory of the psychedelic state without...
Frontiers in Neuroscience
September 14, 2026
Daria Malich, Andrii Vasylyshyn
Testosterone exerts widespread effects on brain structure and function, yet its influence on large-scale neural networks, particularly the default mode network (DMN), remains poorly understood. The role of the DMN in self-referential processing, social cognition, and mood regulation has been demonstrated over the last decade. Neuroimaging studies suggest a link between testosterone and...