ABSTRACT The prevalence of depression, anxiety, and post-traumatic stress disorder (PTSD) has increased among healthcare providers, while the effectiveness of conventional treatments remains limited. Ketamine-assisted therapy offers a promising alternative; however, few have integrated ketamine with a group-based therapeutic modality. We report a retrospective, secondary analysis of a 12-week...
Psychedelic-assisted psychotherapy: hope and dilemmaPsychedelic-assisted psychotherapy is an emerging therapeutic approach that combines the use of psychedelics (a subclass of hallucinogenic drugs) and psychotherapy for the treatment of post-traumatic stress disorder (PTSD) and treatment-resistant depression.Compared with current treatments for depression, psychedelic-assisted psychotherapy has...
There has been a burgeoning interest in psychedelics among the public, state legislatures, psychiatrists and other clinical providers, and within the research community. Increasing numbers of studies evaluating psychedelics for depression, anxiety, posttraumatic stress disorder, and substance use disorders have been conducted or are underway. While discussing psychedelics in general, the focus...
Psychedelic therapy (PT) is an emerging paradigm with great transdiagnostic potential for treating psychiatric disorders, including depression, addiction, post-traumatic stress disorder, and potentially others. 'Classic' serotonergic psychedelics, such as psilocybin and lysergic acid diethylamide (LSD), which have a key locus of action at the 5-HT2A receptor, form the main focus of this...
Background: Early trauma predicts poor psychological and physical health. Glutamatergic synaptic processes offer one avenue for understanding this relationship, given glutamate's abundance and involvement in reward and stress sensitivity, emotion, and learning. Trauma-induced glutamatergic excitotoxicity may alter neuroplasticity and approach/avoidance tendencies, increasing risk for...
Recurring nightmares are a common symptom of various mental health conditions, including post-traumatic stress disorder (PTSD), anxiety disorders, and depression. Psychotherapeutic approaches have been used to treat recurring nightmares, but their relative effectiveness is unclear. This systematic review and meta-analysis aimed to compare the efficacy of three psychotherapeutic approaches in...
Recurrent nightmares affect up to 8% of the general population and over 50% of those with a post-traumatic stress disorder (PTSD) diagnosis [1]. Despite known associations between nightmares and negative mental health outcomes [2], little is known concerning how nightmares relate to physical health outcomes. Disruptions to sleep micro- and macro-architecture in frequent nightmare recallers [3]...
Abstract Objectives Research suggests that the quality of life of professional caregivers of individuals with intellectual disabilities and autism spectrum disorder can be enhanced through mindfulness-based training. The effects of such training have been evidenced in terms of perceived psychological stress, compassion satisfaction, compassion fatigue (i.e., burnout, secondary traumatic...
Health Sciences ReviewAugust 12, 2023Burak Okumuş, Ahmet Metin, İ. Afşin Kariper4 citations
This review is on lysergic acid diethylamide (LSD), which has a halogenic effect and is addictive. Up to now, LSD has been used for pleasure-inducing or spiritual purposes. Since it is soluble in water, it can be administered in different forms. The final decision about whether it is addictive or not is undecided. The use of LSD is extensive and is also used for treating psychiatric disorders...
Depression is a widespread issue in the United States and the leading cause of disability globally, impacting people of all ages. Although selective serotonin reuptake inhibitors (SSRIs) are commonly used for treatment, they have limited effectiveness and may take weeks to show results. There is a pressing need for fast and effective solutions for various types of depression, including chronic,...