Medical Hypotheses
July 6, 2013
Sérgio Mota-Rolim, John Fontenele Araújo
50 citations
Several lines of evidence converge to the idea that rapid eye movement sleep (REMS) is a good model to foster our understanding of psychosis. Both REMS and psychosis course with internally generated perceptions and lack of rational judgment, which is attributed to a hyperlimbic activity along with hypofrontality. Interestingly, some individuals can become aware of dreaming during REMS, a...
Nature reviews. Neuroscience
June 12, 2013
David Nutt, Leslie A. King, David E Nichols
Many psychoactive drugs are used recreationally, particularly by young people. This use and its perceived dangers have led to many different classes of drugs being banned under national laws and international conventions. Indeed, the possession of cannabis, 3,4-methylenedioxy-N-methylamphetamine (MDMA; also known as ecstasy) and psychedelics is stringently regulated. An important and...
Current Drug Abuse Reviews
June 1, 2013
Lisa Jerome, Shira Schuster, B. Yazar-Klosinski
36 citations
A wider array of treatments are needed for people with substance abuse disorders. Some psychedelic compounds have been assessed as potential substance abuse treatments with promising results. MDMA may also help treat substance abuse based on shared features with psychedelic compounds and recent reports indicating that MDMAassisted psychotherapy can reduce symptoms of PTSD. Narrative reports and...
Experimental Brain Research
June 1, 2013
Briony J. Catlow, Shijie Song, Daniel Paredes et al.
266 citations
Drugs that modulate serotonin (5-HT) synaptic concentrations impact neurogenesis and hippocampal (HPC)-dependent learning. The primary objective is to determine the extent to which psilocybin (PSOP) modulates neurogenesis and thereby affects acquisition and extinction of HPC-dependent trace fear conditioning. PSOP, the 5-HT2A agonist 25I-NBMeO and the 5-HT2A/C antagonist ketanserin were...
BMC Psychiatry
May 25, 2013
Petr Bob, Petra Selesova, Jiri Raboch et al.
Background: Somatoform dissociation is a specific form of dissociation with somatic manifestations represented in the form of 'pseudoneurological' symptoms due to disturbances or alterations of normal integrated functions of consciousness, memory or identity mainly related to trauma and other psychological stressors. With respect to the distinction between psychological and somatoform...
CNS Drugs
April 1, 2013
Jerome Sarris, Erica Mcintyre, David A Camfield
154 citations
Research in the area of herbal psychopharmacology has revealed a variety of promising medicines that may provide benefit in the treatment of general anxiety and specific anxiety disorders. However, a comprehensive review of plant-based anxiolytics has been absent to date. Thus, our aim was to provide a comprehensive narrative review of plant-based medicines that have clinical and/or preclinical...
Psycho-Oncology
February 18, 2013
Paul Jones, Megan Blunda, Gina M. Biegel et al.
During the past 30 years, there has been an increase in the incidence of cancer in adolescents. While recent studies have illustrated remarkable resilience in youth living with cancer, they can also face daunting acute and chronic adjustment struggles, cognitive and school problems, family and peer relational difficulties, depression, post-traumatic stress symptoms, and other anxiety disorders....
2013
Amanda R. Russo
Much of psychotherapy research over the past few decades has focused explicitly on outcomes and neglected examining mediators or mechanisms of change. Not surprisingly, an abundance of outcome research focuses on Acceptance and Commitment Therapy (ACT). Nevertheless, very few studies have examined ACT processes in formal mediation analyses. Three potential mediators of outcomes in ACT include...
International Journal of Clinical and Experimental Hypnosis
2013
Gordon Emmerson
Abstract Ego state therapy is based on the assumption that personality is composed of parts. When people switch from 1 state to another, they take their ego identification with them, while their levels of affect, intellect, confidence, and skill change. A vaded ego state has become overwhelmed by fear or rejection such that when it becomes executive, it interferes with normal function and...
Psychotherapy and Psychosomatics
2013
Marijke L. Swart, Annette van Schagen, Jaap Lancee et al.
98 citations
Nightmares can cause great suffering as they disturb sleep, affect daily functioning and overall well-being. They are associated with psychopathology like anxiety disorders, more specifically posttraumatic stress disorder (PTSD), psychosis, personality pathology, suicide risk, and substance abuse [1,2]. Two to five percent of the general adult population suffers from one or more nightmares a...