Este trabalho apresenta uma análise sobre a terapia psicodélica como uma possível abordagem para tratamentos psiquiátricos, visando a saúde mental, explorando suas raízes históricas, fundamentos neurobiológicos e resultados clínicos. A revisão da literatura revela que substâncias psicodélicas, como a psilocibina e o MDMA (ecstasy), demonstram um potencial terapêutico promissor para transtornos...
Tryptamines, a class of 3-aminoethyl-indoles that activate the serotonin receptor, show potential for novel mental health treatments. The FDA has granted "breakthrough therapy designation" to psilocybin and MDMA for treatment-resistant depression, major depressive disorder, and post-traumatic stress disorder, sparking global research efforts. Various clinical trials are currently investigating...
There has been an emergence in psychedelic science in recent years, in both basic and applied research. Clinical trials have shown psychedelic drugs to be exceptionally effective in treating psychiatric illnesses such as post-traumatic stress disorder (PTSD) and depression, while other research suggests they may be effective in treating a range of other indications in the future. Outside of the...
Background: Research in psychedelic medicine has focused primarily on civilian populations. Further study is needed to understand whether these treatments are effective for Veteran populations.Objectives: Here, we examine the effectiveness of psychedelic-assisted therapy among trauma-exposed Special Operations Forces Veterans (SOFV) seeking treatment for cognitive and mental health problems in...
Dissociative disorders (DDs) are characterized by a discontinuity in the normal integration of consciousness, memory, identity, emotion, perception, bodily representation, motor control, and action. The life-threatening coronavirus disease 2019 (COVID-19) pandemic has been identified as a potentially traumatic event and may produce a wide range of mental health problems, such as depression,...
This article begins by identifying and defining a range of debilitating disorders— trauma, posttraumatic stress disorder (PTSD) and generalised anxiety—and their symptoms before presenting a statistical analysis to give scope to the impact of the disorders. The article then explores the science behind breathing and breathwork as a valuable antidote to these disorders. The whakapapa of the...
ABSTRACT The prevalence of depression, anxiety, and post-traumatic stress disorder (PTSD) has increased among healthcare providers, while the effectiveness of conventional treatments remains limited. Ketamine-assisted therapy offers a promising alternative; however, few have integrated ketamine with a group-based therapeutic modality. We report a retrospective, secondary analysis of a 12-week...
Psychedelic-assisted psychotherapy: hope and dilemmaPsychedelic-assisted psychotherapy is an emerging therapeutic approach that combines the use of psychedelics (a subclass of hallucinogenic drugs) and psychotherapy for the treatment of post-traumatic stress disorder (PTSD) and treatment-resistant depression.Compared with current treatments for depression, psychedelic-assisted psychotherapy has...
There has been a burgeoning interest in psychedelics among the public, state legislatures, psychiatrists and other clinical providers, and within the research community. Increasing numbers of studies evaluating psychedelics for depression, anxiety, posttraumatic stress disorder, and substance use disorders have been conducted or are underway. While discussing psychedelics in general, the focus...
Psychedelic therapy (PT) is an emerging paradigm with great transdiagnostic potential for treating psychiatric disorders, including depression, addiction, post-traumatic stress disorder, and potentially others. 'Classic' serotonergic psychedelics, such as psilocybin and lysergic acid diethylamide (LSD), which have a key locus of action at the 5-HT2A receptor, form the main focus of this...