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PTSD: all studies

Page 110 of 211: studies 1,091 to 1,100 of 2,101, newest first. Back to the PTSD overview

Research

A community-centered approach to psychedelics.

Discover Mental Health November 27, 2025 Sean M. Viña

The renewed interest in psychedelics for mental health treatment presents both promise and complexity. Substances like psilocybin and MDMA have shown potential in addressing conditions such as PTSD and depression, particularly when administered in supportive contexts. Yet as these therapies move toward mainstream adoption, concerns arise about rapid medicalization, corporate monopolization, and...

Psychological stress and cardiovascular disease: A clinical appraisal of Sudarshan Kriya Yoga as a preventive intervention

Medicine India November 25, 2025 Shilpa Bharat Mendon

Professional associations in cardiovascular medicine do not view psychosocial distress as a risk factor for cardiovascular disease (CVD) on its own. Nonetheless, a number of experts think that assessing for psychological distress can improve the prediction of CVD risk. Persistence and commitment to complex lifestyle modifications aimed at lowering the risk of CVD are significantly influenced by...

DOI: 10.25259/medindia_32_2025 (opens in new tab) Full text (opens in new tab) Meditation Psychosocial Intervention counseling Psychological distress +10

Oral Glutamatergic Augmentation for Trauma-Related Disorders with Fluoxetine- / Bupropion- Potentiated Dextromethorphan ± Piracetam: A Four-Patient Case Series

Research Square November 25, 2025 Nai‐kong V. Cheung 1 citation preprint

Abstract Traditional monoaminergic medications often offer limited relief for the physical and cognitive symptoms of post-traumatic stress disorder (PTSD) and complex PTSD. Growing data now point to fast-acting, glutamate-based treatments that boost synaptic plasticity and interrupt fear-conditioned neural circuits. We report four sequential cases of hard-to-treat trauma-spectrum...

Qualitative insights into psilocybin and LSD experiences: Enhanced connection and emotion processing reported by Spanish-speaking survey respondents

Psychedelics November 15, 2025 Meghan DellaCrosse, Shoval Gilead, Rafael Lancelotta et al.

Serotonergic psychedelics like psilocybin and LSD have shown potential therapeutic benefits for mental health conditions, including depression, PTSD, and addiction. However, research remains limited due to regulatory barriers and a lack of diversity in study populations. Spanish-speaking individuals, despite their significant global and U.S. presence, are underrepresented in psychedelic...

DOI: 10.1016/j.psyche.2025.100004 (opens in new tab) Psilocybin Generalizability theory Thematic analysis Mental health +11

The psychedelic phenethylamine 25C-NBF, a selective 5-HT2A agonist, shows psychoplastogenic properties and rapid antidepressant effects in male rodents

Molecular Psychiatry November 14, 2025 Núria Nadal‐gratacós, Pol Puigseslloses, Laura Hernández‐guzmán et al.

Psychedelics have garnered significant interest for their therapeutic potential in mental health conditions such as depression, anxiety, and post-traumatic stress disorder. While research has primarily focused on well-studied psychedelics, phenethylamine derivatives have also gathered interest for their potential therapeutic applications. Thus, this study aims to investigate the pharmacological...

DOI: 10.1038/s41380-025-03341-1 (opens in new tab) Full text (opens in new tab) Phenethylamine Antidepressant Dopamine Reboxetine +8

MDMA como facilitador terapêutico: o impacto na reintegração de experiências traumáticas

DELOS Desarrollo Local Sostenible November 12, 2025 Maria Eduarda Mesquita Gonsalves, Beatriz Moreira Brazil, Maurício Cupello Peixoto

O Transtorno de Estresse Pós-Traumático (TEPT) é uma condição mental que pode surgir após experiências traumáticas, afetando a qualidade de vida dos indivíduos. O tratamento convencional envolve psicoterapia e farmacoterapia, contudo, nem sempre apresenta resultados satisfatórios. Nesse cenário, a psicoterapia assistida por 3,4-metilenodioximetanfetamina (MDMA) tem emergido como alternativa...

Do Contemplative Practices Promote Trauma Recovery? A Narrative Review from 2018 to 2023.

Healthcare November 7, 2025 Francesca Scafuto, Rossella Mattea Quinto, Graziella Orrù et al.

Background: Contemplative practices encompass a variety of static and dynamic practices. These practices, by fostering insights, heightened awareness, and a deeper connection to a broader framework of meaning, may play a crucial role in significantly reducing trauma-related symptoms in both young and adult populations. Methods: The current narrative literature review used Scopus and PubMed to...

DOI: 10.3390/healthcare13222825 (opens in new tab) Full text (opens in new tab) Mindfulness Contemplative practices Narrative review Trauma recovery +2

Efficacy, all-cause discontinuation, and safety of serotonergic psychedelics and MDMA to treat mental disorders: A living systematic review with meta-analysis.

European Neuropsychopharmacology November 7, 2025 Mikkel Højlund, Helin Y. Kafali, Begüm Kırmızı et al. 12 citations

Serotonergic psychedelics and 3,4-methylendioxtmethamphetamine (MDMA) are promising treatments for mental disorders with a continuously evolving evidence base. We searched Pubmed/Scopus/clinical trial registries up to 08july2025 for double-blind randomized controlled trials (RCTs) testing MDMA or serotonergic psychedelics in patients with mental disorders. Primary outcomes were change in...

DOI: 10.1016/j.euroneuro.2025.09.011 (opens in new tab) Psychedelic therapy MDMA Therapy Psychedelic medicine Entheogenic therapy +12

Mindfulness in trauma recovery: applications, insights, and future directions.

Frontiers in Psychology November 6, 2025

In recognition of the increasing scholarly and clinical attention to this concept, Frontiers in Psychology established a Mindfulness section in 2022. In this article, we briefly review the conceptualization of mindfulness and its , discuss its different facets, done in the context of the section's third anniversary. Furthermore, we , and discuss how mindfulness, both as a disposition and the...