Ian Briggs

2 papers in the library · 218 citations · publishing 1970-1974

Papers

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FURTHER STUDIES ON THE MODE OF ACTION OF PSYCHOTOMIMETIC DRUGS: ANTAGONISM OF THE EXCITATORY ACTIONS OF 5‐HYDROXYTRYPTAMINE BY METHYLATED DERIVATIVES OF TRYPTAMINE

British Journal of Pharmacology March 1, 1974 Philip Bradley, Ian Briggs 54 citations

The actions of 5‐methoxytryptamine (5‐MeOT), N,N ‐dimethyltryptamine (DMT), 5‐hydroxy‐ N,N ‐dimethyltryptamine (bufotenine, 5‐HODMT) and 5‐methoxy‐ N,N ‐dimethyltryptamine (5‐MeODMT), and their interactions with 5‐hydroxytryptamine (5‐HT), acetylcholine, (–)‐noradrenaline, and glutamate were studied by microiontophoresis on single neurones in the brain stem of rats anaesthetized with urethane...

DOI: 10.1111/j.1476-5381.1974.tb09609.x Psilocybin Serotonin Lysergic acid diethylamide Psychotomimetic +6

Antagonism of 5‐hydroxytryptamine by LSD 25 in the central nervous system: a possible neuronal basis for the actions of LSD 25

British Journal of Pharmacology October 1, 1970 R.j. Boakes, Philip Bradley, Ian Briggs et al. 164 citations

Summary 5‐Hydroxytryptamine (5‐HT), acetylcholine (ACh), noradrenaline (NA), glutamate, d , l ‐homocysteic acid (DLH), glycine and γ‐aminobutyric acid (GABA) were applied to single neurones in the brain stem of decerebrate cats by microiontophoresis. The abilities of d ‐lysergic acid diethylamide tartrate (LSD 25), methysergide maleate (UML 491) and 2‐bromo‐lysergic acid diethylamide (BOL 148)...

DOI: 10.1111/j.1476-5381.1970.tb09914.x Lysergic acid diethylamide Serotonin Psychotomimetic Glutamate receptor +5