The purpose of this study was to compare mindfulness meditation-based interventions (MMBIs) and psychedelic-assisted psychotherapies (PAP) in PTSD and examine altered-state mediators as a shared mechanism. Following PRISMA 2020 guidelines, PubMed, Web of Science, and EBSCOhost were systematically searched for randomized controlled trials (RCTs) published through January 2024. Trials reporting...
Encounters with seemingly autonomous non-human entities are among the most striking and consistently reported phenomena associated with psychedelic states, particularly those induced by N,N-dimethyltryptamine (DMT). In contemporary discourse, these encounters are frequently described through the archetype of the “machine elf,” a term popularized by ethnobotanist Terence McKenna in the late...
Pre-attentive information processing deficits are associated with poor outcomes in schizophrenia. The auditory mismatch negativity (MMN), observed when an auditory signal changes, is reduced in schizophrenia, related to glutamatergic dysfunction and is considered a response biomarker. We hypothesized that glycine, an N-methyl-d-aspartate receptor (NMDAR) coagonist, could reverse the...
Stroke not only causes physical impairment but also affects the psychological and emotional condition of patients, such as stress, anxiety, and depression. Meditation, especially mindfulness meditation and conscious breathing, has developed as a complementary therapy believed to help reduce stress levels and improve focus and quality of life. This study aims to explore the experiences of stroke...
This is a systematic review of the therapeutic value of yoga in mental health that incorporates philosophical, neuroscientific, and clinical viewpoints. It relies on research conducted between 2000 and 2024 to synthesize empirical findings in psychology, neurobiology, and psychiatry, considering how yoga is a multidimensional mind-body intervention. The review follows the history and...
Individual variability in psilocybin response is a major challenge for psychedelic-assisted therapy, with structural brain features potentially serving as predictive biomarkers. (Lewis et al. Biomedicines 8(2):34 2020) reported that rostral anterior cingulate cortex thickness predicted emotional experiences under psilocybin, suggesting cortical morphometry as a marker of psychedelic...
BACKGROUND: Naturalistic psychedelic use can result in a range of difficulties that impair social, occupational, and other important areas of functioning. Yet, the prevalence, phenomenology, and etiology of these outcomes remain poorly understood. Recent qualitative research has shown that individuals with long-term difficulties after psychedelic use sometimes attribute their challenges to...
Abstract Here, “content” is construed broadly, as everything presented to us during an experience, not the more restrictive “propositional” content. An interesting feature of visual phenomenology is that what we are aware of and not aware of is not experientially accessible. Our experience of objects can involve epiphanies, where we are unaware of the visual details that determine our seeing...
As artificial intelligence progresses promptly, issues adjoining synthetic consciousness and AI Qualia, the capacity of machines to experience subjective states, are gaining increasing ethical and philosophical importance. This student-centered study examines how university students perceive the ethical and deontological implications of such systems. A 30-item Likert-scale questionnaire was...
This chapter examines the evolving concepts of robotic personality and legal personality of artificial intelligence, exploring how conscious or semi-conscious machines may challenge traditional legal and moral boundaries. It situates the idea of AI qualia, meaning machine based subjective experience, within philosophical theories of mind and connects it to emerging frameworks of legal...