Schizophrenia Bulletin
April 10, 2026
Cherise Rosen, Liping Tong, Julia G. Lebovitz et al.
Depersonalization (DP) and derealization (DR) are phenomena involving alterations in sense of self and lifeworld. These phenomena often co-occur in psychosis, suggesting dimensional psychopathology and complex phenomenological alterations in consciousness, embodiment, and meaning-making. The primary aim of this study was to examine phenomenological associations, dynamics, and diagnostic...
Schizophrenia Bulletin
February 1, 2026
Huiying Nie, Liwei Zheng
Abstract Background In recent years, mental health problems among middle school students have shown a trend of younger age and diversification. Difficulty in emotional regulation has become a core factor affecting their academic performance and social adaptation. The research takes the improvement of middle school students’ emotional management ability as the core goal, proposes an intervention...
Schizophrenia Bulletin
January 16, 2026
Neil Thomas, Thomas Ward, Eleanor Longden et al.
A recent theme in the development of psychological interventions for hearing voices (auditory verbal hallucinations) has been the emergence of a group of overlapping approaches increasingly referred to as relational therapies: Relating Therapy (RT), Talking with Voices (TwV), and AVATAR Therapy (AT). Collaborative discussion among a group of researchers involved in developing these...
Schizophrenia Bulletin
December 14, 2025
Stjepan Curic, Moritz Haaf, Darius Zokai et al.
Pre-attentive information processing deficits are associated with poor outcomes in schizophrenia. The auditory mismatch negativity (MMN), observed when an auditory signal changes, is reduced in schizophrenia, related to glutamatergic dysfunction and is considered a response biomarker. We hypothesized that glycine, an N-methyl-d-aspartate receptor (NMDAR) coagonist, could reverse the...
Schizophrenia Bulletin
November 10, 2025
Elahe Arani, Simona Garobbio, Maya Roinishvili et al.
3 citations
Individuals with schizophrenia have less priors than controls, meaning they rely less upon their prior experiences to interpret the current stimuli. These differences in priors are expected to show as higher alternation rates in bistable perception tasks like the Structure-from-Motion (SfM) paradigm. In this paradigm, continuously moving dots in two dimensions are perceived subjectively as...
Schizophrenia Bulletin
October 6, 2025
Charles Fernyhough, Janna De Boer, Paige E Davis et al.
3 citations
Hallucinations figure prominently in a range of psychiatric disorders but, to date, their developmental origins are not well understood. The aim of the present article is to explore how ideas from mainstream developmental psychology can enhance understanding of how hallucinations develop in different modalities across the lifecourse. Hallucinations vary in their clinical significance depending...
Schizophrenia Bulletin
October 1, 2025
Bryony Sheaves, Vanessa Cropley, Peter Moseley et al.
5 citations
BACKGROUND: Sleep dysfunction shares a bidirectional relationship with hallucinatory experiences, with the strongest path from sleep dysfunction to the occurrence of hallucinatory experiences. This review aimed to identify potential mechanisms through which sleep dysfunction leads to hallucinations. STUDY DESIGN: A narrative review was conducted across 4 levels of explanation: phenomenology...
Schizophrenia Bulletin
June 17, 2025
Daphne J Holt, Rachel Sussman, Daniel Johnson et al.
1 citation
Stress sensitivity may represent an important target for resilience-promoting, preventive interventions. Resilience Training (RT) is a 4-session, group-based behavioral intervention, focusing on mindfulness-based skills, that leads to reductions in psychopathology. To investigate the mechanisms of RT, the current study tested whether acquiring the skills taught in RT leads to decreases in...
Schizophrenia Bulletin
May 25, 2025
Andrea Raballo, Mads Gram Henriksen, Michele Poletti et al.
9 citations
Self-disorders (SD) designate a pattern of non-psychotic anomalous self-experiences, which specifically aggregate in clinical and subclinical forms of schizophrenia spectrum disorders (SSD), including familial high-risk configurations. SD have been corroborated as a valuable, quantitatively tractable, trait phenotype for indexing genetic liability to SSD, and, as a risk phenotype, they offer...
Schizophrenia Bulletin
April 17, 2025
Nathan H. Heller, Frederick S. Barrett, Tobias Buchborn et al.
3 citations
Abstract Background and Hypothesis Visual hallucinations (VH) are a core symptom of both Lewy body diseases (LBDs; eg, Parkinson’s disease and dementia with Lewy bodies) and serotonergic psychedelics (SPs; eg, psilocybin and mescaline). While these conditions differ in etiology, overlapping phenomenology, and neural mechanisms suggest shared pathways. This review explores similarities and...
Schizophrenia Bulletin
February 21, 2025
Hella Janssen, K.C. van den Berg, Ger P. J. Keijsers et al.
2 citations
BACKGROUND: In psychosis spectrum disorders, maladaptive mental imagery is associated with auditory verbal hallucinations (AVHs). This study evaluates the feasibility, acceptability, and effectiveness of the following 4 imagery techniques in targeting mental imagery and AVHs severity: Imagery Rescripting (ImRs), Promoting positive Imagery de novo (Pos-Im), Metacognitive Imagery techniques...
Schizophrenia Bulletin
November 16, 2024
Inge Hahne, Marco Zierhut, Niklas Bergmann et al.
3 citations
The efficacy of yoga as an adjunctive treatment for schizophrenia spectrum disorders (SSD) has garnered interest. While yoga may positively influence various symptom domains, further investigation is needed due to the limited number, quality, and generalizability of studies. This study assessed the feasibility and acceptability (primary outcome) of a yoga-based group intervention (YoGI)...
Schizophrenia Bulletin
August 27, 2024
Bianca Bianciardi, Helena Mastek, Michelle Franka et al.
6 citations
N-Methyl-d-aspartate receptor (NMDA-R) hypofunctioning has been hypothesized to be involved in circuit dysfunctions in schizophrenia (ScZ). Yet, it remains to be determined whether the physiological changes observed following NMDA-R antagonist administration are consistent with auditory gamma-band activity in ScZ which is dependent on NMDA-R activity. This systematic review investigated the...
Schizophrenia Bulletin
June 20, 2024
Mary F. Brunette, Robert M. Roth, Christi L. Trask et al.
5 citations
BACKGROUND AND HYPOTHESIS: Up to 43% of people with schizophrenia have a lifetime cannabis use disorder (CUD). Tetrahydrocannabinol (THC) has been shown to exacerbate psychosis in a dose-dependent manner, but little research has assessed its effects on schizophrenia and co-occurring CUD (SCZ-CUD). In this double-dummy, placebo-controlled trial (total n = 130), we hypothesized that a modest dose...
Schizophrenia Bulletin
July 21, 2023
Predrag Petrović, Philipp Sterzer
42 citations
BACKGROUND AND HYPOTHESIS: The neurocomputational framework of predictive processing (PP) provides a promising approach to explaining delusions, a key symptom of psychotic disorders. According to PP, the brain makes inferences about the world by weighing prior beliefs against the available sensory data. Mismatches between prior beliefs and sensory data result in prediction errors that may...
Schizophrenia Bulletin
June 26, 2023
Anya K. Bershad, Harriet de Wit
12 citations
BACKGROUND AND HYPOTHESIS: Diminished social motivation is a negative symptom of schizophrenia and leads to severe functional consequences for many patients suffering from the illness. However, there are no effective medications available to treat this symptom. Despite the lack of approved treatments for patients, there is a growing body of literature on the effects of several classes of drugs...
Schizophrenia Bulletin
March 22, 2023
Eric J Tan, Iris E C Sommer, Lena Palaniyappan
This special issue of DISCOURSE in Psychosis focuses on the role of language in psychosis, including the relationships between formal thought disorder and conceptual disorganization, with speech and language markers and the neural mechanisms underlying these features in psychosis. It also covers the application of computational techniques in the study of language in psychosis, as well as the...
Schizophrenia Bulletin
March 15, 2023
Chi C Chan, Raquel Norel, Carla Agurto et al.
22 citations
Disturbances in self-experience are a central feature of schizophrenia and its study can enhance phenomenological understanding and inform mechanisms underlying clinical symptoms. Self-experience involves the sense of self-presence, of being the subject of one's own experiences and agent of one's own actions, and of being distinct from others. Self-experience is traditionally assessed by manual...
Schizophrenia Bulletin
February 24, 2023
Salma M Khaled, Sanne G Brederoo, Arij Yehya et al.
8 citations
While literature indicates that culture modulates phenomenological characteristics of hallucinations in schizophrenia-spectrum disorders, little is known about the extent culture modulates these characteristics in nonclinical samples. We compared lifetime prevalence, age of onset, and phenomenology of hallucinations as assessed with the Questionnaire for Psychotic Experiences between samples of...
Schizophrenia Bulletin
September 1, 2022
Peter Moseley, Adam Powell, Angela Woods et al.
15 citations
Voice-hearing in clinical and nonclinical groups has previously been compared using standardized assessments of psychotic experiences. Findings from several studies suggest that nonclinical voice-hearing is distinguished by reduced distress and increased control. However, symptom-rating scales developed for clinical populations may be limited in their ability to elucidate subtle aspects of...
Schizophrenia Bulletin
October 21, 2021
Leonie Klock, Martin Voss, Markus Weichenberger et al.
Patients with schizophrenia who experience inserted thoughts report a diminished sense of thought authorship. Based on its elusive neural basis, this functional neuroimaging study used a novel setup to convince healthy participants that a technical device triggers thoughts in their stream of consciousness. Self-reports indicate that participants experienced their thoughts as self-generated when...
Schizophrenia Bulletin
March 8, 2021
Jim van Os, L. Pries, M. Ten Have et al.
Abstract Hypotheses about the link between cannabis use and psychosis apply to the within-person level but have been tested mostly at the between-person level. We used a within-person design, in which a person serves as his own control, thus removing the need to consider confounding by any fixed (genetic and nongenetic) characteristic to study the prospective association between cannabis use...
Schizophrenia Bulletin
December 7, 2020
Ilvana Dzafic, Kit Melissa Larsen, Hayley Darke et al.
26 citations
Recent theories in computational psychiatry propose that unusual perceptual experiences and delusional beliefs may emerge as a consequence of aberrant inference and disruptions in sensory learning. The current study investigates these theories and examines the alterations that are specific to schizophrenia spectrum disorders vs those that occur as psychotic phenomena intensify, regardless of...
Schizophrenia Bulletin
August 5, 2020
Pantelis Leptourgos, Martin Fortier-Davy, Robin Carhart-Harris et al.
88 citations
Abstract The recent renaissance of psychedelic science has reignited interest in the similarity of drug-induced experiences to those more commonly observed in psychiatric contexts such as the schizophrenia-spectrum. This report from a multidisciplinary working group of the International Consortium on Hallucinations Research (ICHR) addresses this issue, putting special emphasis on hallucinatory...
Schizophrenia Bulletin
June 19, 2020
Ben Alderson-Day, Angela Woods, Peter Moseley et al.
59 citations
Recent therapeutic approaches to auditory verbal hallucinations (AVH) exploit the person-like qualities of voices. Little is known, however, about how, why, and when AVH become personified. We aimed to investigate personification in individuals' early voice-hearing experiences. We invited Early Intervention in Psychosis (EIP) service users aged 16-65 to participate in a semistructured interview...