Medical Anthropology Quarterly
December 1, 2000
E L Lewton, V Bydone
In this article, we elucidate how the Navajo synthetic principle sa'ah naagháí bik'eh hózh [symbol: see text] (SNBH) is understood, demonstrated, and elaborated in three different Navajo healing traditions. We conducted interviews with Navajo healers and their patients affiliated with Traditional Navajo religion, the Native American Church, and Pentecostal Christianity. Their narratives provide...
Medical Anthropology Quarterly
December 1, 2000
D Milne, W Howard
Diagnosis plays a central, primary role in the therapeutic process across cultures. In this article, the authors examine the role of diagnosis in two Navajo religious healing traditions, the Traditional Navajo religion and the Native American Church (NAC), and examine a case study of a diagnostic encounter between an NAC diagnostician and a Traditional patient. The authors assert that, for...
New England Journal of Medicine
May 6, 1999
Scott Mintzer, Susan L. Hickenbottom, Sid Gilman
56 citations
To the Editor: Recreational use of 3,4-methylenedioxymethamphetamine (MDMA, or “ecstasy”), a hallucinogen, has increased both in Europe and the United States.1 This substance is manufactured in illicit laboratories from a variety of organic ketone precursors. MDMA, which is structurally related both to the stimulant amphetamine and to the hallucinogen mescaline, promotes the release of both...
Pharmacopsychiatry
July 1, 1998
K.-A. Kovar
32 citations
Amphetamines, tryptamines, phencyclidines, tetrahydrocannabinol and substances of the ecstasy group are characterized as stimulants, hallucinogens and entactogens. The various effects of each group and their mode of action in different transmitter systems are described. 28 new compounds of the amphetamine and tryptamine series has been calculated, which exceed the hallucinogenic effects of...
Drug and Alcohol Dependence
June 1, 1998
Gerard J. Marek, George K. Aghajanian
39 citations
The psychedelic hallucinogens are comprised of three different groups of compounds according to Ž . Ž . their chemical structure Fig. 1 : 1 the ergolines Ž which contain an indole moiety e.g. lysergic acid . Ž . diethylamide, LSD ; 2 simple indoleamine hallucinoŽ gens e.g. N,N-dimethyltryptamine, DMT and psilocy. bin which share an indoleamine structure with the Ž endogenous neurotransmitter...
Thorax
September 1, 1996
K. Rezvani, Arvinder S Kurbaan, D. Brenton
19 citations
Two cases are reported of pneumomediastinum induced by the use of Ecstasy, a semi-synthetic hallucinogenic compound related to amphetamine and mescaline which has become established as a recreational drug in the UK since the late 1980s. Both cases recovered without incident, but it is important that the possible complications of this drug be publicised so that at risk subjects can be diagnosed...
Journal of Medicinal Chemistry
1996
Aaron Monte, Danuta Marona‐lewicka, Matthew Parker et al.
106 citations
Tetrahydrobenzodifuran functionalities were employed as conformationally restricted bioisosteres of the aromatic methoxy groups in prototypical hallucinogenic phenylalkylamines 1 and 2. Thus, a series of 8-substituted 1-(2,3,6,7-tetrahydrobenzo[1,2-b:4,5-b']difuran-4-yl)-2-aminoal kanes (7a-e) were prepared and evaluated for activity in the two-lever drug discrimination paradigm in rats trained...
Behavioural Brain Research
December 1, 1995
Rick J. Strassman
257 citations
We generated dose-response data for the endogenous and ultra-short-acting hallucinogen, N,N-dimethyltryptamine (DMT), in a cohort of experienced hallucinogen users, measuring multiple biological and psychological outcome measures. Subjective responses were quantified with a new rating scale, the HRS, which provided better resolution of dose effects than did the biological variables. A tolerance...
Behavioural Pharmacology
April 1, 1995
Lisa E Baker, Jonathan M. Broadbent, E. K. Michael et al.
52 citations
The discriminative stimulus effects of the stereoisomers of 3,4-methylenedioxymethamphetamine (MDMA) were studied in rats trained to discriminate 1.25mg/kg of (+)-MDMA or 3.5mg/kg of (-)-MDMA from saline, in a two lever, water-reinforced, drug discrimination situation. The isomers of MDMA and 3,4-methylenedioxyamphetamine (MDA) substituted completely for both training drugs. The stimulants...
Journal of American College Health
May 1, 1994
Michael J. Cuomo, Paul G. Dyment, Victoria M. Gammino
82 citations
We conducted a random survey of illicit drug use by undergraduate students at a private southern university in 1990 and compared the results with results from a similar 1986 survey of that college's student population. During the 4 years since the first study, the prevalence of cocaine use declined from 39% to 21%, and use of traditional amphetamines declined from 22% to 12%. No significant...