This study investigates the effectiveness of a 5-day intensive Mindfulness-Based Stress Reduction (MBSR) program in enhancing emotional well-being, reducing depressive symptoms, and improving mindfulness awareness. Addressing the limited evidence on condensed mindfulness formats, twelve adult participants completed validated pre- and post-intervention assessments, including the Emotional...
Amanita muscaria (L.) Lam, 1783 (Agaricales: Amanitaceae), commonly known as the fly agaric, is one of the most iconic and visually distinctive mushroom species, recognized for its striking red cap with white spots. This species has significant biological, ecological, medicinal, and ethnomycological relevance. Its bioactive compounds, mainly muscimol, ibotenic acid, and muscarine, exhibit...
JAMA Network OpenJanuary 2, 2026Gianluca Andri Florineth, Isabell Klima, Anna Laura Boeker et al.5 citations
Psychedelic-assisted therapy (PAT) is a novel intervention for depressive symptoms, typically delivered with additional psychological therapy sessions. Quantitative evidence on how this concomitant therapy contributes to treatment outcomes is limited, highlighting the need for a systematic synthesis. To evaluate whether the quantity of psychological therapy is associated with symptom reduction...
BMC PsychologyJanuary 2, 2026Reza Moshfeghinia, Sara Mostafavi, Kimia Jazi et al.2 citations
Psilocybin may reduce depressive symptoms in cancer patients, with mixed effects on anxiety and time-dependent improvements in spiritual well-being and (in single-arm data) quality of life. Given the small number of studies, high heterogeneity, challenges with blinding/expectancy, and frequent co-intervention with psychotherapy, these findings are preliminary. Larger, rigorously blinded trials...
Mild cognitive impairment (MCI) is a high-risk prodromal state for Alzheimer's disease (AD). Its progression to AD is influenced by psychological distress, stress, anxiety, and depression, and kynurenine pathway (KP) dysregulation. Mindfulness-based interventions are proven to alleviate negative emotions; however, their impact on neuroinflammatory KP is unknown. This study determined the impact...
The Assessment of Clinician's Subjective Experience (ACSE) is a self-report questionnaire developed to evaluate clinicians' subjective experiences during patient interactions. While its psychometric properties and clinical validity have been supported, its neurobiological correlates have not yet been investigated. In this pilot study, two clinicians and ten patients participated in a...
Friend and/or family caregivers (FCGs) of those with terminal cancer are heavily relied upon to address the emotional and physical needs of the patient facing death. Although increasing research has focused on testing supportive interventions for FCGs who deliver home-based care at end of life, limited attention has targeted strategies that support grief processing for bereaved FCGs during the...
To evaluate the effects of mindfulness meditation combined with eCASH-based nursing on perioperative pain and early recovery in patients with preeclampsia undergoing cesarean section. This retrospective study included 107 patients with preeclampsia who underwent cesarean section. According to the perioperative nursing intervention received, patients were assigned to a control group (n=53,...
To investigate the effects of mindfulness-based stress reduction (MBSR) combined with cardiopulmonary rehabilitation (CR) training on cardiopulmonary function, oxygen delivery efficiency, and psychological stress in patients with pulmonary arterial hypertension (PAH). A total of 50 clinically stable PAH patients were randomly assigned to an intervention group (N = 25) and a control group (N =...
2026Tiago Figueiredo, Laura Benítez, Petra Nováková
Objective: The objective of this study was to apply a causal forest machine learning algorithm to estimate the conditional average treatment effects of Mindfulness-Based Stress Reduction on pain interference and identify the specific baseline characteristics of women with chronic pain who derive the greatest therapeutic benefit. Methods and Materials: This randomized controlled trial included a...