Dementia and geriatric cognitive disorders extra

Cerebrospinal Fluid Hypocretin and Nightmares in Dementia Syndromes.

Dementia and geriatric cognitive disorders extra 2021 Lynn Marie Trotti, Donald L. Bliwise, Glenda L Keating et al.

Background/aims: Hypocretin promotes wakefulness and modulates REM sleep. Alterations in the hypocretin system are increasingly implicated in dementia. We evaluated relationships among hypocretin, dementia biomarkers, and sleep symptoms in elderly participants, most of whom had dementia. Methods: One-hundred twenty-six adults (mean age 66.2 ± 8.4 years) were recruited from the Emory Cognitive...