Novos DebatesFebruary 11, 2026Karoliny Felipe Martins
Em um contexto marcado pelo aumento do uso de drogas psiquiátricas como estratégia de enfrentamento das demandas cotidianas, observa-se maior prevalência entre mulheres, em razão dos papéis de gênero que lhes atribuem múltiplas funções em uma sociedade orientada pelo desempenho contínuo (Alvarenga; Dias, 2021). Esse cenário contribui para a medicalização progressiva de comportamentos cotidianos...
Background: Psilocybin treatment has shown promise across a range of psychiatric conditions. Mystical-type experiences during dosing sessions have been shown to predict the clinical effects of psilocybin treatment in depression, anxiety, and addiction. However, no studies have examined whether acute subjective experiences predict treatment response in obsessive-compulsive disorder (OCD)....
Mind body practices like meditation and yoga, which are widely used to support mental health, involve paying attention to internal bodily sensations like the breath. During these practices, individuals often report "interoceptive lapses," moments when attention drifts away from the body. While lapses in attention to the external world have been widely studied, far less is known about...
Abstract Ketamine is an NMDA receptor antagonist with rapid-antidepressant properties when administered at a sub-anesthetic dose. Preclinical models indicate that a direct injection of ketamine into lateral habenula (Hb), a small midbrain structure with an evolutionarily preserved role in aversive learning across mammals, can rapidly relieve depression-like behavior. However, there is limited...
Microdosing is a novel approach to the consumption of classic psychedelic substances, such as LSD (lysergic acid diethylamide) and psilocybin that emerged in recent years. Unlike traditional illicit substance use, which often seeks euphoric experiences, microdosing deliberately avoids such effects in pursuit of self-enhancement. This practice has grown in popularity likely due to the perceived...
Ayahuasca is a psychedelic plant brew that has been used in Central and South America for centuries. Recently, there has been an increase in "drug tourism" to places where ayahuasca is legally available as well as increased scientific interest in its potential mental and physical health benefits. Despite a growing body of research over the last decade, no studies to date have systematically...
Antecedentes: El dolor crónico constituye un problema de salud pública de alta prevalencia y complejidad, caracterizado por la interacción de factores biológicos, psicológicos y sociales que afectan significativamente la calidad de vida de quienes lo padecen. En las últimas décadas, diversas aproximaciones terapéuticas han incorporado enfoques basados en la aceptación y la conciencia plena,...
Purpose: Chronic Insomnia Disorder (CID) is prevalent, yet access to effective treatments is limited. Integrating mindfulness with Cognitive Behavioral Therapy for Insomnia (CBT-I) in an accessible online format may fill this gap. This study evaluated the efficacy of a therapist-guided, internet-delivered Mindfulness-Based Cognitive Therapy for Insomnia (iMBCT-I), which has been scarcely...
Frontiers in PsychologyFebruary 4, 2026Juan Camilo Benítez-Agudelo, Eduardo Navarro-Jiménez, Vicente Javier Clemente-suárez
Introduction Academic stress represents a multifactorial psychophysiological phenomenon that can disrupt emotional well-being and autonomic balance in university students. Mindfulness-based interventions (MBIs) have shown promise in enhancing emotional regulation and physiological balance. This study aimed to evaluate the autonomic and psychophysiological effects of a 13-week mindfulness-based...
Psilocin, a naturally occurring hallucinogenic component of magic mushrooms, exerts notable psychoactive effects in both humans and rodents. However, the underlying mechanisms remain not fully understood. Blood-oxygenation level-dependent (BOLD) functional magnetic resonance imaging (fMRI) is a valuable tool in many preclinical and clinical trials for investigating changes of brain activity and...