October 13, 2023
Michael Inzlicht, Taylor Bridget Sparrow-Mungal, Gregory John Depow
1 citation
preprint
Approximately 200 million people consume cannabis annually, with a significant proportion of them using it chronically. Using experience sampling, we describe the effects of chronically getting high on emotions, motivation, effort, and self-regulation in everyday life. We queried chronic users (N=260) 5 times per day over 7 days (3,701 observations) to assess immediate effects of getting high...
Journal of Medicinal Plants Research
October 9, 2023
Kodjo Eloh, Alfa Komi, Oudjaniyobi Simalou et al.
3 citations
Cannabis sativa L. is a widely used recreational drug in Togo, especially among young people. However, little is known about its chemical composition in Sub-Saharan Africa, and specifically in Togo. This study aimed to determine the levels of phytocannabinoids, specifically Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD), in cannabis samples collected from various towns in Togo using gas...
Archives of Clinical Neuropsychology
October 8, 2023
R. Hirst, Jakob Hopper, Dylan Vaughn et al.
OBJECTIVE Cannabis is one of the most widely used substances, and although the literature shows that it affects users' cognition, it is unclear how much that impact is affected by factors such as motivation. Previous studies utilizing validity measures showed that user motivation to perform well positively impacts California Verbal Learning Test - II performance, which was higher in cannabis...
Cannabis and Cannabinoid Research
October 5, 2023
Mostafa A. Elhendawy, Mohamed M. Radwan, E. Ibrahim et al.
Background: Cannabis sativa is a psychoactive plant indigenous to Central and South Asia, traditionally used both for recreational and religious purposes, in addition to folk medicine. Cannabis is a rich source of natural compounds, the most important of which are commonly known as cannabinoids that cause a variety of effects through interaction with the endocannabinoid system. Materials and...
Medical Cannabis and Cannabinoids
October 3, 2023
Mpp Amie Goodin, John Crump, D. Fadool et al.
Background: Ketamine is an anesthetic that has been proven to treat chronic pain via clinical trials; yet there is a gap in knowledge regarding the impact of the concomitant use of ketamine and cannabis on pain severity. This study examined cannabis consumers who participated in a pilot Ketamine-Assisted Psychotherapy (KAP) intervention study to examine pain severity. Methods: A subanalysis of...
bioRxiv
October 2, 2023
Roxane Verdikt, Abigail A Armstrong, Jenny Cheng et al.
preprint
Cannabis, the most consumed illicit psychoactive drug in the world, is increasingly used by pregnant women. However, while cannabinoid receptors are expressed in the early embryo, the impact of phytocannabinoids exposure on early embryonic processes is lacking. Here, we leverage a stepwise in vitro differentiation system that captures early embryonic developmental cascade to investigate the...
Pharmacology, Biochemistry, and Behavior
October 2023
Antony D Abraham, Jenny L Wiley, Julie A. Marusich
The co-use of nicotine and cannabis has been steadily rising in the United States. Rodent studies suggest that delta-9-tetrahydrocannabinol (THC) could increase addictive qualities of nicotine, but whether repeated THC exposure alters self-administration of nicotine has not been tested. We hypothesized that THC would increase the reinforcing effects of nicotine and alter nicotine intake. Adult...
Pharmacology, Biochemistry, and Behavior
October 2023
Samantha L Penman, Nicole M Roeder, Erin C. Berthold et al.
Fatty acid binding protein 5 (FABP5) interacts with the endocannabinoid system in the brain via intracellular transport of anandamide, as well as Δ9-tetrahydrocannabinol (THC), the main psychoactive component of cannabis. Previous work has established the behavioral effects of genetic deletion of FABP5, but not in the presence of THC. The present study sought to further elucidate the role of...
Revista Portuguesa de Psiquiatria e Saúde Mental
September 30, 2023
Rodrigo Saraiva, Ricardo Coentre
N/A
Neuroradiology
September 22, 2023
M. Fenzl, Martin Backens, Silviu Bodea et al.
4 citations
PURPOSE: This prospective cross-sectional study investigated the influence of regular cannabis use on brain metabolism in young cannabis users by using combined proton and phosphorus magnetic resonance spectroscopy. METHODS: The study was performed in 45 young cannabis users aged 18-30, who had been using cannabis on a regular basis over a period of at least 2 years and in 47 age-matched...