Efeito do tratamento do extrato bruto de ayahuasca em cultura de astrócitos humanos
March 16, 2026 Rebecca Rodrigues
valiosas contribuições e pela análise criteriosa deste trabalho.
Page 4 of 5: studies 61 to 80 of 85, newest first. Back to the ayahuasca overview
March 16, 2026 Rebecca Rodrigues
valiosas contribuições e pela análise criteriosa deste trabalho.
Journal of Psychoactive Drugs March 13, 2026 Matthew X. Lowe, Quinn A Darby, Sasha Kalcheff-Korn et al.
Sexual and gender minority (SGM) individuals experience disproportionately high rates of depression, anxiety, trauma, and discrimination, yet remain underrepresented in psychedelic research. This prospective, naturalistic study explored the impact of an ayahuasca retreat experience on mental health, quality of life, and spiritual well-being among SGM participants. Participants attended a...
Frontiers in Pharmacology March 11, 2026 Katrin Brache, Mauricio Diazgranados
Neuropsychiatric disorders affect nearly one billion people worldwide, yet many existing psychopharmacological treatments are limited by adverse effects, drug interactions, and variable efficacy. Ethnopharmacological knowledge embedded in Indigenous health systems offers important perspectives for understanding mental and neurological distress and for informing future research on central...
Journal of Psychopharmacology March 9, 2026 Caio César De Paula, Anna Beatriz Vicentini, Lorena Terene Lopes Guerra et al.
Ayahuasca has aroused increasing interest due to its therapeutic effects. However, its effects on cognition are poorly understood. Hence, a systematic review evaluating the cognitive effects of ayahuasca was conducted. This systematic review was conducted in accordance to Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. A comprehensive search was performed in...
Journal of Psychedelic Studies March 9, 2026 Lajos Horváth
Abstract The aim of the paper is to complement Sartre's concept of enchanted consciousness. The first section of the paper studies the contradictions inherent in Sartre's mescaline experiment and the limits of his phenomenological analysis of hallucination. The second section argues that Benny Shanon's phenomenological cognitive psychology, which is based on the typology of ayahuasca...
March 2, 2026 Rebekah Senānāyaka preprint
Rationale: Ego-dissolution represents a key therapeutic mechanism in psychedelic-assisted therapy, yet current measurement approaches may inadequately capture its multidimensional nature.Objective: To develop and validate the Multidimensional Ego-Dissolution Assessment (MEDA) and examine substance-specific patterns across classical psychedelics.Methods: Items from three validated scales...
Biomedicines February 25, 2026 Alice Melani, Giorgia Papini, Marco Bonaso et al.
In recent years, psychopharmacology has experienced a significant challenge, highlighting a renewed and strong scientific interest in psychedelics as breakthrough therapies for mental disorders. Psychedelics can influence cognitive and emotional processes, showing solid therapeutic potential, particularly in treatment-resistant psychiatric disorders. Amongst the most promising compounds,...
Current Addiction Reports February 21, 2026 Draulio B Araujo, Lucas O. Maia, Tiago Arruda Sanchez et al.
Summarizes preclinical and clinical evidence on ayahuasca—a traditional Amazonian brew combining N, N-Dimethyltryptamine (DMT) and β-carbolines—in treating depression, anxiety, post-traumatic stress disorder, substance use, eating, and personality disorders. Preclinical work shows enhanced neuroplasticity, reduced inflammation, and oxidative stress. Human neuroimaging reveals decreased default...
Translational Psychiatry February 19, 2026 Luís Carlos Pereira, Wigínio Gabriel Lira-Bandeira, Andréa Silva Medeiros-Bandeira et al.
Major depressive disorder remains a debilitating mental health disorder affecting millions worldwide, with growing prevalence among adolescents. Recent studies highlight the critical role of the somatosensory cortex in the neuropathology of depression, including structural alterations that impair cortical function. This study investigates the prophylactic effects of ayahuasca, a classic...
Frontiers in Molecular Biosciences February 18, 2026 Gabriella de Souza Gomes Ribeiro, Beatriz Aparecida Passos Bismara Paranhos, Fabiane Dörr et al. 1 citation
The findings suggest a clinically relevant interaction between ayahuasca and SSRIs, as even modest increases in DMT exposure may intensify serotonergic effects in individuals receiving antidepressant therapy. This study provides a mechanistic and quantitative framework for assessing interaction risks between ayahuasca alkaloids and SSRIs, supporting clinical decision-making and harm-reduction...
European Neuropsychopharmacology February 12, 2026 José Carlos Bouso, Óscar Andión, Sabela Fondevila Estévez et al.
The increasing interest in the therapeutic potential of psychedelics and cannabis underscores the need to understand their long-term neuropsychological and personality effects. This cross-sectional study compared regular users of ayahuasca (n = 69), cannabis (n = 56), and non-substance users (n = 94) on a battery of neuropsychological tasks and psychological questionnaires. Participants were...
REDD – Revista Espaço de Diálogo e Desconexão February 10, 2026 Julia Dias Milani
A obra Visões Multidisciplinares da Ayahuasca (2023), resultado do projeto da Cooperação Interdisciplinar para Pesquisa e Divulgação da Ayahuasca, oferece uma análise abrangente do uso da bebida em múltiplos contextos, inserindo-se no cenário contemporâneo do “renascimento psicodélico”. Organizado em três partes, o livro contempla dimensões históricas, culturais, terapêuticas, legais e...
Multimodality & Society February 9, 2026 Desiree Foerster
This article develops a new materialist approach to the representation of mystical-type experiences in Virtual Reality (VR). It investigates how sensory modalities and virtual environments are employed to translate the indeterminate and invisible qualities of mental states and evoke experiences of liminal consciousness that are characteristic of mystical-type experiences associated with...
Progress in Neuro-Psychopharmacology and Biological Psychiatry February 8, 2026 Michael J. Haupt, Savannah Pointe, Kevin F. Boehnke et al.
Ayahuasca is a psychedelic plant brew that has been used in Central and South America for centuries. Recently, there has been an increase in "drug tourism" to places where ayahuasca is legally available as well as increased scientific interest in its potential mental and physical health benefits. Despite a growing body of research over the last decade, no studies to date have systematically...
European Neuropsychopharmacology February 1, 2026 Isabel Werle, Francisco S Guimarães, Rafael G. Dos Santos et al.
Rodent studies have shown that psychedelic drugs can enhance fear extinction. However, investigations to date have relied on normative aversive conditioning procedures, which limit their relevance to trauma-related memories, as these tend to be overgeneralized and resistant to extinction. Fear extinction depends on activity and plasticity within the infralimbic (IL) region of the medial...
Social Cognitive and Affective Neuroscience January 31, 2026 Carla Soares, Gisela Lima, Marta Teixeira et al. 1 citation
Understanding the neural mechanisms underlying the impact of psychedelics on social perception and cognition may be instrumental to unravel their therapeutic potential. We conducted a pharmacoimaging study to examine ayahuasca's effects on a key theory of mind region, at the core of the third visual pathway (TVP) - the posterior superior temporal sulcus (pSTS), which is involved in facial...
Seven Editora eBooks January 19, 2026 Renato Lemes Peixoto
Este estudo investiga a história, expansão e processo de produção da Ayahuasca, uma bebida sagrada com raízes indígenas na Amazônia. Utilizando uma abordagem de revisão bibliográfica, o trabalho analisa a influência de figuras-chave e a fundação de tradições religiosas como Santo Daime e União do Vegetal. O foco principal está no detalhamento do processo de produção da Ayahuasca, que envolve a...
Revista Científica Multidisciplinaria SAPIENTIAE January 15, 2026 Rogger Silva Herrera, María Del Rosario Vivar Sarmiento
Ayahuasca, an ancestral beverage used by indigenous peoples of the Amazon, has transcended its ritual and medicinal use to become a significant resource within intercultural educational processes. This sacred brew not only represents a symbol of indigenous worldview but also acts as a bridge to integrate ancestral knowledge with contemporary educational approaches. The incorporation of...
Revista de Derecho Penal y Criminología January 13, 2026 Antonio Martín Pardo
En los últimos tiempos, la ayahuasca ha experimentado una creciente presencia en nuestras sociedades. Este fenómeno ha suscitado interrogantes en lo concerniente a su tratamiento jurídico penal. El presente artículo aborda la compleja problemática de determinar si la ayahuasca puede ser considerada en una perspectiva de lege lata objeto material de alguno de los tipos delictivos que protegen la...
Journal of the Anthropological Society of Oxford January 11, 2026 Megan Jenkins
Book review of: Alex K. Gearin. Global Ayahuasca: Wondrous Visions and Modern Worlds. Stanford University Press 2024. P. 296. ISBN: 9781503636576