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Metaphilosophy April 1, 2011 Shaun Gallagher 11 citations
Abstract: This article poses a number of questions to Richard Shusterman concerning his concepts of somaesthetics and body consciousness in his book Body Consciousness: A Philosophy of Mindfulness and Somaesthetics. How do the concepts relate to the kind of forgetfulness of the body that can happen in expert performance? What is the nature of somatic reflection, and how is it different from...
Sleep April 1, 2011 Tore Nielsen 55 citations
The author has indicated no financial conflicts of interest. Rosalind Cartwright, Professor Emeritus of Rush University Medical Center's Graduate College Neuroscience Division and founder of the first accredited Sleep Disorders and Research Center in the State of Illinois, recently published her fourth book on the topic of sleep and dreaming. She has previously written A Primer on Sleep and...
Fortschritte der Neurologie · Psychiatrie April 2011 Georgios Paslakis, P Gass, Michael Deuschle
An increasing significance has been attributed to the glutamatergic system in the pathophysiology of affective disorders. Glutamate is the most important excitatory neurotransmitter in the central nervous system. Glia cells are crucial regulators of the glutamatergic metabolism. Several studies have reported a dysfunction or reduced number of glia cells in patients suffering from depression....
Psychopharmacology April 2011 Joanne C Lin, Reem K Jan, HeeSeung Lee et al.
‘Party Pills’ containing benzylpiperazine (BZP) and trifluoromethylphenylpiperazine (TFMPP) have been used in a recreational context since the 1990s and, prior to April 2008, were legally available in New Zealand. Taken together, they have been reported to produce a ‘high’ similar to that produced by 3,4-methylenedioxymethamphetamine (MDMA). There has been little research on the subjective...
Regulatory toxicology and pharmacology : RTP April 1, 2011 Jan Van Amsterdam, Antoon Opperhuizen, Wim van den Brink 208 citations
In 2007, the Minister of Health of the Netherlands requested the CAM (Coordination point Assessment and Monitoring new drugs) to assess the overall risk of magic mushrooms. The present paper is an updated redraft of the review, written to support the assessment by CAM experts. It summarizes the literature on physical or psychological dependence, acute and chronic toxicity, risk for public...
Mitochondrion March 29, 2011 Orlagh M Kelly, Yvonne M McNamara, Lars H Manzke et al.
Previous researchers have demonstrated that 3,4-methylenedioxymethamphetamine (MDMA) induced hyperthermia, in skeletal muscle of animals, is uncoupling protein 3 (UCP3) dependent. In light of our investigations that in vivo phosphorylation of UCP1 is augmented under conditions of cold-acclimation, we set out to investigate whether (a) UCP3 was phosphorylated in vivo and (b) whether in vivo...
The Open Addiction Journal March 29, 2011 Jillian Helen Broadbear 1 citation
The Second International MDMA conference in Australasia was held at Monash University in Melbourne on July 18th-19th 2010.Research from over twenty universities was presented, in a program which included both oral papers and posters.The first Australasian MDMA conference was held earlier at the Brain Sciences Institute, Swinburne University, also in Melbourne.All attendees were active MDMA...
The Open Addiction Journal March 29, 2011 Abdallah Salem 1 citation
Project Background The main MDMA-induced adverse effect is disruption of normal thermoregulation leading to life threatening hyperthermia which is exacerbated by high ambient temperature and linked to chronic neurotoxicity. Although the focus of the majority of research on MDMAinduced loss of thermoregulation has been on brain serotonergic and dopaminergic systems, results obtained from our...
Brain Research March 25, 2011 Lívia Carla de Melo Rodrigues, Catarine Lima Conti, Ester Miyuki Nakamura-Palacios
Marijuana (Cannabis sativa) is one of the most widely used illicit drugs in the world. Its use is associated with impairments in cognitive function. We previously reported that Δ(9)-tetrahydrocannabinol (Δ(9)-THC), the primary psychoactive component of marijuana, impaired spatial working memory in the radial maze task when injected intracortically (IC) into the medial prefrontal cortex (mPFC)...
Neuroscience March 17, 2011 H Kamiyama, M Matsumoto, S Otani et al.
The non-competitive N-methyl-D-aspartate NMDA receptor antagonist ketamine, a dissociative anesthetic capable of inducing analgesia, is known to have psychotomimetic actions, but the detailed mechanisms remain unclear because of its complex properties. The present study elucidated neural mechanisms of the effect of ketamine, at doses that exert psychotomimetic effects without anesthetic and...