Page 708 of 857: studies 7,071 to 7,080 of 8,563, newest first. Back to the addiction overview
Sleep Medicine and Psychophysiology June 1, 2011 Young Min Park
Sleep-related eating disorder (SRED) is a newly recognized parasomnia that describes a clinical condition of compulsive eating under an altered level of consciousness during sleep. Recently, it is increasingly recognized in clinical practice. The exact etiology of SRED is unclear, but it is assumed that SRED might share features of both sleepwalking and eating disorder. There have been also...
The International Journal of Neuropsychopharmacology June 2011 Aurelie A Boucher, Glenn E. Hunt, Jacques Micheau et al.
Cannabis increases the risk of schizophrenia in genetically vulnerable individuals. In this study we aim to show that the schizophrenia susceptibility gene neuregulin 1 (Nrg1) modulates the development of tolerance to cannabinoids in mice. Nrg1 heterozygous (HET) and wild-type (WT) mice were treated daily for 15 d with the synthetic analogue of Δ9-tetrahydrocannabinol, CP55,940 (0.4 mg/kg). We...
Experimental Neurology June 2011 Laxmikant S Deshpande, Robert E Blair, Robert J DeLorenzo
Developing cannabinoid-based medication along with marijuana's recreational use makes it important to investigate molecular adaptations the endocannabinoid system undergoes following prolonged use and withdrawal. Repeated cannabinoid administration results in development of tolerance and produces withdrawal symptoms that may include seizures. Here we employed electrophysiological and...
Pharmacology, Biochemistry, and Behavior June 2011 Alexandre Seillier, Andrea Giuffrida
Sub-chronic administration of PCP produces a social interaction deficit that is reversed by URB597, an inhibitor of the catabolic enzyme of the endocannabinoid anandamide. Since increased anxiety may contribute to social withdrawal and URB597 has been shown to have an anxiolytic action, we studied whether this drug affected saline- and PCP-treated rats' performance in the Elevated-Plus-Maze...
British Journal of Clinical Pharmacology June 2011 Marieke Liem-Moolenaar, Peter de Boer, Maarten Timmers et al.
• The cholinergic system is important for different central nervous system functions, including memory, learning and attention. Scopolamine, a centrally active muscarinic antagonist, has been used to model dementia and to demonstrate the pharmacological effects of cholinergic drugs, but for most effects the concentration-effect relationships are unknown. • We determined the...
Pharmacology, Biochemistry, and Behavior June 2011 Ming Li, Erik He, Nick Volf
Antagonism of prepulse inhibition (PPI) deficits produced by psychotomimetic drugs has been widely used as an effective tool for the study of the mechanisms of antipsychotic action and identifying potential antipsychotic drugs. Many studies have relied on the acute effect of a single administration of antipsychotics, whereas patients with schizophrenia are treated chronically with antipsychotic...
Norwegian Archaeological Review June 1, 2011 María Cruz Berrocal 13 citations
Rock art studies have been strongly reliant on ethnography in recent decades. Since the 1970s, the (re)turn to ethnography has been considered short of a paradigmatic change, and it has indeed stirred a lot of theoretical discussion in the very under-theorized field of rock art research. The ethnographic turn has been mainly built around shamanism, very loosely defined here as the causal...
Anesthesiology June 1, 2011 Daniela Hauer, Patrizia Ratano, Maria Morena et al.
Propofol is associated with postoperative mood alterations and induces a higher incidence of dreaming compared with other general anesthetics. These effects might be mediated by propofol's inhibitory action on fatty acid amide hydrolase, the enzyme that degrades the endocannabinoid anandamide. Because propofol is also associated with a higher incidence of traumatic memories from perioperative...
Palliative & Supportive Care June 1, 2011 David K Wellisch, Marie Cohen
The purposes of this study were: (1) to explore cancer patients' complaints of poor sleep, which often involve a combination of somatic symptoms and nightmares; and (2) to understand these sleep disturbances in the light of modern dream theories and intervention modalities. The literature search originated with several major articles (Revonsuo, 2000; Krakow & Zadra, 2006; Hobson, 2009) which...
Pharmacological Reviews June 1, 2011 Christopher W Cunningham, Richard B Rothman, Thomas E Prisinzano 109 citations
Salvia divinorum is a perennial sage native to Oaxaca, Mexico, that has been used traditionally in divination rituals and as a treatment for the "semimagical" disease panzón de borrego. Because of the intense "out-of-body" experiences reported after inhalation of the pyrolized smoke, S. divinorum has been gaining popularity as a recreational hallucinogen, and the United States and several other...