Drug and Alcohol Review
September 15, 2011
Stuart A. Kinner, Jessica George, Jennifer M. Johnston et al.
19 citations
INTRODUCTION AND AIMS: A significant proportion of young Australians engage in risky alcohol consumption, and an increasing minority are regular ecstasy (3,4-methylenedioxymethamphetamine) users. Risky alcohol use, alone or in combination with ecstasy, is associated with a range of acute and chronic health risks. The aim of this study was to document the incidence and some health-related...
Drug and Alcohol Dependence
September 14, 2011
J. Grant, S. Chamberlain, Liana R. N. Schreiber et al.
Background Cannabis is the most widely used illicit substance and has been associated with cognitive impairment. It is unclear whether such impairment can occur in the absence of potential confounding influences of co-morbid axis-I disorders and use of other illicit substances. Method Young adult volunteers (18–29 years) were recruited from the general community on the basis of having no axis-I...
Human Psychopharmacology Clinical and Experimental
September 7, 2011
Philip N. Murphy, Philip G. Erwin, L. Maciver et al.
9 citations
This study aimed to examine the relationship between the consumption of ecstasy (3,4-methylenedioxymethamphetamine (MDMA)) and cannabis, and performance on the random letter generation task which generates dependent variables drawing upon executive inhibition and access to semantic long-term memory (LTM). The participant group was a between-participant independent variable with users of both...
International Journal of Yoga Therapy
September 1, 2011
Molly Lannon Kenny, Staffan Elgelid, Bidyut Bose
1 citation
By July of 2000, I was done with my job as a clinician. Having worked for over six years as a speech-language pathologist at one of the country's largest HMOs, I felt burned out, turned off, and depleted. It wasn't that I didn't like the work—I did. In fact, I loved the opportunity to come into people's lives and help them with whatever life challenges brought them to my office. What I had...
Addiction
September 1, 2011
J. Cousijn, A. Goudriaan, R. Wiers
Aims Repeated drug exposure can lead to an approach-bias, i.e. the relatively automatically triggered tendencies to approach rather that avoid drug-related stimuli. Our main aim was to study this approach-bias in heavy cannabis users with the newly developed cannabis Approach Avoidance Task (cannabis-AAT) and to investigate the predictive relationship between an approach-bias for...
Expert Opinion on Drug Safety
September 2011
Philip Robson
There is a growing consensus that cannabis dependence is a substantial and underappreciated problem. The key component responsible for the euphoric effects of cannabis and its dependence potential is δ-9-tetrahydrocannabinol (THC). THC-containing cannabinoid medicines theoretically pose a risk of abuse and dependence. In order to evaluate the potential of Sativex to cause cannabis-like...
Behavioural Pharmacology
September 2011
Alexa A Wakley, Rebecca M Craft
This study examined cannabinoid-opioid interactions within the same subjects on measures of discrimination, antinociception, horizontal locomotion, and catalepsy. Male Sprague-Dawley rats were trained to discriminate Δ(9)-tetrahydrocannabinol (THC, 3 mg/kg) from vehicle. THC alone (0.32-10 mg/kg) dose-dependently increased THC-appropriate lever responding and decreased response rate. THC alone...
Drug Testing and Analysis
September 2011
Laurent Karila, Michel Reynaud
Designer drugs belong to a group of legally or illegally produced substances that are structurally and pharmacologically very similar to illicit drugs. In the past, designer drugs were often used during all-night dance parties, but they are now consumed in multiple settings from college bars to parks to private house parties. Most of these club drugs can be bought on legal websites and...
Psychology and Aging
September 1, 2011
Brennan R. Payne, Joshua J. Jackson, S. R. Noh et al.
The current study investigated the nature of the flow state among older adults. Flow is a pleasurable experiential state that occurs during full-capacity engagement in which an individual is performing at a level that is matched with the demands of the task. Each participant completed a scale assessing dimensions of flow in a particular activity selected by the participant. More cognitively...
Pharmacopsychiatry
September 1, 2011
Simone Grimm, Milan Scheidegger, Anke Henning et al.
Ketamine is a potent glutamatergic NMDA receptor antagonist with rapid antidepressant properties, thus providing a valuable research tool for the investigation of the neurobiology of major depressive disorder (MDD). Increasing evidence underscores the role of glutamate dependent neuroplasticity and glutamatergic neurotransmission and metabolism in the pathophysiology of MDD. This multimodal...