Journal of Pharmacology and Experimental Therapeutics
August 2011
Masakuni Horiguchi, M Huang, Herbert Y. Meltzer
The role of 5-hydroxytryptamine (serotonin) (5-HT)(7) receptor antagonism in the actions of atypical antipsychotic drugs (APDs), e.g., amisulpride, clozapine, and lurasidone, if any, is uncertain. We examined the ability of 5-HT(7) receptor antagonism alone and as a component of amisulpride and lurasidone to reverse deficits in rat novel object recognition (NOR) produced by subchronic treatment...
Journal of Anesthesia
August 2011
Joon-Ho Lee, Sung-Hwan Cho, Sang-Hyun Kim et al.
We investigated the heat pain threshold (HPT) and temporal summation threshold (TST) before and after target-controlled infusion (TCI) of ketamine with an effect-site concentration (Ce) of 30 and 60 ng/ml. Healthy young volunteers (n = 20) were enrolled. A thermode was applied to the volar side of each volunteer's right forearm, and HPT and TST were measured before and after TCI of ketamine....
Anales del sistema sanitario de Navarra
August 1, 2011
Guillermo Burillo Putze, B. Prats Climent, José Luís Echarte et al.
10 citations
In recent years, a series of new drugs, known as smart drugs or legal highs, have gaining in popularity. They are easily obtainable through online shops. This is happening amongst younger segments of the population and is associated with recreational consumption, at weekends. In general, they are synthetic derivatives of natural products. There has been hardly any clinical research into them...
Infoscience (Ecole Polytechnique Fédérale de Lausanne)
August 1, 2011
Olaf Blanke, Estelle Paluelle, Christian Pfeiffer
We review recent research about human subjectivity and self-consciousness that has focused on cognitive psychology and neuroimaging of bodily self-consciousness. Multidisciplinary research on the fields of neurology, cognitive neuroscience and virtual reality opens new avenues to investigate brain mechanisms underlying a fundamental sense of the bodily self. Clinical evidence for the...
Journal of Psychopharmacology
August 2011
Susan Schenk, David N. Harper, Jennifer Do
The present study was undertaken to examine effects of self-administered MDMA on novel object exploration (NOR) memory. Self-administration was conducted during daily 2 h tests that continued until a total of 165 mg/kg was self-administered (range = 13-41 days for individual rats). Control rats were placed in the self-administration boxes during daily sessions but did not receive any drug. One...
Psychopharmacology
August 2011
Daniel L Albaugh, Jennifer A Rinker, Michael H. Baumann et al.
The abuse potential of a given drug may be mediated by both its rewarding and aversive effects, the latter of which are often far less characterized. Using the conditioned taste-aversion (CTA) preparation, the present experiments examined changes in the aversive effects of the commonly used recreational drug MDMA following repeated drug exposures. Experiment 1 used three varying doses of MDMA...
Zeitschrift für Medizinische Psychologie
August 1, 2011
Lisa Fiedler, Henrik Jungaberle, Rolf Verres
4 citations
Objectives: The Santo Daime Church is a religious community originally founded in Brazil which has increasingly attracted followers in Europe and worldwide. An important element of the religious ceremonies is the ingestion of a psychoactive substance known as ayahuasca. Ayahuasca is a psychoactive or visionary-state-inducing concoction of plants, which contains, amongst other substances,...
Oxford University Press eBooks
July 28, 2011
Bennett Hogg
25 citations
This chapter explores the connection between the idea of consciousness understood as enactive cognition and the perceptions within philosophy that ‘knowledge depends on being in a world that is inseparable from our bodies, our language, and our social history — in short, from our embodiment’. Various avatars of these three factors of our knowledge — body, language, and history — reappear over...
Frontiers in Behavioral Neuroscience
July 22, 2011
C. Zanettini, Leigh V Panlilio, M. Aliczki et al.
Cannabis has long been known to produce cognitive and emotional effects. Research has shown that cannabinoid drugs produce these effects by driving the brain’s endogenous cannabinoid system and that this system plays a modulatory role in many cognitive and emotional processes. This review focuses on the effects of endocannabinoid system modulation in animal models of cognition (learning and...
Cognitive Therapy and Research
July 13, 2011
Mindfulness is Inversely Associated with Alcohol Attentional Bias Among Recovering Alcohol-Dependent Adults.