L'Encephale
February 1, 2025
Doriane Dost, Amine Benyamina, Laurent Karila
Current scientific literature supports classical psychedelic efficacy in many psychiatric disorders. However, less attention has been given to the neurological effects of these substances. The aim of this medical thesis was to conduct a systematic review examining the neuroimaging correlates of the effects of psychedelics. We performed an electronic research through Medline and Science Direct...
L'Encephale
August 1, 2021
Lucie Berkovitch, Bruno Romeo, Laurent Karila et al.
25 citations
Psychedelics are powerful psychoactive substances. Natural psychedelics have been used for millennia by human civilizations, in particular in Latin America, while synthetic psychedelics were discovered in the 50s, giving rise to a lot of research before they were prohibited. More recently, their therapeutic properties have been studied especially to help patients with psychiatric conditions,...
Journal of Psychiatric Research
May 1, 2021
Bruno Romeo, Marianne Hermand, Amélie Pétillion et al.
74 citations
The use of psychedelic treatments has shown very promising results in some psychiatric and addictive disorders, but not all patients achieved a response. The aim of this review is to explore the clinical and biological factors which could predict the response to psychedelics in psychiatric and addictive disorders. A systematic research was performed on MEDLINE, PsycInfo, Web of science, and...
Journal of Psychopharmacology
May 25, 2020
Bruno Romeo, Laurent Karila, Catherine Martelli et al.
115 citations
Background: Psychedelic drugs have shown an efficacy in some psychiatric disorders and have an original mechanism of action with a 5-HT 2A agonism. Aim: The aim of this meta-analysis was to assess by a quantitative analysis the putative efficacy of psychedelic drugs on depressive symptoms and to investigate the kinetic of this efficacy. Methods: We searched the MEDLINE and PsycINFO databases...
Therapie
2010
Danièle Debruyne, Marie-Anne Courné, Reynald Le Boisselier et al.
Designer drugs are currently marketed as substitutes for stimulant drugs as cocaine, amphetamine, MDMA...Unlike compounds listed as narcotics, these new substances are deliberately synthesized to avoid anti-drug laws. Among them, mephedrone (4-methylmethcatinone) that belongs to cathinone family, has been recently introduced in France. Users report positive euphoric and entactogenic effects....