Serotonin is a neurotransmitter involved in many psychiatric diseases. In humans, a lack of 5-HT2B receptors is associated with serotonin-dependent phenotypes, including impulsivity and suicidality. A lack of 5-HT2B receptors in mice eliminates the effects of molecules that directly target serotonergic neurons including amphetamine derivative serotonin releasers, and selective serotonin...
The assessment of the talent of the Delphic Pythia was ambiguous among Greeks. On the one hand, they emphasized the role of Apollo in the process, saying that becoming a Pythia requires no special ability or education. On the other hand, they admitted that the Pythia infl uences the poetic quality of the oracle. Despite the modern popular view, the Delphic oracles did not require a secondary...
Phenomenology, clinical diagnostics and treatment of hallucinations Abstract. Hallucinations are perceptions without any stimulus. They occur typically in schizophrenia, but they can be found in other psychiatric or medical disorders as well. Recently, hallucinations have been increasingly reported to occur with a high prevalence in the general population and they are conceptualised as...
Anecdotal evidence indicates that supplementation with vitamin B6 (pyridoxine) before bed can enhance dream vividness and recall. In a single pilot study, Ebben, Lequerica, and Spielman (2002) found that vitamin B6 had a dose-dependent effect of increasing scores on a composite measure of dream vividness, bizarreness, emotionality, and color. The present research replicated this study using a...
This review seeks to bridge the gap between the separate but interacting mechanisms of emotion regulation and cognition, as well as their potential relationship with mindfulness meditation tools. By way of mindfulness meditation, individuals can learn how to regulate their emotions in a way that aversive stimuli will be viewed objectively; thus, the person can be free of attachment from said...
This chapter examines the philosophy of mind in relation to psychosis. It begins by re-appraising the work of Karl Jaspers. Jaspers has been taken as an apologist for biological psychiatry. However, this is ironic, as Jaspers was, as an existential philosopher, interested in the personal experience of psychosis. His account of the phenomenology of psychosis is reappraised. The philosophical...
New psychoactive substances (NPSs), i.e., newly designed substances with chemical residues that are slightly different from those of known psychoactive substances, have been emerging since the late 2000s, and social problems related to the use of these substances are increasing globally. Two such NPSs are 4-chloro-2,5-dimethoxyamphetamine (DOC), a psychedelic substance that is structurally...
Ayahuasca is a hallucinogenic beverage produced from the decoction of Banisteriopsis caapi (Bc) and Psychotria viridis (Pv), β-carboline- and N,N-dimethyltryptamine(DMT)-containing plants, respectively. Accumulating evidence suggests that ayahuasca may have therapeutic effects on ethanol abuse. It is not known, however, whether its effects are dependent on the presence of DMT or if...
This article will discuss how the ‘enactive’ approach to cognition and psychological processes can help further clarifying and developing a more heuristic framework for the understanding of severe mental disorders, in this case, depression and schizophrenia. Furthermore, enactivismwill serve as a framework that comprehends depressions and schizophrenia as disorders that encompass three...
In this report, we describe a case of a patient with substance-induced anxiety disorder occurring after a single dose of 3,4-methylenedioxymethamphetamine. Furthermore, we describe the use and efficacy of the Primary Care Behavioral Health model, a collaborative approach to integrative primary mental health care, in evaluating and treating this rare mental health disorder. Three days following...