Role of Serotonin via 5-HT2B Receptors in the Reinforcing Effects of MDMA in Mice
PLoS One November 20, 2009 Stéphane Doly, Jesus Bertran‐gonzalez, Jacques Callebert et al. 80 citations
The amphetamine derivative 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) reverses dopamine and serotonin transporters to produce efflux of dopamine and serotonin, respectively, in regions of the brain that have been implicated in reward. However, the role of serotonin/dopamine interactions in the behavioral effects of MDMA remains unclear. We previously showed that MDMA-induced locomotion,...