Early Intervention in Psychiatry
August 10, 2022
Stephanie M. Woolridge, Chelsea Wood‐Ross, Rohit Voleti et al.
5 citations
AIM: Rates of cannabis use are elevated in early psychosis populations, rendering it difficult to determine if an episode of psychosis is related to cannabis use (e.g., cannabis-induced psychosis), or if substance use is co-occurring with a primary psychotic disorder (e.g., schizophrenia). Clinical presentations of these disorders are often indistinguishable, hindering assessment and treatment....
Cognitive Neurodynamics
August 10, 2022
Sergey B. Yurchenko
The brain integrates volition, cognition, and consciousness seamlessly over three hierarchical (scale-dependent) levels of neural activity for their emergence: a causal or 'hard' level, a computational (unconscious) or 'soft' level, and a phenomenal (conscious) or 'psyche' level respectively. The cognitive evolution theory (CET) is based on three general prerequisites: physicalism, dynamism,...
Journal of Psychedelic Studies
August 8, 2022
Alexander Irvine, David Luke
27 citations
Abstract Background and Aims Little is known about individual differences in Hallucinogen Persisting Perceptual Disorder (HPPD). This study investigated visual processing style and personality across two HPPD types (HPPD I and HPPD II) and a Non-HPPD group. Methods An online survey was delivered to participants sourced from online HPPD and psychedelic user groups and forums ( N = 117). Using...
Noûs
August 4, 2022
Andrew Y. Lee
56 citations
Abstract Is a human more conscious than an octopus? In the science of consciousness, it's oftentimes assumed that some creatures (or mental states) are more conscious than others. But in recent years, a number of philosophers have argued that the notion of degrees of consciousness is conceptually confused. This paper (1) argues that the most prominent objections to degrees of consciousness are...
Cognition
August 2022
Filip Van Opstal, Molly Rooyakkers
Consciousness and high-level information integration have commonly been closely related to each other (Baars, 2002; Dehaene & Naccache, 2001; Tononi, 2004). Different results, however, have challenged this assumption by showing that information integration can occur for stimuli presented outside of conscious awareness. More recently, a re-examination of some of the data and different...
European Neuropsychopharmacology
August 2022
Xénia Gonda, Péter Döme, Berta Erdelyi-Hamza et al.
A sharp increase in the prevalence of neuropsychiatric disorders, including major depression, anxiety, substance use disorders and posttraumatic stress disorder (PTSD) has occurred due to the traumatic nature of the persisting COVID-19 global pandemic. PTSD is estimated to occur in up to 25% of individuals following exposure to acute or chronic trauma, and the pandemic has inflicted both forms...
JMIR Research Protocols
August 1, 2022
Claire Adams Spears, Josephine Mhende, China Hawkins et al.
6 citations
BACKGROUND: Tobacco use is the leading cause of preventable morbidity and mortality. Adults with low income and members of certain racial and ethnic minority groups are less likely to quit, and therefore, they experience profound tobacco-related health disparities. Mindfulness training can increase the rates of smoking cessation and lapse recovery, and telehealth and SMS text messaging have the...
Addictive Behaviors
August 2022
Adrián F Amil, Belén Rubio Ballester, Martina Maier et al.
Chronic use of cannabis leads to both motor deficits and the downregulation of CB1 receptors (CB1R) in the cerebellum. In turn, cerebellar damage is often related to impairments in motor learning and control. Further, a recent motor learning task that measures cerebellar-dependent adaptation has been shown to distinguish well between healthy subjects and chronic cannabis users. Thus, the...
Neuropharmacology
August 1, 2022
Mireia Tarrés-Gatius, Ximena López-Hill, Lluis Miquel-Rio et al.
Non-competitive NMDA receptor (NMDA-R) antagonists like ketamine, phencyclidine (PCP) and MK-801 are routinely used as pharmacological models of schizophrenia. However, the NMDA-R subtypes, neuronal types (e.g., GABA vs. glutamatergic neurons) and brain regions involved in psychotomimetic actions are not fully understood. PCP activates thalamo-cortical circuits after NMDA-R blockade in...
Journal of Palliative Medicine
August 1, 2022
William E Rosa, Zachary Sager, Megan Miller et al.
49 citations
Psychedelic-assisted therapy (PAT) is a burgeoning treatment with growing interest across a variety of settings and disciplines. Empirical evidence supports PAT as a novel therapeutic approach that provides safe and effective treatment for people suffering from a variety of diagnoses, including treatment-resistant depression, substance use disorder, and post-traumatic stress disorder. Within...