JMIR Research Protocols
August 18, 2026
Ludivine Nohales, Sandrine Touzet, Anne Termoz et al.
Abstract Background Hospital professionals face mental health challenges caused by the high demands of their work. Mindfulness meditation (MM) is a nonpharmacological practice with promising effects in promoting mental health and well-being across various hospital professionals. However, the benefits obtained from its implementation in the context of real work in hospital departments are...
JMIR Research Protocols
July 17, 2026
Santosha Veeramachaneni, Elizabeth Park, Jeffrey Martin et al.
Hypnosis is a focused state of consciousness that enhances concentration, attention, and responsiveness to suggestion. It has shown efficacy in treating psychiatric disorders such as depression, anxiety, and posttraumatic stress disorder (PTSD). However, its potential for addressing burnout and related symptoms remains underexplored. This systematic review and meta-analysis aims to assess the...
JMIR Research Protocols
July 17, 2026
Lillian Ofori Ward, Cate Bailey, Prai Wattanatakulchat et al.
In recent decades, millions of people globally have taken up Buddhist spiritual and secularized meditation practices, such as mindfulness, with the aim of improving their quality of life and well-being. Practitioners are recommended to continue meditating regularly for the long term; however, the effects of regular meditation practice after introductory instruction remain scientifically...
JMIR Research Protocols
June 12, 2026
Chelsea J Siwik, Hallie Tankha, Jacob D Hill et al.
Abstract BackgroundMigraine ranks among the leading causes of disability worldwide. Comorbid depressive symptoms are highly prevalent in patients with migraine and are associated with worsened pain severity, greater migraine-related disability, and poorer migraine prognosis. Despite this burdensome comorbidity, the treatment of these co-occurring disorders has rarely been studied. While...
JMIR Research Protocols
April 23, 2026
Kennedi Childs, Carter Minnick, Geraldine Martorella et al.
Chronic musculoskeletal pain (CMP) imposes a significant psychological, physical, and emotional burden on millions of adults in the United States. A challenge in treating CMP is its tendency to become enmeshed with a person's sense of self. Mindfulness-based interventions (MBIs) offer a promising approach to help patients disentangle pain from their sense of self. However, rigorous research is...
JMIR Research Protocols
April 20, 2026
Ruchika S Prakash, Madhura Phansikar, Megan E Fisher et al.
Abstract BackgroundIn the United States, the prevalence of Alzheimer disease (AD) is projected to double over the next 30 years, with associated familial and societal costs estimated at US $1 trillion annually if current trends continue. Although pharmacological treatments of AD are showing promise, the adoption of healthy lifestyle behaviors, particularly during the preclinical phase of AD,...
JMIR Research Protocols
August 29, 2025
Jacinda K Dariotis, Dana A Eldreth, Rachel Jackson-Gordon et al.
BackgroundChronic stress and emotional and cognitive regulation difficulties during early childhood are associated with risky behaviors and negative outcomes later in life. As preschoolers are at a developmental stage where their emotional and cognitive regulation skills are still emerging, they often rely on external support to manage their emotions and behaviors. Intervening early promotes...
JMIR Research Protocols
July 29, 2025
Nicholas Bowles, Alexander Burger, Jonathan N. Davies et al.
Mindfulness meditation has demonstrated modest benefits for mental health and well-being, although the relationship between practice dose and outcomes is unclear. Meta-analyses and randomized controlled trials have shown mixed results so far, although such results may stem from methodological issues rather than reflecting the absence of an underlying effect. Research outside structured programs...
JMIR Research Protocols
June 30, 2025
Ravi Shankar, Anjali Bundele, Amartya Mukhopadhyay
8 citations
While traditional mindfulness-based interventions demonstrate effectiveness in improving mental health outcomes, their delivery methods face significant challenges related to accessibility and engagement. Geographic barriers to trained facilitators, time constraints for in-person sessions, and participant dropout rates of 15% to 30% due to perceived monotony limit intervention reach and...
JMIR Research Protocols
May 26, 2025
Elena Nixon, Shireen Patel, Priya Patel et al.
Mindfulness-based and stress reduction interventions have been recommended by the National Institute for Health and Care Excellence guidelines in England and Wales as effective preventive mental well-being interventions for health care and other public sector staff at risk of poor mental health. This trial aims to assess the effectiveness of the increasingly implemented Mindfulness-Based...
JMIR Research Protocols
April 24, 2025
Ashley D Kendall, Emily Pela, Danielle Amonica et al.
Probation officers and other professionals who work with youth in the legal system often experience high chronic workplace stress, which can contribute over time to elevations in anxiety, depression, and workplace burnout. Emotion dysregulation appears to function as a common mechanism underlying these elevations, and growing evidence suggests it can be improved with mindfulness meditation....
JMIR Research Protocols
October 23, 2024
Gede Rasben Dantes, Nice Maylani Asril, Andrian Liem et al.
6 citations
The COVID-19 pandemic has increased the level of anxiety among Indonesian senior high school teachers, who face challenges to treat their mental disorder symptoms that arise during their working hours, as mental health services in Indonesia are limited. Therefore, it is vital to equip schoolteachers in Indonesia with early interventions that are easily available, private, and affordable, and 1...
JMIR Research Protocols
July 15, 2024
Takumu Kurosawa, Koichiro Adachi, Ryu Takizawa
6 citations
Mental health problems among workers cause enormous losses to companies in Japan. However, workers have been considered to have limited access to psychological support because of time constraints, which makes it difficult for them to engage in face-to-face psychological support interventions. This study aimed to present an intervention protocol that describes a randomized controlled trial to...
JMIR Research Protocols
June 18, 2024
Mohammad Hooshmand Zaferanieh, Lu Shi, Meenu Jindal et al.
1 citation
Depression poses a major threat to public health with an increasing prevalence in the United States. Mindfulness-based interventions, such as mindfulness-based cognitive therapy (MBCT), are effective methods for managing depression symptoms and may help fortify existing efforts to address the current disease burden. The in-person group format of MBCT, however, incurs barriers to care such as...
JMIR Research Protocols
April 17, 2024
Akash Goel, Bhavya Kapoor, Hillary Chan et al.
2 citations
Chronic pain affects approximately 8 million Canadians (~20%), impacting their physical and mental health while burdening the health care system with costs of upwards of US $60 billion a year. Indeed, patients are often trialed on numerous medications over several years without reductions to their symptoms. Therefore, there is an urgent need to identify new therapies for chronic pain to improve...
JMIR Research Protocols
February 12, 2024
Ariel Siritorn Orasud, Mai Uchiyama, Ian Pagano et al.
3 citations
Anxiety- and cancer-related neuropathy are two persistent effects related to treatment for cancer. Mindfulness meditation has been used with substantial impact as a nonpharmacologic intervention to mitigate side and late effects of treatment. Mobile apps are ubiquitous for most of the general population, yet have a particular relevance for cancer survivors, given that physical and geographic...
JMIR Research Protocols
August 28, 2023
Giovanni Ramos, Adrian Aguilera, Amanda Montoya et al.
BackgroundPeople of color (POC) who experience race-related stress are at risk of developing mental health problems, including high levels of stress, anxiety, and depression. Mindfulness meditation may be especially well suited to help POC cope, given its emphasis on gaining awareness and acceptance of emotions associated with discriminatory treatment. However, mindfulness meditation rarely...
JMIR Research Protocols
August 28, 2023
Mitsuhiro Sado, Akira Ninomiya, Maki Nagaoka et al.
BackgroundAugmented mindfulness-based cognitive therapy (MBCT) with treatment as usual (mainly pharmacotherapy) is reported to be effective after treatment for anxiety disorders. However, whether its effectiveness persists in the long term is unclear. ObjectiveThis study aims to examine the feasibility, acceptability, and effectiveness of a follow-up program by conducting a feasibility...
JMIR Research Protocols
April 28, 2023
Chad Stecher, Sara Cloonan, Sebastian Linnemayr et al.
2 citations
Chronic (ie, long-term) elevated stress is associated with a number of mental and physical health conditions. Mindfulness meditation mobile apps are a promising tool for stress self-management that can overcome several barriers associated with in-person interventions; however, to date, poor app-based intervention adherence has limited the efficacy of these mobile health tools. Anchoring, or...
JMIR Research Protocols
March 7, 2023
E. Reilly, U. Kathawalla, Hannah E Robins et al.
Background In the veteran community, chronic pain is particularly prevalent and often debilitating. Until recently, veterans with chronic pain were offered primarily pharmacological intervention options, which rarely suffice and can also have negative health consequences. To better address chronic pain in veterans, the Veterans Health Administration has invested in novel, nonpharmacological...
JMIR Research Protocols
January 27, 2023
Yuliya Knyahnytska, Reza Zomorrodi, Tyler S Kaster et al.
Suicide is among the top 10 leading causes of death worldwide. Of people who died by suicide, the majority are diagnosed with depression. It is estimated that 25%-60% of people with bipolar depression (BD) will attempt suicide at least once, and 10%-15% will die by suicide. Several treatments, such as lithium, clozapine, electroconvulsive therapy, and cognitive behavioral therapy, have been...
JMIR Research Protocols
February 22, 2021
Mitsuhiro Sado, Teppei Kosugi, Akira Ninomiya et al.
BackgroundPrevious studies have indicated that higher subjective well-being works as a protective factor for health. Some studies have already shown the effects of mindfulness-based interventions on improving subjective well-being. However, these studies targeted specific populations rather than the general public. Furthermore, they assessed either life evaluation or affective aspects of...
JMIR Research Protocols
February 22, 2021
Claudia Daudén Roquet, Corina Sas
BackgroundThe regular practice of mindfulness has been shown to provide benefits for mental well-being and prevent depression relapse. Technology-mediated interventions can facilitate the uptake and sustained practice of mindfulness, yet the evaluation of interactive systems, such as brain-computer interfaces, has been little explored. ObjectiveThe objective of this paper is to present an...
JMIR Research Protocols
June 1, 2020
S. Pizzoli, Chiara Marzorati, D. Mazzoni et al.
Background Psychophysiological stress and decreased well-being are relevant issues during prolonged social isolation periods. Relaxation practices may represent helpful exercises to cope with anxiety and stressful sensations. Objective The aim of this research protocol is to test whether remote relaxation practices such as natural sounds, deep respiration, and body scan meditation promote...
JMIR Research Protocols
2018
Elizabeth F. Ball, Sian Newton, B. Kahan et al.
Background Female chronic pelvic pain (CPP) is defined as intermittent or constant pelvic or lower abdominal pain occurring in a woman for at least 6 months. Up to a quarter of women are estimated to be affected by CPP worldwide and it is responsible for one fifth of specialist gynecological referrals in the United Kingdom. Psychological interventions are commonly utilized. As waiting times and...