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Addiction: all studies

Page 413 of 857: studies 4,121 to 4,130 of 8,563, newest first. Back to the addiction overview

Research

Towards a pluralistic neurobiological understanding of consciousness.

Trends in Cognitive Sciences May 1, 2023 Biyu J. He

Theories of consciousness are often based on the assumption that a single, unified neurobiological account will explain different types of conscious awareness. However, recent findings show that, even within a single modality such as conscious visual perception, the anatomical location, timing, and information flow of neural activity related to conscious awareness vary depending on both...

DOI: 10.1016/j.tics.2023.02.001 (opens in new tab) Full text (opens in new tab) Conscious content Conscious perception Prior knowledge State space +3

Voice phenomenology as a mirror of the past.

Psychological Medicine May 1, 2023 David Van den Berg, Eva Tolmeijer, Alyssa Jongeneel et al.

Post-traumatic mechanisms are theorised to contribute to voice-hearing in people with psychosis and a history of trauma. Phenomenological links between trauma and voices support this hypothesis, as they suggest post-traumatic processes contribute to the content of, and relationships with, voices. However, research has included small samples and lacked theory-based comprehensive assessments. In...

Great apes reach momentary altered mental states by spinning.

Primates; journal of primatology May 1, 2023 Adriano R. Lameira, Marcus Perlman 7 citations

Among animals, humans stand out in their consummate propensity to self-induce altered states of mind. Archaeology, history and ethnography show these activities have taken place since the beginnings of civilization, yet their role in the emergence and evolution of the human mind itself remains debatable. The means through which modern humans actively alter their experience of self and reality...

DOI: 10.1007/s10329-023-01056-x (opens in new tab) Full text (opens in new tab) Altered mental states Consciousness Great apes Human evolution +1

0665 Ibogaine treatment in combat Veterans significantly improves sleep, beyond alleviating Posttraumatic Stress Disorder symptoms

Sleep May 1, 2023 Afik Faerman, Lauren Anker, Kirsten Cherian et al. 5 citations

Abstract Introduction Ibogaine is an indole alkaloid traditionally used in spiritual and healing rites in some African cultures. Ibogaine is primarily studied in the context of substance dependence, but indications suggest it may enhance recovery from trauma. Here, we investigated the effects of ibogaine treatment for multisystem effects of exposure to repeated blasts and combat on...

DOI: 10.1093/sleep/zsad077.0665 (opens in new tab) Full text (opens in new tab) Insomnia Posttraumatic stress Sleep disorder Context archaeology +2

Ligand and G-protein selectivity in the κ-opioid receptor.

Nature May 1, 2023 Jianming Han, Jingying Zhang, Antonina L. Nazarova et al. 79 citations

The κ-opioid receptor (KOR) represents a highly desirable therapeutic target for treating not only pain but also addiction and affective disorders1. However, the development of KOR analgesics has been hindered by the associated hallucinogenic side effects2. The initiation of KOR signalling requires the Gi/o-family proteins including the conventional (Gi1, Gi2, Gi3, GoA and GoB) and...

DOI: 10.1038/s41586-023-06030-7 (opens in new tab) Full text (opens in new tab) Κ-opioid receptor Kor Kappa opioid receptor Receptor structure +19

A suicide attempt following psilocybin ingestion in a patient with no prior psychiatric history

Psychiatry Research Case Reports April 26, 2023 Eric N. Kramer, Kalyn Reddy, Bryan Shapiro 7 citations

Several studies have been conducted and more are underway examining psilocybin-assisted therapy as a treatment for various psychiatric conditions including depressive disorders, anxiety disorders, and alcohol use disorder. However, many studies have been limited by small sample size and have not comprehensively evaluated treatment risks outside of controlled settings. To this point, we present...

«Western psychotherapy» and «Eastern meditation» in Osho’s teaching of man’s spiritual perfection

Интеллект. Инновации. Инвестиции April 24, 2023 Yu. A. Uymina

Osho Rajneesh is one of the most controversial neo–Hinduism teachers. Like in a mirror, Osho reflected the main ideas of his time, proclaimed those principles that are desirable and relevant for modern man. Despite Osho’s widespread fame, his significance as a spiritual leader and founder of the original religious and philosophical system, the significance of his teachings and ideas in the...

Ketamine abuse: Another side of the miracle drug (A case report)

Journal of Clinical Case Reports Medical Images and Health Sciences April 21, 2023 Bouchra Hallab

Ketamine is a " dissociative anaesthetic " with fast analgesic and amnesic properties that has been used since more than 40 years. Today, ketamine abuse has become a public health concern. We report the case of a 23-year-old patient who came to the Casablanca Addictology Centre asking for help with ketamine abuse. At the interview the patient presented depressive symptoms and had already made 3...

“ISIM” DAN “ISI” DALAM PERSEMBAHAN SENI PERMAINAN KUDA KEPANG

Jurnal Pengajian Melayu April 19, 2023 Siti Islamiah Ahmad, Mohd Effindi Samsuddin, Awang Azman Awang Pawi

The art of “permainan” Kuda Kepang is a type of dance that goes through a ritual process before reaching a trance state during the performance. The current study focuses on the keywords “isim” and “isi, which refers to the form of practice taken and performed by Kuda Kepang players. This investigation focuses on the relationship between the possession of “isim” within the player and the filling...

Spatiotemporal brain complexity quantifies consciousness outside of perturbation paradigms

bioRxiv Preprint Server April 18, 2023 Martin Breyton, Jan Fousek, Giovanni Rabuffo et al. preprint

Signatures of consciousness are found in spectral and temporal properties of neuronal activity. Among these, spatiotemporal complexity after a perturbation has recently emerged as a robust metric to infer levels of consciousness. Perturbation paradigms remain, however, difficult to perform routinely. To discover alternative paradigms and metrics, we systematically explore brain stimulation and...