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Addiction: all studies

Page 401 of 855: studies 4,001 to 4,010 of 8,547, newest first. Back to the addiction overview

Research

Sustaining wakefulness: Brainstem connectivity in human consciousness

bioRxiv Preprint Server July 13, 2023 Brian L Edlow, Mark Olchanyi, Holly J Freeman et al. preprint

Consciousness is comprised of arousal (i.e., wakefulness) and awareness. Substantial progress has been made in mapping the cortical networks that modulate awareness in the human brain, but knowledge about the subcortical networks that sustain arousal is lacking. We integrated data from ex vivo diffusion MRI, immunohistochemistry, and in vivo 7 Tesla functional MRI to map the connectivity of a...

Outcomes of usage of psychedelics by people reporting an eating disorder in clinical and non-clinical settings: a scoping review

Advances in Mental Health July 13, 2023 Jorge Valdiviezo‐oña, Lizbeth Toscano-Molina, Juan Fernando Chávez et al. 4 citations

Objective To map the studies reporting the use of psychedelics in clinical and non-clinical settings by people reporting an eating disorder (ED) and their outcomes.Method To be included, peer-reviewed articles had to be written in English or Spanish and had to address the usage of psychedelics by people reporting an ED. Searches were conducted on PubMed, Scopus, and Web of Science. Data on key...

Subhallucinogenic Concentrations of Substituted Phenethylamines as a Novel Therapeutic Approach for Inflammatory and Neurological Disorders.

ACS Medicinal Chemistry Letters July 13, 2023 Robert B. Kargbo 2 citations

This Patent Highlight presents a method to treat inflammatory or neurological disorders in subjects needing treatment. The method involves administering a therapeutically effective amount of a composition containing a subhallucinogenic concentration of substituted phenethylamine. The substituted phenethylamine may belong to the 2C-X family, including 2C-H, 2C-I, 2C-B, or 2C-E. The specific...

DOI: 10.1021/acsmedchemlett.3c00220 (opens in new tab) Full text (opens in new tab) Novel therapeutics Sub-hallucinogenic dosing Phenethylamine compounds Chronic disease treatment

Psychoactive substance use in patients diagnosed with attention-deficit/hyperactivity disorder: an exploratory study

Frontiers in Psychiatry July 11, 2023 Gniewko Więckiewicz, Iga Stokłosa, Maciej Stokłosa et al. 2 citations

Introduction Attention-deficit/hyperactivity disorder (ADHD) was originally treated as a neurodevelopmental disorder that occurs mainly in children and tends to diminish or disappear with age, but we now know that symptoms persist into adulthood in over 50% of ADHD patients. Undiagnosed individuals often turn to psychoactive substance to minimize the negative aspects of functioning and improve...

DOI: 10.3389/fpsyt.2023.1184023 (opens in new tab) MDMA Ecstasy Psychoactive substance Methylphenidate +4

[Psychedelic Experiences: Phenomenology, Therapeutic Potentials and Explanatory Models].

Vertex Revista Argentina de Psiquiatría July 10, 2023 Tamara Chernoff, Bruno Kliger, Dante Hernán Venturini

Traditional psychedelics, such as LSD, psilocybin, or DMT, are psychoactive compounds that exert their effects mainly through agonism over serotonergic receptors. In appropriate doses and contexts, they produce profound changes in the subjective experience, configuring altered states of consciousness that, upon reaching a critical point, involve the appearance of phenomena of mystical,...

Mindfulness como estrategia para mejorar el desempeño académico en la educación 4.0: Estudio de caso universitario

Ciencia Nicolaita July 7, 2023 Octavio Rodriguez Sarabia

La industria 4.0 es el futuro de la humanidad, ya que con ella se ha llevado a cabo un proceso de digitalización en los sectores educativos, empresariales y urbanos, todo ello con el objetivo de ayudar a mejorar el desempeño de la ciudad para transformarla en una Smart City. Los Rankings Smart City evalúan la calidad de vida con base en factores externos, como movilidad, infraestructura y...

A predictive coding approach to psychedelic virtual-induced hallucinations and creative cognition in aging

Frontiers in Human Neuroscience July 7, 2023 Giulia Magni, Cosimo Tuena, Giuseppe Riva 9 citations

Recent research has investigated the potential of psychedelic substances in treating various neurological and psychiatric disorders. In particular, there has been a growth in studies concerning the intersection of psychedelics, Virtual Reality (VR), and Cognitive Flexibility (CF). Indeed, the use of immersive technology allows the simulation of the perceptual and cognitive effects of...

DOI: 10.3389/fnhum.2023.1219052 (opens in new tab) Cognition Creativity Executive functions Perception +2

Addressing the Current Knowledge and Gaps in Research SurroundingLysergic Acid Diethylamide (LSD), Psilocybin, and Psilocin in RodentModels

Current Topics in Medicinal Chemistry July 6, 2023 Udoka C. Ezeaka, Hye Ji J. Kim, Robert B. Laprairie 1 citation

Abstract: Lysergic acid Diethylamide (LSD), psilocybin, and psilocin are being intensively evaluated as potential therapeutics to treat depression, anxiety, substance use disorder, and a host of other psychiatric illnesses. Pre-clinical investigation of these compounds in rodent models forms a key component of their drug development process. In this review, we will summarize the evidence...

KAZAK VE KIRGIZLARDA BAKŞILIĞIN YADİGÂRI TABİPLİK

Milli Folklor July 3, 2023 Mayramgül Diykanbay, Moldir İlgi̇sheva

Physicians are the successors of Bakshis among Kazakhs and Kyrgyz and they have made themselves accepted by the society under the influence of the Islamic belief to continue their existence. They have also carried the remnants of Shamanism to the present day with its more traditional aspect. Bakshis, who call themselves physicians today, ask for help from God with their assistant jinns when...

Navigating the chaos of psychedelic fMRI brain-entropy via multi-metric evaluations of acute psilocybin effects

medRxiv July 3, 2023 Drummond E-Wen Mcculloch, Anders S. Olsen, Brice Ozenne et al. 20 citations preprint

A prominent theory of psychedelics is that they increase brain entropy. Twelve studies have evaluated psychedelic effects on fMRI brain entropy quantifications, no findings have been replicated. Here we evaluated these metrics in an independent 28-participant healthy cohort with 121 pre- and post-psilocybin fMRI scans. We assessed relations between brain entropy and plasma psilocin, brain...

DOI: 10.1101/2023.07.03.23292164 (opens in new tab) Full text (opens in new tab) Psilocybin Sample entropy Artificial intelligence Cognitive psychology +2