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Addiction: all studies

Page 390 of 857: studies 3,891 to 3,900 of 8,563, newest first. Back to the addiction overview

Research

Pharmacists and psychedelic medicine

JACCP JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY October 1, 2023 Kelan Thomas

In coming years, pharmacists will begin fielding more questions regarding psychedelic medicine, most notably with the imminent FDA approval of 3,4-methylenedioxymethamphetamine (MDMA) for posttraumatic stress disorder (PTSD) expected in 2024 and psilocybin for major depressive disorder (MDD) likely in 2025. Psychedelics are unique medications in many ways, but especially due to the mental...

Neonatal phencyclidine as a model of sex-biased schizophrenia symptomatology in adolescent mice.

Psychopharmacology October 1, 2023 Ana Carolina Dutra-Tavares, Thainá P Souza, Juliana O Silva et al.

Sex-biased differences in schizophrenia are evident in several features of the disease, including symptomatology and response to pharmacological treatments. As a neurodevelopmental disorder, these differences might originate early in life and emerge later during adolescence. Considering that the disruption of the glutamatergic system during development is known to contribute to schizophrenia,...

DOI: 10.1007/s00213-023-06434-3 (opens in new tab) Full text (opens in new tab) Cognition Neurodevelopment Postnatal phencyclidine Psychosis +2

MODULATION OF SYNAPTIC FUNCTION AND NEURONAL NETWORK ACTIVITY BY SEROTONERGIC PSYCHEDELICS

IBRO Neuroscience Reports October 1, 2023 Aneta Petrušková, Eva‐maria Weiss, Debarpan Guhathakurta et al.

Serotonergic psychedelics (SP) such as psilocybin, LSD or DMT pose significant potential for development of new strategies in treating neuropsychiatric disorders including major depression disorder, post-traumatic stress disorder and addiction. To bring these substances to clinical application, however, better understanding of the mechanisms behind their effects on many levels, including...

Magic and Its Evaluation – Reports and Views of Practitioners

Journal of Parapsychology October 1, 2023 Gerhard Mayer

This paper presents some results of a qualitative interview study with contemporary magicians that was carried out in two phases in German-speaking countries.The greater part of the data was collected in 2004-2005 and covered a broad range of topics.The topics presented here include (1) paranormal experiences of magicians, (2) evaluation of magical practice, and (3) magic in the laboratory.To...

DOI: 10.30891/jopar.2023.02.02 (opens in new tab) Full text (opens in new tab) Parapsychology Convention Association psychology Psychoanalysis +2

The Corporadelic Set and Setting

History of Pharmacy and Pharmaceuticals October 1, 2023 Ido Hartogsohn 9 citations

Abstract The term “corporadelic” signifies “manifesting corporate structures, ethos, or logic within the context of the psychedelic landscape.” It points to a relatively novel phenomena in the history of psychedelics: the appropriation of these psychoactive agents by for-profit corporations and the integration of psychedelic use into corporate setting. Set and setting is a fundamental concept...

DOI: 10.3368/hopp.65.1.131 (opens in new tab) Full text (opens in new tab) Ethos Transformational leadership Appropriation Expectancy theory +6

Identifying setting factors associated with improved ibogaine safety: a systematic review of clinical studies.

European Archives of Psychiatry and Clinical Neuroscience October 1, 2023 Juliana Mendes Rocha, José A S Reis, José Carlos Bouso et al. 21 citations

Ibogaine is a psychoactive alkaloid derived from the west-African shrub Tabernanthe iboga. Western cultures are increasing the interest for the substance due to its claimed anti addictive properties, although the evidence supporting this effect is still preliminary. The use of ibogaine often occurs with no medical supervision in uncontrolled settings, and its use has been associated with...

DOI: 10.1007/s00406-023-01590-1 (opens in new tab) Full text (opens in new tab) Noribogaine Ibogaine safety Controlled medical setting Clinical studies

Optimized infusion rates for N,N-dimethyltryptamine to achieve a target psychedelic intensity based on a modeling and simulation framework.

CPT: Pharmacometrics & Systems Pharmacology October 1, 2023 Emma Eckernäs, Jeroen Koomen, Christopher Timmermann et al. 1 citation

N,N-dimethyltryptamine (DMT) is a psychedelic compound that is being studied as a therapeutic option in various psychiatric disorders. Due to its short half-life, continuous infusion of DMT has been proposed to extend the psychedelic experience and potential therapeutic effects. The primary aim of this work was to design an infusion protocol for DMT based on a desired level of psychedelic...

DOI: 10.1002/psp4.13037 (opens in new tab) Full text (opens in new tab) Psychedelic-therapy DMT-Research Clinical-protocols Pharmacology +1

Use of Psychedelics for Pain: A Scoping Review.

Anesthesiology October 1, 2023 Akash Goel, Yeshith Rai, Shayan Sivadas et al. 29 citations

Chronic pain is a public health concern that affects approximately 1.5 billion people globally. Conventional therapeutic agents including opioid and non-opioid analgesics have been associated with adverse side effects, issues with addiction, and ineffective analgesia. Novel agents repurposed to treat pain via different mechanisms are needed to fill the therapeutic gap in chronic pain...

DOI: 10.1097/aln.0000000000004673 (opens in new tab) Full text (opens in new tab) Psychedelics Medical research Pain management Alternative medicine

Attention deficit hyperactivity disorder symptoms and lifetime use of psychoactive substances among French university students: A cross-sectional study.

Psychiatry Research October 1, 2023 François A M Jean, Ashlyn N Schwartz, Charline Galesne et al. 3 citations

In a cross sectional study of 13,837 university students, we aimed to explore the association between attention deficit hyperactivity disorder (ADHD) symptoms and lifetime psychoactive substance use (LPSU) on a wide range of illicit substances. Logistic and Hurdel multivariable regressions were used. ADHD symptoms were significantly associated with the lifetime use of ketamine, magic mushrooms,...

DISCOVERY OF AN ORIGINAL MODEL TO STUDY THE INFLUENCE OF PHARMACOLOGICALLY ACTIVE SUBSTANCES ON THE RATE OF OXYGEN CONSUMPTION IN THE PROSTATE TISSUE

Bulletin Biomedicine and sociology September 30, 2023 A.O. Lobkarev

The article provides a review of foreign scientific literature on existing approaches in scientists' ideas about the quantum theory of brain physics and the theory of quantum-like consciousness. It is shown that in recent years, physics and psychology have made important scientific advances; the emergence of new tools has led to the development of neuroscience, which makes it possible to study...