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Gabriel Riegner

4 papers in the library · 50 citations · publishing 2020-2025

Papers

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Mindfulness Meditation and Placebo Modulate Distinct Multivariate Neural Signatures to Reduce Pain.

Biological Psychiatry 2025 Gabriel Riegner, Jon G Dean, Tor D Wager et al.

Rather than a passive reflection of nociception, pain is shaped by the interplay between one's experiences, current cognitive-affective states, and expectations. The placebo response, a paradoxical yet reliable phenomenon, is postulated to reduce pain by engaging mechanisms shared with active therapies. It has been assumed that mindfulness meditation, practiced by sustaining nonjudgmental...

The role of endogenous opioids in mindfulness and sham mindfulness-meditation for the direct alleviation of evoked chronic low back pain: a randomized clinical trial.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology June 1, 2024 Lora Khatib, Jon G Dean, Valeria Oliva et al. 9 citations

Chronic low back pain (cLBP) is the most prevalent chronic pain condition. There are no treatments that haven been found to directly assuage evoked cLBP. To this extent, mindfulness-meditation is a promising pain therapy. Yet, it is unclear if meditation can be utilized to directly attenuate evoked chronic pain through endogenous opioids. A double-blind, randomized, and placebo-controlled...

Disentangling self from pain: mindfulness meditation–induced pain relief is driven by thalamic–default mode network decoupling

Pain July 7, 2022 Gabriel Riegner, Grace Posey, Valeria Oliva et al. 41 citations

ABSTRACT: For millenniums, mindfulness was believed to diminish pain by reducing the influence of self-appraisals of noxious sensations. Today, mindfulness meditation is a highly popular and effective pain therapy that is believed to engage multiple, nonplacebo-related mechanisms to attenuate pain. Recent evidence suggests that mindfulness meditation-induced pain relief is associated with the...

Neurophysiological Mechanisms Supporting Mindfulness Meditation-Based Pain Relief: an Updated Review.

Current Pain and Headache Reports August 17, 2020 Alex Jinich-Diamant, Eric L Garland, Jennifer Baumgartner et al.

This review examines recent (2016 onwards) neuroscientific findings on the mechanisms supporting mindfulness-associated pain relief. To date, its clear that mindfulness lowers pain by engaging brain processes that are distinct from placebo and vary across meditative training level. Due to rapid developments in the field of contemplative neuroscience, an update review on the neuroimaging studies...