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Journal of Interdisciplinary History of Ideas January 26, 2026 Oberto Marrama
This paper investigates how Spinoza provides a theory, consistent with his panpsychism, to account for our ability to recognize human mentality in others. It first focuses on cases that imply a failure of recognition—such as when Spinoza claims that sceptics must be regarded as “lacking a mind” (TIE.48), or when he mentions suicide victims, children, fools, and madmen as individuals whose minds...
Biology January 25, 2026 Claire A. Rice, Robert W. Stackman
Ketamine (KET) administration protocols vary widely in their design, with acute, sub-chronic, and chronic dosing regimens used to induce psychotic-like behavior in rodent models. This review compares representative classic and contemporary studies employing differing KET administration protocols to model psychosis in laboratory rodents. Specifically, we have focused on the behavioral tasks and...
bioRxiv January 24, 2026 Karen J. Tian, Brian Maniscalco, Michael L. Epstein et al. preprint
Visual experience can sometimes depart from visual performance, providing a powerful lens into the mechanisms generating conscious perception. In one proposed dissociation—subjective inflation—unattended locations in the periphery appear stronger than attended ones despite equated performance. Subjective inflation has played a central role in motivating theories of consciousness that reject the...
bioRxiv (Cold Spring Harbor Laboratory) January 23, 2026 Xiang Yan, Toru Takahashi, Yuto Kurihara et al. preprint
Abstract Mind-wandering (MW), the shift of attention away from an ongoing task, can be classified as either deliberate or spontaneous, depending on whether these internal thoughts arise intentionally or unintentionally. Previous functional magnetic resonance imaging-based resting state studies have shown that spontaneous MW traits are positively correlated with coupling within the default mode...
Brain Sciences January 23, 2026 Donatella Marazziti, Gerardo Russomanno, Matteo Gambini et al.
Background/Objectives: Sensory deprivation, defined as a reduction or absence of external sensory input across one or more modalities, has long been investigated in extreme and experimental settings. More recently, its relevance has expanded to clinical contexts and environmental conditions. The present narrative review aims to synthesize current evidence on the neurobiological mechanisms,...
Progress in Neuro-Psychopharmacology and Biological Psychiatry January 23, 2026 Bruno Romeo, Ewen Kervadec, Baptiste Fauvel et al. 1 citation
The intensity of the psychedelic experience has been shown to be associated with its clinical efficacy. This study aims to investigate the factors that may influence the level of altered consciousness during naturalistic psychedelic use, which serves as a proxy for the intensity of the psychedelic experience. A retrospective online survey was conducted on individuals who reported a psychedelic...
African journal of alcohol and drug abuse. January 22, 2026 Morris Kamenderi, John Muteti, Stephen Kimani et al.
Drugs and substance use among university students has been recognized as a global public health issue. Adolescents are particularly vulnerable to drugs and substance use (DSU) including addiction.This study sought to determine the burden of DSU among university students in Kenya. The study utilized a cross-sectional study design covering a representative sample of 17 public and private...
Neuroscience January 22, 2026 Guilherme Lodetti, Gislaine Zilli Réus, Eduardo Pacheco Rico
Pharmacotherapy for MDD is commonly prescribed to patients, yet fewer than half achieve remission. Moreover, many patients exhibit intolerant responses to pharmacological treatment, highlighting the need to explore new forms of therapy. The present work provides a narrative review of classic psychedelics as an alternative to MDD treatment. In addition, mechanisms by which psychedelics exert...
bioRxiv : the preprint server for biology January 22, 2026 Margareth Nogueira, Giuseppe Giannotti, Carley N Miller et al. preprint
Opioid use disorder remains a major health challenge worldwide. Neuronal activity in the ventral pallidum (VP) regulates opioid reward and relapse to opioid seeking but the underlying cellular mechanisms remain largely unknown. A sizable population of VP neurons previously linked to drug relapse expresses the calcium binding protein parvalbumin (VP PV ). Across the brain parvalbumin neurons are...
Langmuir January 22, 2026 Soumya Priyanshi Prusti, Raksha D. Salian, Amrita Das et al. 1 citation
The green synthesis of nanomaterials has emerged as a viable alternative to traditional techniques that reduce environmental risks and the production of harmful byproducts. In this work, biomaterial derived from wild mushrooms was used to synthesize psilocybin-derived carbon nanosheets (P-CNSs). The bioactive substance psilocybin serves as a sustainable precursor that ensures an environmentally...