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Maria Niemi

9 papers in the library · 12 citations · publishing 2021-2026

Papers

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Efficacy and Moderators of Mindfulness-Based Cognitive Therapy in Difficult-to-Treat Depression: A Systematic Review and Individual Participant Data Meta-Analysis

Psychotherapy and Psychosomatics June 12, 2026 Thorsten Barnhofer, Maria Niemi, Johannes Michalak et al. 1 citation

INTRODUCTION: Around a third of patients with major depressive disorder experience persistent symptoms despite usual treatments. Identifying scalable, psychological treatment options is critical to reduce the burden associated with difficult-to-treat depression (DTD). We examined the efficacy of mindfulness-based cognitive therapy (MBCT) compared with treatment as usual (TAU) and other active...

Negative effects of mindfulness-based cognitive therapy and cognitive behavioural analysis system of psychotherapy for patients with ‘difficult to treat’ depression: protocol for a systematic review and individual participant data meta-analysis

BMJ Open April 1, 2026 Maria Niemi, Johannes Michalak, Maria Velana et al.

Introduction Mindfulness-based interventions are widely used, yet concerns about potential negative effects—particularly those related to mindfulness meditation practice—have gained increasing attention. Individuals with difficult-to-treat depression (DTD) represent a population of particular relevance due to heightened vulnerability, but comparative evidence on clinically relevant negative...

Efficacy and moderators of mindfulness-based cognitive therapy (MBCT) in 'Difficult to Treat' depression: protocol for a systematic review and individual participant data meta-analysis of randomised controlled trials.

BMJ Open December 8, 2025 Thorsten Barnhofer, Maria Niemi, Johannes Michalak et al.

Introduction: About 30% of depressed patients suffer from a protracted course in which the disorder continues to cause significant burden despite treatment efforts. While originally developed for relapse prevention, mindfulness-based cognitive therapy (MBCT) has increasingly been investigated in depressed patients with such 'difficult-to-treat' courses. This is a protocol for an individual...

Efficacy and Moderators of Mindfulness-Based Cognitive Therapy (MBCT) in ‘Difficult to Treat’ Depression: Protocol for a Systematic Review and Individual Patient Data Meta-Analysis of Randomised Controlled Trials

medRxiv June 9, 2025 Thorsten Barnhofer, Maria Niemi, Johannes Michalak et al. preprint

ABSTRACT: Introduction: About 30% of depressed patients suffer from a protracted course in which the disorder continues to cause significant burden despite treatment efforts. While originally developed for relapse prevention, Mindfulness-Based Cognitive Therapy (MBCT) has increasingly been investigated in depressed patients with such ‘difficult-to-treat’ courses. This is a protocol for an...

Sustainable benefits of mindfulness training in health professions education.

BMC Medical Education March 27, 2025 Camilla Sköld, Anton Steen, Maria Niemi et al. 6 citations

Healthcare work and even studies towards a healthcare profession is associated with a high prevalence of distress. According to recent meta-analyses, half of the medical students worldwide suffer from burn out prior to residency, and 34% of nursing students suffer from depression. The aim of this study was to investigate healthcare students' long-term experiences of mindfulness training, and...

Mindfulness Teacher Trainees' Experiences (MTTE): An investigation of intense experiences in mindfulness-based interventions.

PLoS One 2024 Erik Jönhagen, Tim Wood, Maria Niemi et al. 5 citations

With the increasing interest in mindfulness practices within clinical as well as non-clinical settings and the increasing body of research on the positive effects of mindfulness, concerns have been raised that mindfulness might also produce adverse effects including intense experiences and psychosis. The aim of this study was to investigate if intense experiences occur as a natural part of...

The Implementation of Mindfulness-Based Programs in the Swedish Healthcare System - A Survey Study of Service Providers.

Global Advances in Health and Medicine 2021 Maria Niemi, Rebecca S. Crane, Jermo Sinselmeijer et al.

The burden of depression and anxiety is on the rise globally. Mindfulness-Based Programs (MBPs) are a particular group of psychosocial programs targeting depression and anxiety. There is growing research and practice interest in MBPs internationally, and they are becoming more commonly implemented in a number of countries' healthcare services. To systematically map the existing provision of...

The Implementation of Mindfulness-Based Programs in the Swedish Healthcare System-A Qualitative Study.

Global Advances in Health and Medicine 2021 Susanne Andermo, Rebecca S. Crane, Maria Niemi

As the provision of Mindfulness-Based Programs (MBPs) in health care settings progresses, more research is needed to develop guidelines and structures for implementation in various contexts. This study is part of a larger project were MBP provision in Sweden is explored. The objective is to provide knowledge for the next steps of MBP implementation both in Sweden and internationally. The...

DOI: 10.1177/21649561211058698 (opens in new tab) Full text (opens in new tab) Fidelity Implementation Intervention integrity Mindfulness-based programs +1

An individual patient data (IPD) meta-analysis on negative effects of Mindfulness-Based Cognitive Therapy (MBCT) and Cognitive Behavior Analysis of Psychotherapy (CBASP) for patients with difficult-to-treat depression (DTD)

Johannes Michalak, Maria Niemi, Maria Velana et al. preprint

ABSTRACT Background Chronic and treatment-resistant depression remains a challenge. Although research has demonstrated positive effects of Mindfulness-Based Cognitive Therapy (MBCT) and Cognitive Behavioral Analysis System of Psychotherapy (CBASP), their potential negative effects—including deterioration, suicidality, and adverse events—are not well understood. Objectives This protocol outlines...