50 papers in the library · 578 citations · publishing 2014-2026
Pain Medicine September 22, 2026 Steven D. Pratscher, Lloyd Lalande, Mark A. Lumley et al.
Steven D Pratscher, PhD, Lloyd Lalande, PhD, Mark A Lumley, PhD, Irene M Estores, MD, Adam W Hanley, PhD, Kimberly T Sibille, PhD, Roger B Fillingim, PhD;
International Journal of Behavioral Medicine June 12, 2026 Carter Minnick, Adam W. Hanley, Eric L Garland
BACKGROUND: Spanish-speaking individuals in the U.S. face a number of barriers to quality pain care and limited access to culturally adapted treatments. While mindfulness-based interventions are effective for chronic pain, few have been translated for Spanish-speaking populations. This pilot study tested a brief, Spanish-language adaptation of Mindfulness-Oriented Recovery Enhancement (Spanish...
Psychology of Consciousness Theory Research and Practice May 11, 2026 Kush V. Bhatt, Adam W. Hanley, Chantal Martin-Soelch et al.
Mindfulness-based interventions are efficacious nonpharmacologic treatments for chronic pain, yet the psychological mechanisms mediating the pain-relieving effects of mindfulness-based interventions remain incompletely understood. One potential mechanism may involve nondual awareness, a state of consciousness characterized by attenuation of the subject-object duality, reduced self-referential...
Journal of Integrative and Complementary Medicine May 1, 2026 Steven D. Pratscher, Lloyd Lalande, Allison Davis et al.
Chronic pain is a major public health problem. Due to the persistent, costly, and complex nature of chronic pain, there is a need for new safe and effective treatments. Integrative breathwork interventions, or therapeutic styles of conscious breathing, have promise as novel treatments for chronic pain. The primary objective of this proof-of-concept study was to examine the feasibility,...
JMIR Research Protocols April 23, 2026 Kennedi Childs, Carter Minnick, Geraldine Martorella et al.
Chronic musculoskeletal pain (CMP) imposes a significant psychological, physical, and emotional burden on millions of adults in the United States. A challenge in treating CMP is its tendency to become enmeshed with a person's sense of self. Mindfulness-based interventions (MBIs) offer a promising approach to help patients disentangle pain from their sense of self. However, rigorous research is...
Journal of Pain and Symptom Management January 3, 2026 Karolina L Bryl, Adam W. Hanley, Raymond E Baser et al. 1 citation
Chronic pain affects many cancer survivors yet remains underdiagnosed and inadequately managed. Existing treatments (e.g., opioids, NSAIDs) carry risks like addiction and limited long-term relief, while non-pharmacological options show modest effectiveness. Given these limitations innovative, evidence-based interventions are needed. Mindfulness-Oriented Recovery Enhancement (MORE), a multimodal...
Complementary Therapies in Medicine December 1, 2025 Adam W. Hanley, Yoshio Nakamura, Robert R Edwards et al.
Knee osteoarthritis (KOA) is a prevalent chronic pain condition that significantly impairs quality of life and is often treated with interventions that carry risks or provide limited relief. Reiki, a non-invasive complementary therapy, has shown early promise for pain management but lacks rigorous evaluation among American adults with KOA. This study evaluated the specific efficacy of Reiki and...
European Journal of Investigation in Health, Psychology and Education November 25, 2025 Sean D Young, Adam W. Hanley
Objectives: Chronic musculoskeletal pain (CMP) is the leading cause of years lived with disability worldwide and the costliest health condition in the United States. Mindfulness is an effective treatment for CMP, but traditional mindfulness-based interventions (MBIs) are inaccessible for many CMP patients for both format and content reasons. An MBI that leverages music may be a more accessible...
Psychological Services July 21, 2025 Tracy Herrmann, Joanna Ellen Bettmann, Adam W. Hanley et al. 1 citation
Veterans' reluctance to engage in mental health treatment coupled with high attrition in such treatment should motivate practitioners and researchers to create innovative ways to treat veterans. Nature-based interventions show promise as a means for addressing veterans' mental health needs. The present study aimed to test the feasibility and acceptability of a manualized nature-based...
Cureus March 1, 2025 Sean D Young, Josh Kim, Adam W. Hanley 1 citation
A mindfulness-based intervention (MBI) focused on listening to music might reduce chronic pain and provide a new approach to overcoming challenges from traditional MBIs (e.g., breathing). Due to the potential unpredictability and unfamiliarity of jazz, an MBI focused on listening to improvisational jazz music might be a particularly efficacious pain reduction intervention. This pilot study...
International Journal of Wellbeing October 1, 2024 Michael Dambrun, Adam W. Hanley, Eric L Garland et al. 5 citations
In two randomized controlled trials, we tested the effect of two attentional mindfulness meditation practices on positive mental health. We hypothesized that attentional meditation would increase various positive emotions (gratitude, interest, hope, pride, elevation, and awe) via three processes induced by mindfulness (body awareness, meta-awareness, and self-transcendence) and that positive...
Journal of Integrative and Complementary Medicine September 1, 2024 Adam W. Hanley, Ayaka Lingard, Eric L Garland 7 citations
Introduction: Traditional, 8-week, mindfulness-based interventions can effectively treat chronic pain, but require a time and resource investment too burdensome for many patients and providers. The solution to this logistical challenge may be to distill the core, therapeutic elements of an efficacious 8-week, mindfulness-based intervention, Mindfulness-Oriented Recovery Enhancement (MORE), into...
The American Surgeon™ May 2024 R Lynae Roberts, Adam W. Hanley, Eric L Garland
Surgical procedures often improve health and function but can sometimes also result in iatrogenic effects, including chronic pain and opioid misuse. Due to the known risks of opioids and the physical, emotional, and financial suffering that often accompanies chronic pain, there has been a call for greater use of complementary non-pharmacological treatments like mindfulness-based interventions....
JAMA Psychiatry April 1, 2024 Nina A Cooperman, Shou-En Lu, Adam W. Hanley et al. 39 citations
Methadone treatment (MT) fails to address the emotion dysregulation, pain, and reward processing deficits that often drive opioid use disorder (OUD). New interventions are needed to address these factors. To evaluate the efficacy of MT as usual (usual care) vs telehealth Mindfulness-Oriented Recovery Enhancement (MORE) plus usual care among people with an OUD and pain. This study was a...
American Journal of Psychiatry January 10, 2024 Eric L Garland, Yoshio Nakamura, Craig J. Bryan et al.
OBJECTIVE. Evaluate the efficacy of Mindfulness-Oriented Recovery Enhancement (MORE) for past and current military personnel prescribed long-term opioid therapy (LTOT) for chronic pain. METHODS. In a clinical trial, 230 past and current U.S. military personnel prescribed LTOT were randomized (1:1) to MORE or supportive psychotherapy (in-person and then online via Zoom after onset of COVID-19)....
Pain Medicine August 1, 2023 Julie M Fritz, Daniel I Rhon, Eric L Garland et al.
Background: Improving pain management for persons with chronic low back pain (LBP) undergoing surgery is an important consideration in improving patient-centered outcomes and reducing the risk of persistent opioid use after surgery. Nonpharmacological treatments, including physical therapy and mindfulness, are beneficial for nonsurgical LBP through complementary biopsychosocial mechanisms, but...
Mindfulness May 24, 2023 E. Garland, Bhanuteja Gullapalli, Kort C. Prince et al.
The opioid crisis in the USA remains severe during the COVID-19 pandemic, which has reduced access to evidence-based interventions. This Stage 1 randomized controlled trial (RCT) assessed the preliminary efficacy of Zoom-based Mindfulness-Oriented Recovery Enhancement (MORE) plus Just-in-Time Adaptive Intervention (JITAI) prompts to practice mindfulness triggered by wearable sensors (MORE +...
Psychological Medicine April 1, 2023 Eric L Garland, Spencer T Fix, Justin Hudak et al. 51 citations
Neuropsychopharmacologic effects of long-term opioid therapy (LTOT) in the context of chronic pain may result in subjective anhedonia coupled with decreased attention to natural rewards. Yet, there are no known efficacious treatments for anhedonia and reward deficits associated with chronic opioid use. Mindfulness-Oriented Recovery Enhancement (MORE), a novel behavioral intervention combining...
Cureus February 16, 2023 Dominic Arjuna B Ugarte, Adam W. Hanley, Jeffery A. Dusek et al.
Background Pain among young adult patients with sickle cell disease (PWSCD) is a highly significant public health problem associated with reduced quality of life. Due to issues uniquely affecting PWSCD, including distrust of research, challenging life situations, debilitating pain, stigma, and logistical challenges (e.g., child or elder care and transportation), SCD researchers often find it...
Mindfulness 2023 Eric L Garland, R Lynae Roberts, Adam W. Hanley et al. 14 citations
Mindfulness is theorized to decrease the affective amplification of chronic pain by facilitating a shift from emotionally-laden, catastrophic pain appraisals of nociceptive input to reappraising chronic pain as an innocuous sensory signal that does not signify harm. Understanding of these hypothetical psychological mechanisms of mindfulness-based analgesia has been limited by a lack of direct...
Science Advances October 14, 2022 Eric L Garland, Adam W. Hanley, Justin Hudak et al. 39 citations
Self-regulation is instantiated by theta oscillations (4 to 8 Hz) in neurons of frontal midline brain regions. Frontal midline theta (FMΘ) is inversely associated with default mode network (DMN) activation, which subserves self-referential processing. Addiction involves impaired self-regulation and DMN dysfunction. Mindfulness is an efficacious self-regulatory practice for treating addiction,...
Mindfulness September 15, 2022 Anna Parisi, R Lynae Roberts, Adam W. Hanley et al.
Objectives: Mindfulness-Oriented Recovery Enhancement (MORE) is an integrative intervention designed to ameliorate addiction, chronic pain, and psychiatric symptoms. Although multiple randomized controlled trials (RCTs) have examined the clinical efficacy of MORE, no study has quantitatively synthesized this body of research. Thus, we conducted a meta-analysis of RCTs examining the effects of...
JAMA Internal Medicine February 28, 2022 E. Garland, Adam W. Hanley, Yoshio Nakamura et al.
Key Points Question Does a mindfulness-based intervention reduce comorbid chronic pain and opioid misuse in the primary care setting more than supportive psychotherapy? Findings In this randomized clinical trial that included 250 adults with both chronic pain and opioid misuse, 45.0% of participants receiving Mindfulness-Oriented Recovery Enhancement (MORE) were no longer misusing opioids after...
Behaviour Research and Therapy February 28, 2022 Anna Parisi, Adam W. Hanley, E. Garland
Mindfulness-Oriented Recovery Enhancement (MORE) is an integrative treatment that simultaneously addresses chronic pain and opioid misuse. MORE has been found to produce sustained reductions in opioid craving, pain, and negative affect-key risk mechanisms precipitating opioid misuse for patients on long-term opioid therapy (LTOT). However, less is known about MORE's impact on state measures of...
JMIR Research Protocols August 30, 2021 Geraldine Martorella, Adam W. Hanley, Scott M. Pickett et al.
Cardiac surgery is a frequently performed procedure. However, pain after cardiac surgery may become chronic (lasting >3 months) in adults. Once discharged from the hospital, patients are at greater risk of developing chronic postsurgical pain (CPSP) and of prolonged opioid use, as they need to self-manage their pain. Psychological risk and protective factors such as pain-related catastrophic...