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Carol M. Greco

27 papers in the library · 1,474 citations · publishing 2007-2026

Papers

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Mindfulness-Based Group Medical Visits for Persons With Chronic Low Back Pain: A Randomized Clinical Trial.

JAMA Internal Medicine June 29, 2026 Natalia E. Morone, Keturah R Faurot, Janice M Weinberg et al.

Importance: Back pain is among the most common, disabling, and costly conditions managed in primary care in the US, but current treatment options often do not provide adequate relief. Mindfulness-based interventions have demonstrated effectiveness in individuals with chronic low back pain (CLBP); however, mindfulness remains underused in part because it is not integrated into most outpatient...

DOI: 10.1001/jamainternmed.2026.2186 (opens in new tab) Mindfulness Humans Low back pain Pain measurement +8

Mindfulness Group Visits for Chronic Low Back Pain in Primary Care: The OPTIMUM Pragmatic Clinical Trial

Innovation in Aging December 1, 2025 Natalia E. Morone, Tra Nguyen, Keturah R Faurot et al.

Abstract Mindfulness is recommended as a first-line non-pharmacologic treatment for chronic low back pain (cLBP). However, accessibility is challenging. The OPTIMUM trial (Optimizing Pain Treatment In Medical settings Using Mindfulness) compared a telehealth-delivered group mindfulness program for primary care patients with cLBP to usual care. Here we describe the methods of this investigation,...

Mindfulness-based stress reduction and loneliness in older adults: two randomized controlled trials.

The journals of gerontology. Series B, Psychological sciences and social sciences November 5, 2025 Janine M. Dutcher, Kirk W Brown, Emily K. Lindsay et al.

Loneliness is one of the most robust risk factors for morbidity and accelerated mortality among older adults, and effective interventions are needed. However, interventions to reduce loneliness have shown limited success, especially in this population. Indeed, research suggests that simply increasing social contact might not combat loneliness; instead, addressing the cognitive and emotional...

DOI: 10.1093/geronb/gbaf178 (opens in new tab) Full text (opens in new tab) Psychological interventions Social isolation Well-being

The Hidden Complexity of Virtual Mindfulness-Based Group Medical Visits: Comfort, Challenge, and the Influence of Social Determinants of Health.

Global Advances in Integrative Medicine and Health 2025 Jessica L Barnhill, Gabriela Castro, Christine Lathren et al.

Chronic low back pain is globally prevalent and associated with significant impairment in quality of life. Furthermore, people from historically marginalized communities are less likely to receive treatment, contributing to health inequities. Group mindfulness-based interventions improve pain and function, and virtual delivery has been demonstrated to be feasible. Little is known about how...

DOI: 10.1177/27536130251326938 (opens in new tab) Full text (opens in new tab) Mindfulness-baseed stress reduction Pain Telemedicine Virtual +1

A Brief Measure of Fidelity for Mindfulness Programs: Development and Evaluation of the Concise Fidelity for Mindfulness-Based Interventions Tool.

Global Advances in Integrative Medicine and Health 2023 Carol M. Greco, Graham A Dore, Janice M Weinberg et al.

Mindfulness research and clinical programs are widespread, and it is important that mindfulness-based interventions are delivered with fidelity, or as intended, across settings. The MBI:TAC is a comprehensive system for assessing teacher competence, yet it can be complex to implement. A standardized, simple fidelity/engagement tool to address treatment delivery is needed. We describe the...

DOI: 10.1177/27536130231174234 (opens in new tab) Full text (opens in new tab) Fidelity assessment Medical group visits Mindfulness meditation Online intervention +1

Immediate effects of short-term meditation on sensorimotor rhythm-based brain–computer interface performance

Frontiers in Human Neuroscience December 20, 2022 Jeehyun Kim, Xiyuan Jiang, Dylan Forenzo et al. 4 citations

Introduction: Meditation has been shown to enhance a user's ability to control a sensorimotor rhythm (SMR)-based brain-computer interface (BCI). For example, prior work have demonstrated that long-term meditation practices and an 8-week mindfulness-based stress reduction (MBSR) training have positive behavioral and neurophysiological effects on SMR-based BCI. However, the effects of short-term...

DOI: 10.3389/fnhum.2022.1019279 (opens in new tab) Meditation Mindfulness Brain–computer interface Sensorimotor rhythm +5

Mindfulness-Based Stress Reduction increases stimulated IL-6 production among lonely older adults: A randomized controlled trial

Brain, Behavior, and Immunity May 1, 2022 Emily K. Lindsay, J. D. Creswell, Harrison J. Stern et al.

Loneliness is a potent psychosocial stressor that predicts poor health and mortality among older adults, possibly in part by accelerating age-related declines in immunocompetence. Mindfulness interventions have shown promise for reducing loneliness and improving markers of physical health. In a sample of lonely older adults, this two-arm parallel trial tested whether mindfulness training...

What Are Adverse Events in Mindfulness Meditation?

Global Advances in Health and Medicine 2022 Dhanesh D Binda, Carol M. Greco, Natalia E. Morone

Mindfulness meditation has become a successful treatment of both physical and psychosocial ailments over the past decade. Mindfulness-Based Stress Reduction (MBSR) and Mindfulness-Based Cognitive Therapy (MBCT) are now implemented in various clinical and hospital settings for the treatment of stress, depression, substance abuse, and chronic pain. However, given mindfulness meditation’s...

The design and methods of the OPTIMUM study: A multisite pragmatic randomized clinical trial of a telehealth group mindfulness program for persons with chronic low back pain.

Contemporary Clinical Trials October 2021 Carol M. Greco, Susan A Gaylord, Kim Faurot et al.

Mindfulness-based stress reduction (MBSR) is an evidence-based non-pharmacological approach for chronic low back pain (cLBP), yet it is not readily available or reimbursable within primary care clinics. Primary care providers (PCPs) who wish to avoid prescribing opioids and other medications typically have few options for their cLBP patients. We present the protocol of a pragmatic clinical...

DOI: 10.1016/j.cct.2021.106545 (opens in new tab) Full text (opens in new tab) Medical group visits Mindfulness meditation Online intervention Quadruple aim

Mindfulness-Based Stress Reduction Buffers Glucocorticoid Resistance Among Older Adults: A Randomized Controlled Trial

Psychosomatic Medicine March 3, 2021 Emily K. Lindsay, J. David Creswell, Harrison J. Stern et al. 18 citations

OBJECTIVE: Mindfulness interventions have been effective for improving a range of health outcomes; however, pathways underlying these effects remain unclear. Inflammatory processes may play a role, possibly through increased resistance of immune cells to the anti-inflammatory effects of glucocorticoids (i.e., glucocorticoid resistance, or GCR). Here, we conducted an initial examination of...

DOI: 10.1097/psy.0000000000000928 (opens in new tab) Full text (opens in new tab) Mindfulness-based stress reduction Randomized controlled trial Glucocorticoid Resistance ecology +2

Effects of Long-Term Meditation Practices on Sensorimotor Rhythm-Based Brain-Computer Interface Learning

Frontiers in Neuroscience January 21, 2021 Xiyuan Jiang, Emily Lopez, James Stieger et al.

Sensorimotor rhythm (SMR)-based brain–computer interfaces (BCIs) provide an alternative pathway for users to perform motor control using motor imagery. Despite the non-invasiveness, ease of use, and low cost, this kind of BCI has limitations due to long training times and BCI inefficiency—that is, the SMR BCI control paradigm may not work well on a subpopulation of users. Meditation is a mental...

Mindfulness interventions improve momentary and trait measures of attentional control: Evidence from a randomized controlled trial.

Journal of Experimental Psychology General September 24, 2020 Brian Chin, Emily K. Lindsay, Carol M. Greco et al. 49 citations

Mindfulness interventions have been shown to improve several subcomponents of attention; however, the psychological mechanisms driving these improvements are unknown. Mindfulness interventions train individuals to monitor present moment experiences while adopting an attitude of acceptance toward these experiences. We conducted a theoretically driven randomized controlled trial to test the...

DOI: 10.1037/xge0000969 (opens in new tab) Mindfulness Attentional control Psychological intervention Randomized controlled trial +6

Effects of Long-Term Meditation Practices on Sensorimotor Rhythm Based BCI Learning

bioRxiv Preprint Server September 9, 2020 Xiyuan Jiang, Emily Lopez, James Stieger et al. 2 citations preprint

Sensorimotor rhythm (SMR) based brain-computer interfaces (BCIs) provide an alternative pathway for users to perform motor control using motor imagery (MI). Despite the non-invasiveness, ease of use and low cost, this kind of BCI has limitation due to long training times and BCI inefficiency— where a subpopulation cannot generate decodable EEG signals to perform the control task. Meditation is...

Mindfulness training and systemic low-grade inflammation in stressed community adults: Evidence from two randomized controlled trials

PLoS One July 11, 2019 Daniella K. Villalba, Emily K. Lindsay, Anna L. Marsland et al. 59 citations

Mindfulness interventions have garnered significant attention as a complementary health treatment for many physical and psychological conditions. While some research has shown that mindfulness training can decrease psychological and physiological stress responses, it remains unclear whether mindfulness training impacts inflammation-a predictor of poor health outcomes. In addition, little...

DOI: 10.1371/journal.pone.0219120 (opens in new tab) Mindfulness Psychological intervention Randomized controlled trial Intervention counseling +1

Psychological mechanisms driving stress resilience in mindfulness training: A randomized controlled trial.

Health Psychology May 23, 2019 Brian Chin, Emily K. Lindsay, Carol M. Greco et al. 107 citations

OBJECTIVE: Mindfulness interventions have been shown to reduce stress; however, the mechanisms driving stress resilience effects are not known. Mindfulness interventions aim to teach individuals how to: (a) use attention to monitor present moment experiences; with (b) an attitude of acceptance and equanimity. A randomized controlled dismantling trial (RCT) was conducted to test the prediction...

DOI: 10.1037/hea0000763 (opens in new tab) Mindfulness Randomized controlled trial Clinical psychology Psychological resilience +3

How mindfulness training promotes positive emotions: Dismantling acceptance skills training in two randomized controlled trials.

Journal of Personality and Social Psychology December 1, 2018 Emily K. Lindsay, Brian Chin, Carol M. Greco et al. 221 citations

Mindfulness meditation interventions-which train skills in monitoring present-moment experiences with a lens of acceptance-have shown promise for increasing positive emotions. Using a theory-based approach, we hypothesized that learning acceptance skills in mindfulness interventions helps people notice more positive experiences in daily life, and tested whether removing acceptance training from...

DOI: 10.1037/pspa0000134 (opens in new tab) Mindfulness Psychological intervention Affect linguistics Randomized controlled trial +2

Mindfulness for Chronic Low Back Pain: A Qualitative Analysis

Pain Medicine November 1, 2018 José G Luiggi-Hernandez, Jean Woo, Megan Hamm et al.

Abstract: Objective: Mindfulness is a nonpharmacologic mind-body therapy that has been shown to be effective in older adults with chronic low back pain (cLBP). There are few first-person accounts in the literature that describe the older adult experience and perspective while learning mindfulness and meditation to treat pain. The objective of this study was to investigate dominant themes...

How mindfulness training promotes positive emotions: Dismantling acceptance skills training in two randomized controlled trials

August 21, 2018 Emily K. Lindsay, Brian Chin, Carol M. Greco et al. 9 citations

Mindfulness meditation interventions – which train skills in monitoring present-moment experiences with a lens of acceptance – have shown promise for increasing positive emotions. Using a theory-based approach, we hypothesized that learning acceptance skills in mindfulness interventions helps people notice more positive experiences in daily life, and tested whether removing acceptance training...

DOI: 10.31231/osf.io/hk5gp (opens in new tab) Mindfulness Psychological intervention Affect linguistics Randomized controlled trial +2

A Mindful Approach to Diabetes Self-Management Education and Support for Veterans

The Science of Diabetes Self-Management and Care October 27, 2017 Monica M. DiNardo, Shaddy K. Saba, Carol M. Greco et al. 17 citations

Purpose The purpose of this study is to determine feasibility, satisfaction, and preliminary effects of Mindful Stress Reduction in Diabetes Education (Mind-STRIDE), a mindfulness-based intervention for veterans. Methods The study used a single-group pretest-posttest repeated-measures design. The 90-minute Mind-STRIDE training, adapted from Mindfulness Based Stress Reduction (MBSR), was...

Characteristics of Adults Who Used Mindfulness Meditation: United States, 2012.

The Journal of Alternative and Complementary Medicine July 2017 Natalia E. Morone, Charity G Moore, Carol M. Greco

To describe estimates of the number and characteristics of persons who had used mindfulness meditation in the U.S. Data from 108,131 adults from the 2012 National Health Interview Survey were weighted to produce national estimates representative of the U.S. Persons who used mindfulness meditation were identified by their response to the question "During the past 12 months, did you use...

Mindfulness Meditation Training and Executive Control Network Resting State Functional Connectivity: A Randomized Controlled Trial

Psychosomatic Medicine March 22, 2017 Adrienne A. Taren, Peter J. Gianaros, Carol M. Greco et al. 212 citations

OBJECTIVE: Mindfulness meditation training has been previously shown to enhance behavioral measures of executive control (e.g., attention, working memory, cognitive control), but the neural mechanisms underlying these improvements are largely unknown. Here, we test whether mindfulness training interventions foster executive control by strengthening functional connections between dorsolateral...

DOI: 10.1097/psy.0000000000000466 (opens in new tab) Mindfulness Meditation Attentional control Dorsolateral prefrontal cortex +6

Alterations in Resting-State Functional Connectivity Link Mindfulness Meditation With Reduced Interleukin-6: A Randomized Controlled Trial.

Biological Psychiatry July 1, 2016 J David Creswell, Adrienne A. Taren, Emily K. Lindsay et al.

Mindfulness meditation training interventions have been shown to improve markers of health, but the underlying neurobiological mechanisms are not known. Building on initial cross-sectional research showing that mindfulness meditation may increase default mode network (DMN) resting-state functional connectivity (rsFC) with regions important in top-down executive control (dorsolateral prefrontal...

DOI: 10.1016/j.biopsych.2016.01.008 (opens in new tab) Full text (opens in new tab) Functional connectivity Il-6 Mindfulness meditation Stress +2

A Mind-Body Program for Older Adults With Chronic Low Back Pain: A Randomized Clinical Trial.

JAMA Internal Medicine March 1, 2016 Natalia E. Morone, Carol M. Greco, Charity G Moore et al.

Importance: Treatment of chronic low back pain (LBP) in older adults is limited by the adverse effects of analgesics. Effective nonpharmacologic treatment options are needed. Objective: To determine the effectiveness of a mind-body program at increasing function and reducing pain in older adults with chronic LBP. Design, setting, and participants: This single-blind, randomized clinical trial...

Mindfulness meditation training alters stress-related amygdala resting state functional connectivity: a randomized controlled trial

Social Cognitive and Affective Neuroscience June 5, 2015 Adrienne A. Taren, Peter J. Gianaros, Carol M. Greco et al. 232 citations

Recent studies indicate that mindfulness meditation training interventions reduce stress and improve stress-related health outcomes, but the neural pathways for these effects are unknown. The present research evaluates whether mindfulness meditation training alters resting state functional connectivity (rsFC) of the amygdala, a region known to coordinate stress processing and physiological...

DOI: 10.1093/scan/nsv066 (opens in new tab) Full text (opens in new tab) Amygdala Mindfulness meditation Resting State FMRI Functional connectivity +7

The design and methods of the aging successfully with pain study.

Contemporary Clinical Trials November 15, 2011 Natalia E. Morone, Carol M. Greco, Bruce L Rollman et al.

Chronic low back pain (CLBP) is widespread among older adults (≥ 65 years) and is often treated inadequately. With a rapidly growing aging population, CLBP will increase and so will the demand for treatment. We believe that mind-body therapies can help to meet this demand. We present the methodology of a randomized, controlled clinical trial of 300 individuals with CLBP aged 65 years or older....