Efficacy of Online Conscious Connected Breathwork in Reducing Symptoms of Anxiety: A Quantitative Study
Research Square December 13, 2024
Efficacy of Online Conscious Connected Breathwork in Reducing Symptoms of Anxiety: A Quantitative Study
Research Square
ISSN 2693-5015
196 papers in the library · 84 citations · publishing 2020-2026
Papers
The Effect of Mindfulness-Based Cognitive Therapy on Auditory Hallucinations in Patients with Schizophrenia: A Randomized Controlled Trial
Research Square December 3, 2024
The Effect of Mindfulness-Based Cognitive Therapy on Auditory Hallucinations in Patients with Schizophrenia: A Randomized Controlled Trial
Non-ordinary states of consciousness evoked by breathwork correlate with improved heart-rate variability
Research Square November 21, 2024
Abstract High ventilation breathwork is a breathing practice that involves deep, accelerated breathing over a prolonged duration (> 15 minutes). This basic practice underpins a wide range of traditions, from Pranayama to Holotropic and Conscious-Connected breathwork. Anecdotal reports suggest that it can benefit physical and mental health, often by evoking altered states of consciousness....
The Reporting of Setting in Psychedelic Clinical Trials (ReSPCT) Guidelines: An international Delphi consensus study
Research Square November 18, 2024 Chloé Pronovost-Morgan, Kyle T. Greenway, Leor Roseman 2 citations
Abstract Background Psychedelic substances exhibit complex interactions with the ‘set and setting’ of use, i.e., the internal state of the user and the external environment in which a psychedelic experience takes place. Despite the known importance of these contextual variables, psychedelic research has suffered from methodological weaknesses in reporting extra-pharmacological factors and from...
The Effect of Psychedelics on Individuals with a Personality Disorder: Results from two Prospective Cohort Studies
Research Square October 15, 2024 Alexandra R. Gordon, Brennan M. Carrithers, Broc A. Pagni et al. 3 citations
Abstract Background: Personality disorders (PDs) are characterized by impairments in psychological functioning for which pharmacologic treatments have demonstrated limited efficacy. Psychedelics may offer a possible PD treatment, given preliminary evidence for their potential long-term positive effects on psychological functioning. However, little is known about safety or potential therapeutic...
Ketamine and Psilocybin Differentially Impact Sensory LearningDuring the Mismatch Negativity
Research Square September 26, 2024 Shona G. Allohverdi, Milad Soltanzadeh, André Schmidt et al.
Abstract Ketamine and psilocybin show potential as therapies for various mental illnesses, including major depressive disorder. However, further investigation into their neural mechanisms is required to understand their effects on the brain. By combining computational modelling with electroencephalography (EEG), we examine the effects of ketamine and psilocybin on hierarchical sensory...
Psilocybin ameliorates neuropathic pain-like behaviour in mice and facilitates the gabapentin-mediated analgesia
Research Square September 19, 2024 Maria Maiarù, Tatum Askey, Daniel Allen-Ross et al. 2 citations
Abstract Chronic pain states are challenging to control with current drug therapies. Here, we demonstrate that a single dose of psilocybin can produce a sustained anti-nociceptive effect in a mouse model of chronic neuropathic pain. Beyond this, the single dose of psilocybin caused a dramatic increase in the anti-nociceptive potential of gabapentin, a widely used treatment for neuropathic pain,...
Exploring U.K. cancer doctors’ attitudes toward psilocybin-assisted psychotherapy for cancer-related distress
Research Square September 18, 2024 Shane Mageean, Anderson Daniel, Sara Tai
Abstract Background A diagnosis of cancer is often associated with significant psychological distress. Current approaches to cancer-related distress predominantly fall short of meeting the needs of patients. Recent investigations have shown that administering psilocybin in combination with psychotherapy might be effective at reducing distress in cancer patients. Oncologists are often...
Advanced tractography results agree with communication between Global Workspace and Integrated Information consciousness areas
Research Square September 6, 2024
Advanced tractography results agree with communication between Global Workspace and Integrated Information consciousness areas
Single-Dose Psilocybin Therapy for Alcohol Use Disorder: Pharmacokinetics, Feasibility, Safety, and Efficacy in an Open-Label Study
Research Square August 23, 2024 Mathias E. Jensen, Dea Siggaard Stenbæk, Catharina Messell et al. 1 citation
Abstract Background Psilocybin, a serotonin 2A receptor agonist with psychedelic properties, shows promise as a novel treatment for alcohol use disorder (AUD). While current studies involve two dosing sessions, the effects a single dose have not been investigated. Aims To investigate the pharmacokinetics, feasibility, safety, and efficacy of single-dose psilocybin therapy in AUD. Methods This...
Prevalence and Correlates of Psychedelic Use in Poland: A Study on a Representative Sample of Polish Adults
Research Square August 15, 2024 Paweł Holas, Justyna Kamińska
Abstract Objective Recent years have witnessed a resurgence in research exploring the therapeutic potential of classic psychedelics like psilocybin and LSD for treating mental disorders. However, there is a limited knowledge regarding the epidemiology of classic psychedelics consumption and the factors associated with their recreational use in Poland. Methods A representative sample of Polish...
Large language models auto-profile conscious awareness changes under psychedelic drug effects
Research Square August 8, 2024 Danilo Bzdok, Robin Carhart-Harris, Chloe Savignac et al. 3 citations
Abstract Psychedelic experiences open a colorful view into drug-induced changes in conscious awareness. Small-sample studies on psychedelic drug action have gained traction in recent years. Yet, today’s means for measuring changes in subjective experience are mostly limited to legacy questionnaires of pre-assumed relevance, which could be complemented by bottom-up explorations of semantic...
Immediate Effects of Mindful Awareness in Body-oriented Therapy as an Adjunct to Medication for Opioid Use Disorder.
Research Square July 15, 2024 Cynthia U Price, Kenneth C Pike, Anna Treadway et al.
While effective, medication for opioid use disorder (MOUD) treatment outcomes can be limited by co-occurring polysubstance use, mental health and chronic pain conditions. Interoceptive training may facilitate well-being and support medication treatment for MOUD. This study examined the pre-post effects of the mindfulness-based intervention Mindful Awareness in Body-oriented Therapy (MABT) as an...
`Virtual EMO-Mind´ for Primary School Students: Effects on Mindfulness Skills, Attention, Impulsiveness, and Emotional Stability
Research Square July 8, 2024 preprint
`Virtual EMO-Mind´ for Primary School Students: Effects on Mindfulness Skills, Attention, Impulsiveness, and Emotional Stability
Psilocin fosters neuroplasticity in iPSC-derived human cortical neurons
Research Square June 7, 2024 Målin Schmidt, Anne Hoffrichter, Mahnaz Davoudi et al. 5 citations
Abstract Psilocybin is studied as innovative medication in anxiety, substance abuse and treatment-resistant depression. Animal studies show that psychedelics promote neuronal plasticity by strengthening synaptic responses and protein synthesis. However, the exact molecular and cellular changes induced by psilocybin in the human brain are not known. Here, we treated human cortical neurons...
Kindness is lesser preferable than happiness: Investigating interest in different effects of the Loving-kindness and Compassion Meditations
Research Square June 5, 2024
Kindness is lesser preferable than happiness: Investigating interest in different effects of the Loving-kindness and Compassion Meditations
Effects of brief remote high ventilation breathwork with retention on mental health and wellbeing: A randomised placebo-controlled trial
Research Square April 22, 2024
Effects of brief remote high ventilation breathwork with retention on mental health and wellbeing: A randomised placebo-controlled trial
High-order brain interactions in ketamine during rest and task: A double-blinded cross-over design using portable EEG.
Research Square March 21, 2024 Agustin Ibanez, Rubén Herzog, Florentine Barbey et al. 1 citation
In a double-blinded cross-over design, 30 adults (mean age = 25.57, SD = 3.74; all male) were administered racemic ketamine and compared against saline infusion as a control. Both task-driven (auditory oddball paradigm) and resting-state EEG were recorded. HOI were computed using advanced multivariate information theory tools, allowing us to quantify nonlinear statistical dependencies between...
Lightening the Mind: Comparing Audiovisual Stimulation and Meditation for Mood and Cognition Enhancement
Research Square March 14, 2024 Micah Johnson, Ninette Simonian, Nicco Reggente
Abstract In this randomized, controlled, and double-blind experiment with a relatively large sample (n = 262), a novel technique of audiovisual stimulation (AVS) was demonstrated to substantially improve self-reported mood states by reducing several negative affects, including anxiety and depression, and enhancing performance on mood-sensitive cognitive tasks. Most of the AVS effects were...
Improvements in well-being following naturalistic psychedelic use and underlying mechanisms of change in older adults: A prospective cohort study.
Research Square March 8, 2024 Hannes Kettner, Leor Roseman, Adam Gazzaley et al. 5 citations
Affective symptoms such as anxiety, low mood, and loneliness are prevalent and highly debilitating symptoms among older adults (OA). Serotonergic psychedelics are novel experimental interventions for affective disorders, yet little is known regarding their effects in OA. Using a prospective cohort design, we identified 62 OA (age ≥ 60 years) and 62 matched younger adults (YA) who completed...
Development, Content Validation and Pilot Study Feasibility of Heartfulness Meditation and Yoga Protocol for Anxiety
Research Square February 29, 2024
Development, Content Validation and Pilot Study Feasibility of Heartfulness Meditation and Yoga Protocol for Anxiety
Decreased CO2 saturation during circular breathwork supports emergence of altered states of consciousness
Research Square February 22, 2024 Martha N. Havenith, Max Leidenberger, Jelena Brasanac et al. 3 citations
Abstract Altered states of consciousness (ASCs), induced e.g. by psychedelics, show great potential to treat widespread mental health disorders like depression and PTSD. However, access to such treatments is restricted by legal, medical, and financial barriers. Here, we explore the potential of circular breathwork to serve as an accessible, non-pharmacological alternative to engage similar...
Prefrontal Electrophysiological Biomarkers and Mechanism-Based Drug Effects in a Rat Model of Alcohol Addiction
Research Square February 22, 2024 Bettina Habelt, Dzmitry Afanasenkau, Cindy Schwarz et al.
Abstract Current treatments for alcohol use disorder (AUD) show large heterogeneity in response and thus limited effectiveness and high relapse rates. A precision medicine approach with biomarkers responsive to new treatments is warranted to overcome this limitation. Promising biomarkers relate to prefrontal control mechanisms that are severely disturbed in AUD. This results in reduced...
MicroRNAs underlying the antidepressant effect of psilocybin – Establishing an nCounter pipeline for microRNA-quantification in the pig brain
Research Square January 12, 2024 Erik Kaadt, Rolf Søkilde, Hanne D. Hansen et al.
Abstract Novel treatment strategies are needed to overcome some of the current challenges related to treatment resistance and treatment latency within the psychiatric field. Recently, psilocybin has shown promise as a novel treatment of major depressive disorder. A single dose of psilocybin is associated with lasting changes in personality and mood. In parallel, various studies have indicated...
Developing empathy as a process of re-humanization: insights from South American students and their experiences with contemplative practices.
Research Square January 10, 2024
Developing empathy as a process of re-humanization: insights from South American students and their experiences with contemplative practices.