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Research Square

ISSN 2693-5015

301 papers in the library · 141 citations · publishing 2020-2026

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Ketamine role in the treatment of Maternal depression: effects on offspring behaviour

Research Square Taqwa B. Thanoon, Zeina A. Althanoon preprint

Abstract Maternal depression during pregnancy adversely affects offspring neurodevelopment and behaviour. Typical antidepressants like selective serotonin reuptake inhibitors have limitations due to risks of crossing the placenta. Ketamine has emerged as a promising alternative treatment. This research examined ketamine's effects on offspring of maternally stressed mice. Dams were divided into...