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Sergio Pérez Rosal

University of Ottawa

10 papers in the library · 34 citations · publishing 2023-2026

Papers

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Sustained abstinence in severe ketamine use disorder following ibogaine treatment case report

Frontiers in Psychiatry July 20, 2026 Sergio Pérez Rosal, Sonya C. Faber, Markus Backmund

Substance use disorders (SUD) involving ketamine, cocaine, and alcohol present significant clinical challenges, often characterized by high relapse rates and limited pharmacological options. This case report details a 30-year-old male with a five-year history of severe polysubstance dependence, including daily intranasal ketamine use (2–3 g/day), cocaine, and alcohol, comorbid with recurrent...

Quantifying psilocybin exposure in a natural product–based retreat setting: An observational field method for dose measurement

Psychedelics July 18, 2026 Sergio Pérez Rosal, Sonya C. Faber

Background In natural product psilocybin retreats, "dose" is commonly defined by grams of dried mushrooms, despite substantial batch-to-batch variability in psilocybin content. This limits safety predictability and undermines reproducibility and between-study comparability. We report an observational field evaluation of an existing, ICH Q2(R1)-validated rapid colorimetric/photometric assay...

Changes in trauma symptoms of discrimination after MDMA-assisted psychotherapy for posttraumatic stress disorder.

Scientific Reports July 11, 2026 Monnica T. Williams, Sonya C. Faber, Jordan Sloshower et al.

This preliminary study explored the effects of MDMA-assisted therapy on trauma symptoms related to discrimination, as measured by the Trauma Symptoms of Discrimination Scale (TSDS). A total of five diverse participants, who experienced multiple types of discrimination (e.g., gender, racial/ethnic, social class, age, sexual orientation), were assessed before and after treatment. A paired-samples...

Retreat from Racism: A Psychedelic Group Experience for Racial Stress and Trauma

Psychedelics July 1, 2026 Sergio Pérez Rosal, Sonya C. Faber, M. Myriah MacIntyre et al.

Background Racism and discrimination are pervasive social determinants of health, yet mainstream mental health care often fails to address the psychological sequelae of racial trauma, or race-based traumatic stress (RBTS). While psychedelic-assisted therapy (PAT) has re-entered the scientific mainstream, empirical guidance for culturally attuned, integrative care is limited. This study explores...

Standardization of Psilocybin Dosing in a Natural Product–Based Retreat Setting: A Practical Method for Dose Quantification and Adjustment Across Sessions

Research Square November 17, 2025 Sergio Pérez Rosal, Sonya C. Faber

Abstract Natural variation in psilocybin content across mushroom samples presents a significant challenge to consistent dosing in both research and retreat settings. In this observational report, we describe a pragmatic approach for quantifying psilocybin content in naturally sourced material to ensure more standardized dosing across participants. Eleven individuals participated in a 7-day...

Decreased CO2 saturation during circular breathwork supports emergence of altered states of consciousness.

Commun Psychol April 13, 2025 Martha N. Havenith, Max Leidenberger, Jelena Brasanac et al. 14 citations

Abstract Altered states of consciousness (ASCs), induced e.g. during psychedelic-assisted therapy, show potential to treat prevalent mental health disorders like depression and posttraumatic stress disorder. However, access to such treatments is restricted by legal, medical, and financial barriers. Circular breathwork may present a non-pharmacological and hence more accessible alternative to...

Expert recommendations for Germany’s integration of psychedelic-assisted therapy

BMC Medical Education October 24, 2024 Susanne Birnkammer, Olga Chernoloz, Sergio Pérez Rosal et al. 10 citations

As clinical trials for psychedelics move into phase III in the USA, Europe must address its lag in integrating professional education around psychedelic-assisted therapy (PAT) and supporting psychedelic drug research. This paper evaluates the necessary frameworks for implementing PAT in Germany, emphasizing the nation's potential leadership role within the European Union. With Australia having...

Decreased CO2 saturation during circular breathwork supports emergence of altered states of consciousness

Research Square February 22, 2024 Martha N. Havenith, Max Leidenberger, Jelena Brasanac et al. 3 citations

Abstract Altered states of consciousness (ASCs), induced e.g. by psychedelics, show great potential to treat widespread mental health disorders like depression and PTSD. However, access to such treatments is restricted by legal, medical, and financial barriers. Here, we explore the potential of circular breathwork to serve as an accessible, non-pharmacological alternative to engage similar...

Psychedelika in der Psychiatrie – Entwicklungen und die Stellung in Deutschland

Fortschritte der Neurologie · Psychiatrie January 4, 2023 Uwe Herwig, Lea J. Mertens, Sergio Pérez Rosal et al. 6 citations

Zusammenfassung In den letzten Jahren erlebte die klinische Forschung zur therapeutischen Wirksamkeit von Psychedelika eine Art Renaissance. Der aktuelle Stand wissenschaftlicher Erkenntnisse zur Wirksamkeit bei verschiedenen psychiatrischen Indikationen, wie auch die bereits unter bestimmten Voraussetzungen genehmigungsfähige Anwendung einiger psychedelischer Substanzen in der klinischen...